Curcumin Extract Powder

Brief Introduction

Curcumin extract powder is a diketone compound extracted from the rhizome of some plants in the ginger family and Tennantaceae. Turmeric contains 0.3-5.4% curcumin, an orange yellow volatile oil composed mainly of turmerone,atlantone and zingiberone. Curcumin provides 95% Curcuminoids. Curcumin is orange-yellow crystalline powder, slightly bitter, insoluble in water and ether, soluble in ethanol, propylene glycol, easily soluble in glacial acetic acid and alkaline solution, reddish-brown in alkaline, yellow in neutral and acidic. Curcumin has strong stability to reducing agents, strong coloring, once colored, it is not easy to fade, but sensitive to light, heat, iron ions, light resistance, heat resistance, iron ion resistance is poor.

With a sound enterprise quality assurance system, Guan jie implements the strict quality control standards. It is tested by HPLC, three peaks in finger print.pure natural extract,USP standardWe are a professional team to produce,research and sale on Curcumin extract bulk powder. We have different sizes of products. Common total curcumin 10%-95% (CP version, USP version), water soluble total curcumin 10%-30%, turmeric oleoresin, turmeric oil, etc. It has the characteristic odor of turmeric, and the powder is yellow or reddish. We can provide you with high quality products at the best price, as a professional natural herb products supplier, Guan jie is your best choice.

COA

MOA:

Curcumin content(HPLC) determination method

Summary of methodology

After the sample was dissolved by ultrasound, it was determined by HPLC and quantified by external standard method.

II. Instruments and tools

   Analytical Balance,(Sensitivity 0.00001g).

   Ultrasonic cleaning instrument: 250W, 20kHz.

   High performance liquid chromatography (with ultraviolet detector)

III. Reagents and solutions

① Acetonitrile. Chromatographic purity;    

②Methanol; chromatographic purity;   

③ glacial acetic acid; chromatographic purity;

④ HPLC grade water or MILIQ water;

4. Reference substance of curcumin: purity of HPLC ± 98%.

Five Chromatographic Conditions and System Applicability

5.1 CHROMATOGRAPHIC CONDITIONS

A) Chromatographic column: octadecylsilane bonded silica gel column, 4.6 mm X 250 mm.

B) mobile phase: acetonitrile-4% glacial acetic acid solution (48:52), filtered by an organic system 0.45 um filter membrane, and prepared by ultrasonic.

C) Flow rate: 1.00 ml/min.

D) detection wavelength: 430 nm.

E) Column temperature: 30 ℃

5.2 System serviceability

The theoretical plate number should not be less than 4000 according to the calculation of curcumin peak.

VI. Methods of operation

6.1 Sampling

   The samples were sampled according to the method in Appendix II A of the 2010 edition of the Pharmacopoeia of the People's Republic of China.

6.2 Preparation of Control Solution

   The reference substance of curcumin (about 10 mg) was weighed accurately, placed in a 100 mL brown bottle, ultrasonic dissolved with methanol and diluted to a scale to obtain a reference substance solution of 0.10 mg/ml.

6.3 Preparation of solutions for test products

   Take an appropriate amount of turmeric extract powder (according to the content), accurately weigh, put into a 100mL brown bottle, add about 80mL methanol, extract for 15 minutes by ultrasonic, take out, put into room temperature, dilute with methanol to the scale, shake well.The test solution was obtained by filtering the filtrate with organic 0.45 um microporous filter membrane and placing the filtrate in a brown sample bottle.

6.4 Methods of measurement

   The reference solution and the sample solution were precisely absorbed and injected into the liquid chromatograph respectively, and the content was determined by external standard method.

Note: The chemical property of curcumin is not stable. The control and the sample solution should be detected within 2 hours after preparation.

7 Result Calculation

The content is calculated according to formula (C1):

   (C1)

    In the formula:

AX-The total peak area of the three components in the chromatogram of the sample solution;

The peak area of curcumin in the solution chromatogram of AS reference substance;

C — — The concentration of curcumin in the solution of the reference substance is mg/mL;

V — — The volume of the solution of the sample, and the unit is milliliter (mL);

M — — The volume of test sample, and unit is mg.

Applications

● Food additives

Turmeric extract has long been widely used in the food industry as a commonly used natural pigment, mainly in the coloring of canned food, intestinal products and sauce and marinade products, and the amount used depends on the normal production needs. The product form of functional food with curcumin as the main ingredient can be general food or some non-food forms, such as capsules, pills or tablets. For the general food form, some yellow vegetarian food products can be considered, such as pastries, sweets, beverages, etc.

Curcumin is a food additive approved by the Codex Alimentarius Commission of the Food and Agriculture Organization of the United Nations (FAO/WHO-1995), and is one of the first nine natural pigments allowed to be used in food as promulgated in China's Hygienic Standard for the Use of Food Additives.

● Chemical Indicator

Used as an acid-base indicator, pH 7.8 (yellow)-9.2 (red-brown).

● Medicine

Turmeric is commonly used as medicine, and its main bioactive components are curcumin-like and volatile oil. The former has hypolipidemic, anticoagulant, antioxidant and choleretic effects, while the latter mainly acts as an anti-inflammatory, antibacterial and cough suppressant. 

Function:

● Alzheimer's disease

Animal experiments at Duke University showed that curcumin in curry not only broke down amyloid in the brains of lab rats, but also prevented the production of this protein. The researchers noted that regular curry consumption may also produce similar effects in humans, thus helping to prevent Alzheimer's.

● Anti-inflammatory

Inflammation is a complex process that is triggered by cellular infection and/or tissue damage, producing a series of chain reactions that ultimately lead to the rapid progression of certain chronic diseases. Studies have found that the anti-inflammatory activity of curcumin extract powder is comparable to that of steroids and NSAIDs.

Factory&Team：

Certification

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