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Pure Folic Acid Powder
Other name:Folate
Solubility:Insoluble in cold water, slightly soluble in hot water
Appearance:Pale yellow crystalline powder
Deficiency symptom:Neural tube malformation, megaloblastic anemia, cleft lip and palate, etc
Chemical formula:C19H19N7O6
Molar mass:441.40 g•mol−1
Solubility:1.6 mg/L (25 °C) mg/mL (20 °C)
Melting point:250 °C(482 °F)
Certificates: ISO,HALAL, KOSHER and so on.
MOQ:1KG
Annual output: 15 tons
Delivery: 1-3 working days after payment or PO.
Description
Bulk Folic Acid Powder Manufacturer for Supplement and Nutraceutical Companies
Guanjie Biotech is a professional pure Folic Acid Powder Supplier and Bulk Folic Acid Manufacturer in China, providing high-quality Folic Acid Raw Material for nutraceutical, food, and pharmaceutical applications. Our bulk Folic Acid Powder features high purity, stable quality, and reliable bulk supply. Folic Acid, also known as Vitamin B9, is a Yellow, Yellow-brownish or yellowish-orange, odorless, crystalline powder that is odorless and tasteless. It is widely used in dietary supplements, prenatal nutrition products, and functional foods. We offer Wholesale Folic Acid Powder, COA documentation, competitive Folic Acid Powder prices, and OEM/ODM services for global customers seeking a trusted folic acid ingredient supplier.
Why Choose Guanjie Biotech?
Pharmaceutical Grade Quality Control: Every batch undergoes rigorous HPLC testing, heavy metal ICP-MS analysis, and microbial inspection to ensure 100% batch-to-batch consistency.
Global Compliance & Certifications: Fully certified with ISO9001, ISO22000, HALAL, KOSHER, and non-GMO statements. Third-party testing reports (SGS / Eurofins) are available for every shipment.
Flexible Customization: Supports custom mesh sizes (micronized powders), customized premix formulations, and OEM/ODM private labeling.
Stable Supply Chain & Fast Delivery: Direct factory production with ample stock. Standard lead time is 3–5 working days with full traceability and complete MSDS/COA documentation.
COA:
|
Item of Test |
Quality criterion |
Results of Test |
|
Assay |
97.0~ 102.0% |
98.25% |
|
Related substances |
N-(4-aminobenzoyl)-L-glutamic acid:≤0.5% |
0.2% |
| Solubility | Very slightly soluble in water, insoluble in alcohol | |
|
2,5,6-triaminopyrinidin-4(1H)-one: ≤0.5% |
0.3% |
|
|
Pteroic acid≤1.0% |
0.5% |
|
|
Any other impurity:≤0.5% |
0.2% |
|
|
Total of other impurities:≤3.0% |
0.9% |
|
|
Characteristics: |
Yellow, Yellow-brownish or yellowish-orange, odorless, crystalline powder |
Conform |
|
Heavy metals(ppm) |
≤10 ppm (Lead ≤ 2ppm, Arsenic ≤ 1ppm) |
Conform |
|
Pb |
<2ppm |
Conform |
|
As |
<2ppm |
Conform |
|
Total Plate Count |
<250cfu/g |
Complies |
|
Yeast & Mold |
<50cfu/g |
Complies |
|
Coliforms |
MPN<3.0 |
Absent |
|
S. aureus |
Negative |
Absent |
|
Salmonella |
Negative |
Absent |
How Is Folic Acid Powder Produced?

What Are The folic acid sources?
From the original extract and name, pure folic acid powder is found in large amounts in leafy vegetables. Whole grains of spinach, asparagus, turnips, cabbage, lettuce, Brussels sprouts, cauliflower, soybeans, corn, lentils, peas, sunflower seeds, and other leafy vegetables.
Fruits include cantaloupe, honeydew melon, banana, raspberry, grapefruit, strawberry, orange juice, canned pineapple juice, tomato juice, etc. Animal foods such as animal liver, kidney, poultry meat, and eggs, such as pig liver, chicken, beef, mutton, etc., are also rich in folic acid. However, due to the destruction of folic acid by high temperatures during cooking and the low absorption efficiency of the body, it is still difficult to meet the needs of pregnant women's folic acid in their daily diet.
