Glutathione Bulk Powder

Glutathione Bulk Powder Supplier：

Glutathione (Glutathione Bulk Powder) of Guanjie occurs as a white crystalline powder. It is freely soluble in water, and practically insoluble in ethanol (99.5). Melting point is about 185C (with decomposition). We have independent factories and cooperative factories to promise its output. And we have own own professional team to test its quality or if you need that we can send to the third party testing center. Our high quality and competitive GSH powder, welcome to enquiry us.

Why Choose Guanjie?

● Two independent factories and three production line.

● Professional research team and have own labs

● Provide the third party testing.

● Have strong Collaborators:Northwestern University and Chinese Academy of Sciences research center

 

Identification:

Determine the infrared absorption spectrum of Glutathione, previously dried, as directed in the potassium bromide disk method under Infrared Spectrophotometry <2.25>, and compare the spectrum with the

Reference Spectrum: both spectra exhibit similar intensities of absorption at the same wave numbers.

 

Optical rotation:

<2.49> [a]20D : －15.5 – －17.5° (after drying, 2 g, water, 50 mL, 100 mm).

 

CAS NO.: 70-18-8

(2S)-2-Amino-4-[1-(carboxymethyl) carbamoyl-(2R)-2-sulfanylethylcarbamoyl] butanoic acid [70-18-8] Glutathione, when dried, contains not less than98.0% and not more than 101.0% of C10H17N3O6S.

 

COA:

Test Items		Specification	Result
Description		A white crystalline powder	A white crystalline powder
Assay (bas on dry)		98.0%~ 101.0%	99.0%
Identification	IR	Similar with the Reference Spectrum	Complies
	Optical Rotation	- 15.5°~- 17.5°	- 16.7°
Inorganic impurities	Chlorides	Not more than 200ppm	Complies
	Arsenic	Not more than 2ppm	Complies
	Chlorides	Not more than 200ppm	Complies
	Sulphates	Not more than 300ppm	Complies
	Heavy Metals	Not more than 10ppm	Complies
	Iron	Not more than 10ppm	Complies
	Cadmium	Not more than 1ppm	Complies
	Lead	Not more than 3ppm	Complies
	Mercury	Not more than 1ppm	Complies
	Residue on Ignition	Not more than 0. 1%	0.06%
Organic impurities	Total	Not more than 2.0%	1.3%
	GSSG	Not more than 1.5%	0.4%
Clearity and color of solution		Clear and Colorless	Clear and Colorless
Residual solvents		Meet the requirement	Complies
Loss on Drying		Not more than 0.5%	0.2%
Microbiology	Total plate count	≤1000cfu/g	Complies
	Yeast and mold count	≤100cfu/g	Complies
	Total coliforms	≤100cfu/g	Complies
	E. coli	Absent/10g	Complies
	S. aureus	Absent/10g	Complies
	Salmonella	Absent/10g	Complies
Conclusion		Complies with the standard of USP 41

 

Flow Chart:

At present, there are four methods of glutathione bulk powder preparation: solvent extraction, enzymatic method, fermentation method and chemical synthesis method. Guanjie has two extraction methods, one is enzymatic method and the other is fermentation method. The following focuses on extraction from yeast (brewer's/baker's yeast) cultured with high GSH content, with the following process flow:

 

Saccharomyces cerevisiae

↓

First Stage Fermentation

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Second Stage Fermentation

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Fermentation Liguid Separation

↓

L-Glutathione Enriched Yeast

↓

Extraction

↓

L-Glutathione Enriched Yeast Extract

↓

Purification

↓

L-Glutathione Reduced Solution

↓

Filter

↓

L-Glutathione Reduced Solution

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Crystallization Drying

↓

L-Glutathione Reduced

↓

Packing

↓

Glutathione Reduced Product

 

Advantages：

● High purity:

The Glutathione Bulk Powder extracted from yeast is of high purity, which means it is free from other contaminants or impurities.

● Natural source:

Brewer's or baker's yeast is a natural source of GSH, making it a preferable choice for those seeking natural and organic supplements.

● Cost-effective:

The extraction process of GSH from yeast is relatively less expensive than other sources, making it a cost-effective alternative.

● Easy availability:

Yeast is readily available and is a commonly used ingredient in the food industry. Hence, the availability of GSH extracted from yeast is easy.

 

Stability and Reactivity

● Chemical Stability

Stable under normal temperatures and pressures.

● Conditions to Avoid

Incompatible materials, dust generation, excess heat, strong oxidants.

●Incompatibilities with Other Materials

Oxidizing agents.

●Hazardous Decomposition Products

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

●Hazardous Polymerization:

Has not been reported.