Gymnema Extract Powder

Gymnema Extract Powder Supplier:

Guanjie Biotech has focused on Gymnema Extract Powder research, production, and exporting for 20 years. Gymnemic Acid is its active ingredients with 25% and 50% specifications. We have strong R&D capability to produce high-quality products. This product applies Gravimetry test method to test the assay. As a professional supplier, welcome to contact Guanjie Biotech.

Why Choose Guanjie?

● Gymnema Extract Powder Free sample available for quality approval.

●20 years experience

● Have strong Collaborators: Northwestern University andthe  Chinese Academy of Sciences research center

●Provide customized packing service

●Professional and efficient after-sales service.

 

COA

Item	Specification	Result	Method
Basic Product Information
Genus and Species	Gymnema sylvestre	Conform	/
Part of the Plant	Root	Conform	/
Country of Origin	China	Conform	/
Marker Compounds
Gymnemic acids	>25%	26.45%	Gravimetric
Organoleptic Data
Appearance	Fine powder	Conform	GJ-QCS-1008
Color	Voilet red	Conform	GB/T 5492-2008
Odor &Taste	Characteristic	Conform	GB/T 5492-2008
Process Data
Solvent(s) Used	Grain alcohol/water	Conform	/
Drying Method	Spray drying	Conform	/
Excipient	None	Conform	/
Physical Characteristics
Loss on Drying	<5.0%	3.54%	GB/T 14769-1993
Ash Content	<4.0%	2.18%	AOAC 942.05, 18th
Solvent Residue	Eur. Pharm	Conform	GJ-QCS-1007
Heavy Metals
Total Heavy Metals	<10ppm	Conform	USP <231>, method II
As	<2.0ppm	Conform	AOAC 986.15, 18th
Pb	<2.0ppm	Conform	AOAC 986.15, 18th
Cd	<0.5ppm	Conform	AOAC 986.15, 18th
Hg	<0.5ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	<1,000cfu/g	62cfu/g	AOAC 990.12, 18th
Yeast & Mold	< 100cfu/g	Conforms	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

Chemical Properties

Gymnema Extract Powder is derived from the leaves of Gymnema sylvestre. The extract contains a rich profile of bioactive compounds, among which gymnemic acids, saponins, flavonoids, and alkaloids are the most prominent. These chemical constituents contribute to its distinctive therapeutic effects and physicochemical properties.

Gymnemic Acids

The primary bioactive constituents in Gymnema Extract Powder are gymnemic acids, a group of triterpenoid saponins. These compounds are structurally glycosides composed of an oleanane-type aglycone (sapogenin) and sugar moieties such as glucuronic acid or galactose. Gymnemic acids are responsible for the characteristic "anti-sweet" activity of the plant, temporarily suppressing the perception of sweetness by interacting with taste receptor cells.

Chemically, Gymnemic Acid powder products are amphipathic molecules, exhibiting both hydrophilic and lipophilic properties, which influence their solubility and interactions in biological systems. They are typically insoluble in water but soluble in alcohol and organic solvents such as methanol and ethanol, making alcohol-based extraction the preferred method for powder production.

Saponins

Saponins are another important group of compounds found in Gymnema Extract Powder. These natural glycosides are known for their surface-active properties. Chemically, they consist of a hydrophobic aglycone (triterpenoid or steroidal in nature) and one or more hydrophilic sugar chains. In aqueous solutions, saponins can form foams when agitated-this property is often used in qualitative identification.

The presence of saponins contributes to Gymnema's beneficial effects on lipid metabolism, glucose uptake, and cholesterol regulation. They also act as natural emulsifiers, which can influence the formulation of nutraceuticals and functional foods.

Flavonoids And Polyphenols

Flavonoids present in Gymnema Extract Powder include quercetin, kaempferol, and their derivatives. These polyphenolic compounds are known for their antioxidant activity. Chemically, they contain two aromatic rings connected by a three-carbon bridge and often have hydroxyl groups that confer strong radical-scavenging abilities.

Their antioxidant properties contribute to Gymnema's protective effects against oxidative stress and inflammation, particularly in pancreatic and liver tissues.

Alkaloids And Other Phytochemicals

Alkaloids in Gymnema Extract Powder are nitrogen-containing compounds that contribute to its pharmacological profile, although in lower concentrations than saponins or gymnemic acids. They may play supportive roles in blood sugar regulation and neuromodulation.

Other compounds include resins, tannins, and volatile oils, each contributing minor but synergistic effects.

Physicochemical Characteristics

●Appearance:

The Gymnema Extract Powder product typically presents as a fine, free-flowing powder with a characteristic brownish or greenish hue, depending on its source and processing method. Its uniform texture and ease of handling make it suitable for various food, nutraceutical, and cosmetic applications.

●Solubility:

The powder dissolves readily in alcohol, allowing for easy incorporation into alcohol-based formulations such as tinctures and liquid extracts. However, it has limited solubility in water, which may affect its dispersibility in purely aqueous solutions and should be considered during formulation development.

●Taste:

The Gymnema Extract Powder taste profile is distinctly bitter with a pronounced astringency, which may influence the overall sensory characteristics of end products. For applications where taste is a critical factor, flavor-masking strategies or encapsulation techniques may be employed to improve palatability.

●pH Range:

When dissolved in aqueous media, the Gymnema Extract Powder generally exhibits a slightly acidic to neutral pH range, depending on concentration and formulation conditions. This pH behavior makes it compatible with a wide variety of product matrices without significantly altering the overall acidity or alkalinity.

 

 

Qualitative Analysis of Total:

The total saponins present in Gymnema Extract Powder can be qualitatively analyzed using a variety of established techniques. These methods help identify the characteristic properties and confirm the presence of saponins in the extract. Commonly employed chemical tests include the positive Lippmann reaction and Salkowski reaction, which indicate saponin presence through color changes in the reaction medium. A simple shake test using a neutral 1% aqueous solution can also provide an initial indication-persistent foam or small bubbles forming upon agitation suggests the presence of saponins due to their surfactant properties.

Further confirmation can be obtained through acid hydrolysis, which breaks down saponins into their sugar and sapogenin components, allowing for detailed structural identification. Spectroscopic techniques such as ultraviolet (UV) absorption and infrared (IR) absorption spectroscopy are used to detect specific functional groups and absorbance patterns unique to saponins.

Additionally, thin-layer chromatography (TLC) serves as an effective tool for the separation and identification of saponin compounds based on their migration behavior on a silica plate. These combined methods provide a comprehensive qualitative analysis of the total saponins in Gymnema Extract Powder, ensuring its phytochemical authenticity and consistency.

 

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Certification

 

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