Therefore, pregnant women must take synthetic USP / EP / CP Grade Folic Acid supplements during pregnancy (or even before pregnancy). Studies have shown that men who take folic acid can also increase sperm quality, reducing chromosomal defects and reducing the risk of Down syndrome in newborns.
Folic Acid Powder Applications & Recommended Dosage Guide
Folic Acid Powder (Vitamin B9 Powder) is a high-value nutritional ingredient widely used in dietary supplements, food fortification, functional beverages, pharmaceuticals, animal nutrition, and personal care formulations. As a reliable folic acid powder supplier, manufacturers can use pure folic acid to develop products supporting folate intake, cell metabolism, DNA synthesis, and red blood cell formation.
Bulk Folic Acid Powder is widely applied in fortified foods, including flour, cereals, infant nutrition, and functional drinks. It helps manufacturers create folate-enriched products. It can be used in
• Fortified wheat flour and grains
• Infant formula powder
• Nutritional beverages
• Meal replacement products
Folic acid is also explored as a cosmetic ingredient in skin care and hair care formulations, including anti-aging creams, serums, and scalp products.
Formulation & Processing Considerations
•Solubility Optimization:
Folic acid is sparingly soluble in water but readily dissolves in alkaline solutions. For aqueous formulations, adjusting the pH slightly (pH 6.5–8.0) or utilizing sodium salt forms enhances solubility.
•Heat & Light Stability:
Food Grade Folic Acid Powder is sensitive to light, UV radiation, and strong acids. It is recommended to store bulk powder in light-protected containers and add it late in high-temperature processing steps.
•Uniformity in Blending:
Due to the low inclusion rates in tablets and dry premixes, geometric dilution or pre-blending with microcrystalline cellulose (MCC) or lactose is advised to achieve homogeneous distribution.
What does folic acid do?
Pure Folic Acid Powder is an important B vitamin that plays a key role in human health. It helps with cell growth, DNA synthesis, and red blood cell production. Adequate folic acid intake is especially important for pregnant women, people with anemia, and those at risk of folic acid deficiency.
98% 99% Purity Folic Acid works together with vitamin B12 to support the growth and maturation of red blood cells. Folic acid is necessary for normal blood cell formation. A lack of Natural Folic Acid Powder can affect red blood cell production and may lead to megaloblastic anemia.
Taking Folic Acid Bulk Powder for Dietary Supplements can help prevent and treat folate-deficiency anemia. It supports healthy blood circulation and helps maintain normal oxygen transport throughout the body.
Bulk folic acid powder plays an important role during pregnancy. High Purity Folic Acid Powder is essential for the normal development of the fetal neural tube. Taking enough folic acid before and during early pregnancy can significantly reduce the risk of neural tube defects, such as spina bifida and anencephaly.
During pregnancy, the body needs more nutrients to support the growth of the baby and placenta. Pure Folic Acid Powder helps produce new cells and supports normal immune system function. It also contributes to the healthy development of the placenta and fetal tissues.
Insufficient folic acid intake during pregnancy may increase the risk of complications. These complications may include premature birth, low birth weight, and preeclampsia. Preeclampsia is a serious pregnancy condition that involves high blood pressure and increased protein levels in urine.
For better pregnancy health, women of childbearing age are often advised to take Supplement Grade Folic Acid Powder before conception. Foods rich in folic acid, such as leafy green vegetables, citrus fruits, beans, and fortified cereals, can also help increase daily intake.
Pure Folic Acid Powder may help support healthy blood pressure levels. Studies have found that high blood pressure is associated with elevated homocysteine levels in the blood. Folic acid can help reduce homocysteine levels by supporting normal homocysteine metabolism.
Folic acid is naturally found in plant-based foods and animal products. However, natural folate from food may not always be easily absorbed by the body. Therefore, Food Fortification Grade Folic Acid is commonly used to help meet nutritional needs, especially for pregnant women.
What Is Folic Acid Used For?
