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Berberine Extract Powder

Source: Bark of Phellodendron amurense Rupr
Secification:97% Berberine HCL
Appearance: Yellow crytalline powder
Analysis Method:Titration
CAS No.:633-65-8
Particle Size: 100% pass 80% mesh
Annual supply: 20 tons
Standard: Enterprise Standard, CP 2005, CP2015
Two Factories & Three production lines
GMP standard workshop & two independent laboratories
FDA Cert.
Certifications: Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,SC
Overseas warehouse(NJ,USA)
Delivery term: DHL, FEDEX, Air freight,Sea freight
Provide Free Sample
MOQ: 1KG
Not for Private Person Sale

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Description

Berberine Extract Powder Supplier:

Berberine bulk Powder is Guanjie's most powderful product. It is a high-quality natural product extracted from the bark of Phellodendron amurense Rupr. It contains 97% Berberine HCL, which is a valuable compound with numerous health benefits. The powder is a yellow crystalline substance with excellent purity and quality. Our Berberine is of high quality and meets Enterprise Standard, CP2005 and CP2015. It is odorless, extremely bitter and soluble in hot water, methanol, ethanol and other solvents. We can supply up to 20 tons of our products annually and the particle size of our powder is 100% pass 80% mesh. It can meet your requirements. If you have any questions or would like it, please feel free to contact us.

Berberine bulk Powder

Why Choose Guanjie?

● Cutting-Edge Technology: Guanjie is dedicated to creating innovative and natural products with 16 patented technologies.

● International Certifications: Guanjie has successfully passed various international certification systems including ISO9001, ISO22000, IP (non-GMO), QS, Kosher, and Halal.

● Rigorous Quality Control: Guanjie operates a strict quality control system, performing in-house testing on almost every aspect of products, including assays, water content, odor, heavy metals, solvent residue, pesticide residue, protein, microbiological properties, and more.

● Professional Shipping: With over 20 years of experience, Guanjie has established strong partnerships with professional shipping agents, ensuring safe and prompt delivery of their products.

Product Introduction:

Berberine extract powder is a yellow-colored compound that is extracted from certain plants, such as the Berberis shrub, turmeric, and goldenseal. Berberine is thought to exert its medicinal effects by affecting various enzymes and pathways in the body. It is available in dietary supplement form, typically as a powder or capsule.

Specification

SANALYSIS ITEM

SPECIFICATION

METHOD

Assay:

Berberine Hydrochloride

≥97 0%

HPLC(on anhydrous basis)

Appearance

Color

Odor & taste

Identification

Loss on Drying

Total ash

Sieve analysis

Fine Powder

Yellow

characteristic

Identical to R.S. sample

≤12.0%

≤0.5%

100% through 80 mesh

Organoleptic

HPTLC

Eur.Ph.7.0<2.8. 17>

Eur.Ph.7.0<2.4. 16>

USP36<786>

Heavy metals:

Lead(Pb)

Arsenic(As)

Cadmium(Cd)

Mercury(Hg)

≤3.0 mg/kg

≤2.0 mg/kg

≤1.0 mg/kg

≤0 1 mg/kg

Eur.Ph.7.0<2.2.58>ICP-MS Eur.Ph.7.0<2.2.58>ICP-MS Eur.Ph.7.0<2.2.58>ICP-MS Eur Ph 7 0<2 2 58>ICP-MS

Residual solvents

Residual pesticides

Non irradiated

Meet Eur.Ph.7.0 <5.4>

Meet USP36<561>

≤700

Eur.Ph.7.0<2.4.24>

USP36<561>

EN13751:2002<PSL>

Microbiology

Total Plate Count

Yeast & Mold

E.Coli

Salmonella

Non irradiated ≤10000cfu/g ≤1000cfu/g Negative Negative

USP36<61>

USP36<62>

Crystallization Conditions

● Add hydrochloric acid to the filtrate after the crude berberine extraction to adjust the pH to 2.0, keep it at rest for 3-4 days, and it will naturally crystallize.

● Pump it to the plate and frame filter for filtration, drain the liquid away, and leave the solid for drying, which is crystal berberine.

● The powder berberine we usually see is obtained by crushing the crystal berberine.

Crystallization Conditions

● Add hydrochloric acid to the filtrate after the crude berberine extraction to adjust the pH to 2.0, keep it at rest for 3-4 days, and it will naturally crystallize.

● Pump it to the plate and frame filter for filtration, drain the liquid away, and leave the solid for drying, which is crystal berberine.

● The powder berberine we usually see is obtained by crushing the crystal berberine.

Production Process

● Selection of the raw plant material:

The plant material for the extraction of Berberine Extract Powder is usually selected based on its potency, quality and availability. Most commonly, the plant material used for Berberine extraction is the root and stem of Berberis aristata or Berberis vulgaris.

● Cleaning and preparation:

The selected plant material is thoroughly cleaned to remove any debris, dirt, or foreign matter. The cleaned plant material is then cut into small pieces and dried in a controlled environment to prevent the loss of active ingredients and to ensure uniform drying.

● Grinding and powdering:

The dried plant material is then ground into a fine powder using a grinder or mill. The powdered material is then passed through a sieve to remove any coarse particles or impurities.

● Extraction:

The powder is then subjected to extraction using a solvent such as ethanol, methanol or water. The extraction is usually carried out using a series of extraction tanks or columns.

● Filtration:

After the extraction, the Berberine Extract Powder is filtered to remove any impurities or solid particles. The filtration is usually carried out using a filter press or a filtration unit.

● Concentration:

The filtered extract is then concentrated using a rotary evaporator or vacuum concentrator to increase the concentration of the active ingredients.

● Drying:

The concentrated extract is then dried using a spray dryer or freeze dryer to obtain Berberine bulk Extract.

● Packaging:

The final product is then packed in airtight containers and stored at a cool, dry and dark place.

Dosage

The recommended dosage of berberine extract powder varies depending on the intended use and individual factors such as age, weight, and health status. Generally, a typical dosage for berberine extract powder is 500-1500mg per day, divided into 2-3 doses. It is also recommended to take berberine with meals to improve absorption and minimize any potential side effects.

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