Both 100% pure stevia extract and erythritol are widely used sugar substitutes that are far better than regular sugar for blood-sugar spikes and tooth decay. They differ in chemistry, taste, side-effect profiles, and emerging safety signals - notably, recent research has raised questions about erythritol and blood-clotting/vascular risk, while stevia's safety record is long and largely favorable when highly purified steviol glycosides are used. Which is "better" depends on your health priorities, tolerance, and culinary needs.
What Are Stevia and Erythritol?
100 pure stevia extract and erythritol are both sweet. They use them in cakes, drinks, and other. So what is stevia and what is erythritol?
What Is Stevia?
The journey from leaf to stevia leaf powder is a tale of modern food science. While one can theoretically use crushed stevia leaves, the result is often a potent, slightly bitter sweetness. To create the consistent, high-purity 100 pure stevia extract found in stores, a sophisticated extraction and purification process is employed. This involves harvesting the leaves, drying them, and then using water or food-grade alcohols to extract the steviol glycosides. These extracts are then further purified and refined to isolate the most desirable glycosides, like Reb A, which have a cleaner, less bitter taste profile. This is where specialized producers come into play. For instance, Guanjie Biotech is a bulk Stevia powder supplier that focuses on providing high-purity steviol glycosides for the food and beverage industry, ensuring a consistent and reliable ingredient for raw stevia powder manufacturers.
What Is Erythritol?
This process typically involves using a starch source, such as non-GMO corn or wheat, which is broken down into glucose. This glucose is then fermented by a natural yeast-like fungus, Moniliella pollinis. The microorganism consumes the glucose and produces erythritol, which is then filtered, purified, crystallized, and dried into the white, granular powder we recognize.
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What are the Sweetness and Calories of Stevia And Erythritol?
When comparing stevia and erythritol, their sweetness intensity and caloric values are two of the most important features to understand, especially for people looking to reduce sugar intake.
Sweetness:
Natural stevia powder is intensely sweet (often 200–400× sugar for pure rebaudioside A), so it's used in tiny amounts or blended. Erythritol is milder (~60–80% as sweet as sugar) and more similar to sugar's bulk and mouthfeel.
Calories:
Stevia = essentially zero calories in typical amounts. Erythritol = almost zero (very low caloric contribution because it's not metabolized to energy).
Baking & texture:
Erythritol behaves more like sugar in recipes (bulk, crystalline structure), though it can recrystallize/have cooling effects. 100 pure stevia extract often needs a bulking agent (e.g., fiber, erythritol, dextrose) to replace sugar's volume and texture in recipes.
Aftertaste:
Many people detect a slight bitter or licorice-like aftertaste with stevia (varies by steviol glycoside type and product purity). Erythritol tastes more sugar-like but can produce a cooling sensation on the tongue.
What are the benefits of stevia and erythritol?
Reducing sugar intake is a major health goal for many people, and alternative sweeteners like 100 pure stevia extract and erythritol have gained widespread popularity because of their unique benefits. Although they differ in structure and sweetness intensity, both offer advantages that make them valuable sugar substitutes.

Blood sugar, insulin, and weight control
• Blood sugar & insulin:
Neither stevia bulk powders (purified steviol glycosides) nor erythritol causes meaningful increases in blood glucose or insulin in healthy people when used instead of sugar, making both suitable options for people with diabetes or those watching glycemic control. Some studies even suggest certain100 pure stevia extract might modestly improve glucose handling, but evidence is mixed and not conclusive for routine therapeutic use.
• Weight management:
Replacing sugar with non-nutritive sweeteners can reduce caloric intake, which may help with weight control if not compensated for by increased calories elsewhere. However, the net effect on long-term weight depends on overall diet and behavior. Sweeteners are tools, not magic bullets.
Digestive tolerance and gastrointestinal effects
• Erythritol.
As a polyol, erythritol has much better GI tolerance than many other sugar alcohols (xylitol, sorbitol). Most of it is absorbed and excreted in urine, so it typically causes less gas and bloating. Still, at high doses, many people experience osmotic diarrhea or loose stools; EFSA and other reviews note diarrhea as a possible adverse effect of high erythritol intake. Tolerance thresholds vary. Some studies cite dose limits around 0.66–1.0 g/kg body weight before symptoms appear, though individual sensitivity differs.
• Stevia.
Highly purified 100 pure stevia extract is generally well tolerated at normal food quantities. Some people may experience mild GI upset if a product contains other ingredients (bulking agents, sugar alcohol blends). Whole stevia leaf and crude 100% pure stevia extract are not cleared for food-sweetener GRAS status in the U.S., and our safety profiles differ.