Current studies show that Pure Folic Acid Powder plays an important role in human health. Folic acid deficiency may increase the risk of several health problems. These include neural tube defects in newborns, cardiovascular and cerebrovascular diseases, loss of appetite, megaloblastic anemia, vascular dementia in older adults, and depression.
Studies suggest that Pharmaceutical Grade Vitamin B9 may have potential applications in cancer research. A certain concentration of pure folic acid powder may affect folate metabolism and inhibit the growth of ovarian cancer cells. Research also indicates that folic acid may improve the sensitivity of ovarian cancer cells to chemotherapy drugs. This effect could help enhance the treatment response of chemotherapy. However, more clinical studies are needed to confirm these findings.
Overall, Pure Folic Acid Powder is an important nutritional ingredient with broad medical applications. It plays a key role in disease prevention, health maintenance, and future therapeutic research.
FAQs:
1. Where to buy high-quality Folic Acid Powder in bulk?
High-quality bulk Folic Acid Powder can be purchased directly from certified chemical manufacturers and specialized B2B ingredient distributors such as Shaanxi Guanjie Technology Co., Ltd. Look for verified manufacturers offering standardized 98%–102% HPLC purity with complete COA, MSDS, and GMP documentation.
2. What is the best Folic Acid Powder supplier for supplement manufacturers?
The best Folic Acid Powder supplier provides cGMP-compliant manufacturing, high-purity USP or EP grade materials, batch-to-batch consistency, and robust regulatory documentation. Suppliers offering low MOQs, comprehensive third-party lab testing, custom packaging, and steady global logistics serve supplement manufacturers most effectively.
3. How to choose a reliable Folic Acid Powder manufacturer?
To choose a reliable Folic Acid Powder manufacturer, evaluate their facility certifications (cGMP, ISO 22000, Halal, Kosher), quality control processes, and HPLC testing capabilities. Always request batch-specific COAs, stability data, and sample kits to verify purity, heavy metal limits, and physical mesh uniformity.
4. What certifications should a Folic Acid Powder supplier provide?
A reputable Folic Acid Powder supplier should provide ISO 9001, ISO 22000, cGMP, Halal, and Kosher certifications. Furthermore, they must furnish batch-specific Certificates of Analysis (COA), Allergen Statements, Non-GMO declarations, and MSDS documentation to meet international regulatory and safety compliance standards.
5. What is the difference between Folic Acid and Vitamin B9?
Vitamin B9 is the overarching term for a group of water-soluble compounds, including natural food folate and synthetic forms. Folic Acid is the stable, synthetic form of Vitamin B9 used in bulk dietary supplements, fortified foods, and pharmaceuticals due to its superior shelf-life and heat stability.
6. How is Folic Acid Powder used in dietary supplements?
Bulk Folic Acid Powder is used as an active ingredient in prenatal vitamins, multivitamins, and complex B-vitamin formulations. It is pre-blended or geometrically diluted into tablets, capsules, softgels, or gummies to ensure precise micro-dosage distribution for red blood cell synthesis and fetal development.
7. What documents are required when importing Folic Acid Powder?
Importing bulk Folic Acid Powder requires a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Commercial Invoice, Packing List, Certificate of Origin, and Bill of Lading. Depending on regional customs, a Health Certificate, Non-GMO declaration, and cGMP compliance statement may also be required.
8. How to verify the quality of bulk Folic Acid Powder?
Quality verification requires reviewing the Folic Acid manufacturer's COA and performing independent third-party laboratory testing via High-Performance Liquid Chromatography (HPLC) for purity (98%–102%). Testing should also confirm acceptable limits for heavy metals (lead, arsenic), microbial contaminants, loss on drying, and particle size distribution.
9. Which Folic Acid Powder supplier provides OEM and ODM services?
Established B2B ingredient manufacturers like Guanjie Biotech offer comprehensive OEM and ODM services. They provide custom mesh sizes, premix formulation blending, contract manufacturing, private labeling, and specialized packaging solutions tailored to specific commercial supplement, food, or pharmaceutical requirements.
Factory&Team:

Certification

Package & Shipment

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