Dental health
Both erythritol and stevia concentrated powder do not feed oral bacteria the way sucrose does, so they are tooth-friendly alternatives that reduce caries risk compared with sugar. In fact, erythritol has some evidence suggesting it may be more protective against dental plaque and cavities than other polyols because of poor bacterial fermentation in the mouth. Stevia also does not promote cavities.
What is the Safety of Stevia And Erythritol?
When considering sugar substitutes, safety is one of the most important factors. Both 100 pure stevia extract and erythritol are widely used around the world, and regulatory agencies have evaluated their safety in depth. Both are considered safe for the general population.
Stevia (steviol glycosides).
Regulatory agencies have evaluated purified steviol glycosides and consider certain purified preparations GRAS or approved for use in foods at specified levels. The FDA has responded "no questions" to several GRAS notices for purified rebaudioside formulations; EFSA and other agencies have also evaluated steviol glycosides. However, less-processed 100 pure stevia extract have not been given the same broad approvals. This is why product labels that say "stevia" might contain very different ingredients - always check for "rebaudioside A" or "steviol glycosides" and purity specs.
Erythritol.
Erythritol (E968) is approved for use as a sweetener in many jurisdictions and is generally recognized as safe (GRAS). EFSA re-evaluated erythritol in 2023 and noted its potential to cause diarrhea at high intakes and issued warnings about adverse effects at high consumption levels; regulatory decisions often emphasize labeling and maximum use levels in specific products. Importantly, in the last few years, new research has explored possible cardiovascular associations (discussed next) that have led to increased scrutiny.
Which should you choose, Stevia or Erythritol?
To crystallize the differences, here is a direct comparison across key parameters:
Parameter |
Stevia |
Erythritol |
Winner For... |
Source |
Leaves of the Stevia rebaudiana plant |
Fermentation of glucose (often from corn) |
Natural Perception: Stevia |
Sweetness |
200-350 times sweeter than sugar |
60-70% as sweet as sugar |
Ease of Baking: Erythritol |
Caloric Content |
0 calories |
~0.2 calories/gram (effectively 0) |
Tie |
Glycemic Index |
0 |
0 |
Tie (for Diabetics/Keto) |
Aftertaste |
Often has a bitter, licorice-like aftertaste |
Clean taste with a cooling sensation |
Pure Taste Profile: Subjective |
Digestive Effects |
Generally well-tolerated; minimal GI issues |
Excellent tolerance; best among sugar alcohols |
Digestive Sensitivity: Erythritol |
Dental Health |
Non-cariogenic |
Anti-cariogenic (reduces plaque) |
Oral Health: Erythritol |
Common Uses |
Tabletop sweeteners, beverages, yogurts (often in blends) |
Sugar-free baked goods, chocolates, gum, blends |
Versatility in Cooking: Erythritol |
Conclusion:
Both stevia (refined steviol glycosides) and erythritol are safer alternatives to sucrose in that they dramatically lower calories and glycemic impact when substituted for sugar. Regulatory agencies consider both generally safe when used appropriately.
Erythritol has excellent dental benefits and provides sugar-like bulk, but it can cause GI symptoms at high doses and has an ongoing safety discussion about possible links to cardiovascular risk based on observational and mechanistic studies - more research is needed. Stevia is calorie-free, and glycoside formulations carry an ADI (0–4 mg/kg bw/day) set by JECFA/EFSA. Purified steviol glycosides are considered safe in normal food uses. Taste and aftertaste are practical considerations.
Replace a portion of added sugar with 100 pure stevia extract or erythritol (or a blend) to lower calories and blood-glucose impact. If you have GI sensitivity, consider using 100 pure stevia extract or limit your erythritol dose if your food needs bulk stevia powder. Welcome to enquire with Guanjie Biotech at info@gybiotech.com.
References
[1] Anton, S. D., et al. (2010). Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite, 55(1), 37–43.
[2] Ashwell, M. (2015). Stevia, nature's zero-calorie sustainable sweetener: A new player in the fight against obesity. Nutrition Today, 50(3), 129–134.
[3] Höfer, P., et al. (2021). Erythritol is more effective than xylitol and sorbitol in managing oral health. International Journal of Dentistry, 2021, 9962375.
[4] Lail, H., et al. (2021). A comprehensive review of the safety of steviol glycosides. Journal of Dietary Supplements, 18(6), 685-704.
[5] Magnuson, B. A., et al. (2017). Review of the nutritional benefits and safety assessment of erythritol. Food and Chemical Toxicology, 106(Pt B), 506–529.
[6] Witkowski, M., et al. (2023). The artificial sweetener erythritol and cardiovascular event risk. Nature Medicine, 29, 710–718.