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Spermidine Supplier
Spermidine trihydrochloride 98%
Product standard:98%、1.0%
Character:Fine white powder
Two Factories & Three production lines
GMP standard workshop & two independent laboratories
FDA Cert.
Certifications: Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,SC
Overseas warehouse(NJ,USA)
Delivery term: DHL, FEDEX, Air freight,Sea freight
Provide Free Sample
MOQ: 1KG
Not for Private Person Sale
Description
Spermidine Powder Wholesale Supplier | Customized Packaging and OEM Service Available:
As a leading global Spermidine supplier and wholesale Spermidine manufacturer, Guanjie Biotech provides both high-purity synthetic Spermidine Trihydrochloride 98% and natural Wheat Germ Extract Spermidine. We meet strict global dietary supplement and pharmaceutical raw material standards with complete batch traceability and third-party laboratory verification.
|
Specification / Parameter |
Spermidine Trihydrochloride 98% (Synthetic) |
Wheat Germ Extract Spermidine (Natural)
|
|
CAS Number |
334-50-9 |
124-20-9 |
|
Chemical / Molecular Formula |
C7H19N3 · 3HCl |
C7H19N3 (Natural Complex) |
|
Source / Origin |
Chemical Synthesis (Synthetic Butylenediamine route) |
Natural Wheat Germ (Non-GMO Raw Material) |
|
Assay / Active Purity |
≥ 98.0% (HPLC / GC) |
1.0% / 0.5% (HPLC / GC) |
● Spermidine trihydrochloride 98% is an off-white powder. Its CAS No. is 334-50-9. The raw material is butylenediamine. The process is synthetic. Spermidine Trihydrochloride is general cargo. We have transportation identification. Spermidine trihydrochloride, or low levels of spermidine, is effective in slowing down the aging process. Of course, it's also used as a health ingredient for improving cognition, improving cardiovascular health, anti-cancer, and so on.

● And the amount of spermidine 98% is not so big. It is difficult to produce. It is a colorless, transparent liquid. Its CAS No. is 124-20-9. It is unstable, liquid at high temperature and solid at low temperature. The transportation identification of spermidine is a class 8 dangerous good.
Why Choose Guanjie Biotech?
● Professional research team and have our own labs.
● Provide third-party testing.
● Have strong Collaborators: Northwestern University and the Chinese Academy of Sciences research center.
● Provide customized packing service.
● Professional and efficient after-sales service.
What Is Spermidine?
Spermidine trihydrochloride powder is a polyamine compound that naturally occurs in living cells and is involved in various biological processes such as cell growth, differentiation, and apoptosis. It is found in various foods such as wheat germ, soybeans, corn, and mushrooms. Guanjie Biotach is a professional spermidine supplier. It has been shown to have anti-aging, anti-inflammatory, and antioxidant effects in some studies.
COA:
|
Test Items |
Specification |
Result |
MOA |
|
Appearance |
White to off-white power |
Off-White Powder |
Visual |
|
Purity |
≥98% |
99.0% |
GC |
|
Solubility |
Soluble in water |
Conform |
CP2020 |
|
Loss on drying |
≤1.0% |
0.28% |
CP2020 |
|
Residue on ignition |
0.2% |
0.02% |
CP2020 |
|
Ethanol(GC) |
5000ppm |
600ppm |
GC |
|
Heavy Metal Content |
|||
|
Pb |
≤0.1 ppm |
Conform |
GB5009 |
|
Hg |
≤0.1ppm |
Conform |
GB5009 |
|
Cd |
≤0.2 ppm |
Conform |
GB5009 |
|
As |
≤0.1ppm |
Conform |
GB5009 |
|
Total microbial count |
≤500CFU/g |
<10 |
GB4789 |
|
Coliform |
≤0.92MPN/g |
Conform |
GB4789 |
|
Mold and yeast |
≤50CFU/g |
Conform |
GB4789 |
|
Staphylococcus aureus |
0/25g |
Conform |
GB4789 |
|
Salmonella |
0/25g |
Conform |
GB4789 |
|
Conclusion |
All inspection items are in conformity with the specifications. |
||
|
Storage Condition |
Sealed packaging, stored at cool, dry and away from light. |
||
Spermidine Flow Chart:

How is spermidine produced?
1. Guanjie Biotech is a spermidine supplier. The process of extracting wheat germ spermidine and the stability of wheat germ.
Separating the endosperm, germ, and bran of wheat germ and then breaking its structure is the process of flour processing. After separation, the density, size, and shape of wheat germ and bran have very significant differences, and wheat germ can be separated by a special grading sieve and suction fan.
Since wheat germ contains a variety of substances that are easily oxidized, it is susceptible to spoilage. Therefore, before using wheat germ as food and feed, it should be treated by physical or chemical methods so that the stability of the germ can be guaranteed.
2. Technologies for processing wheat germ.
(1) Physical method. The physical methods are the wet heat method and the dry heat method.
● The moist heat method refers to the use of steam at a relatively high temperature to destroy the oxidizable substances in wheat germ, thus making it easier to store.
● The dry heat method refers to the use of infrared radiation and other equipment to dry wheat germ and other operations to preserve its flavor and extend its shelf life.
(2) Chemical method.
The chemical method refers to the use of chemicals to inhibit the activity of enzymes and kill bacteria, thus prolonging the preservation of wheat germ.
Atlas:

Differences Between Synthetic Spermidine and Natural Wheat Germ Extract Spermidine
Guanjie Biotech is a Spermidine supplier. Our products are divided into Synthetic Spermidine and Natural Wheat Germ Extract Spermidine. For commercial applications, bulk spermidine ingredients are mainly supplied through chemical synthesis or natural extraction from wheat germ extract. Although both sources provide spermidine, they differ in origin, composition, production process, regulatory positioning, and market applications.
| Comparison | Synthetic Spermidine | Natural Wheat Germ Extract Spermidine |
|---|---|---|
| Source | Produced through chemical synthesis using controlled chemical reactions | Extracted and purified from wheat germ, a natural food source |
| Origin | Synthetic / non-natural production route | Plant-derived natural ingredient |
| Main Active Compound | Spermidine trihydrochloride or pure spermidine | Naturally occurring spermidine with wheat germ matrix components |
| Purity Level | Usually available at very high purity (commonly ≥98% or ≥99%) | Typically standardized to a specific spermidine content (for example 0.5%, 1%, 2%, 5%) |
| Production Process | Multi-step chemical synthesis, purification, crystallization, drying | Wheat germ extraction, filtration, concentration, purification, and drying |
| Composition | Mainly contains isolated spermidine compound | Contains spermidine plus naturally occurring wheat germ nutrients such as peptides, phospholipids, vitamins, minerals, and polyphenols |
| Consistency | Highly consistent batch-to-batch due to controlled synthesis | May vary depending on wheat variety, cultivation conditions, and extraction technology |
| Clean Label Positioning | Less suitable for "natural", "plant-based", or "food-derived" marketing | Better aligned with natural, clean-label, and plant-based trends |
| Cost | Usually lower production cost at large scale | Higher due to raw material processing and extraction complexity |
| Application | Pharmaceutical research, high-dose formulations, research-grade products | Nutraceuticals, dietary supplements, functional foods, anti-aging formulations |
| Consumer Acceptance | Some markets prefer pure synthetic compounds | Often preferred by consumers seeking natural ingredients |
FAQs:
A: We have discovered that wheat germ contains a high concentration of natural spermidine, which is why it is one of our primary sources. We ensure that our supplements are rich in spermidine and meet our high-quality standards by testing the wheat germ before and after our proprietary extraction process.
Q2: What certifications have you passed?
A: We are a spermidine supplier that has a GMP standard workshop & two independent laboratories. And we passes Halal,ISO9001, PAHS Free ,NON-GMO ,KOSHER,SC and other patents.
Q3: Is it safe to consume spermidine?
A: Absolutely! You are likely already consuming spermidine in your daily diet. In addition, current research suggests that a diet rich in spermidine may even have potential health benefits, such as extending lifespan.
Q4:What is the recommended daily amount ?
A: Our research has led us to recommend a higher intake of spermidine throughout one's life to maintain optimal cellular performance and longevity. We suggest a daily dose of 1 mg of spermidine, which has been confirmed by our third-party laboratory.
Q5: What is the main difference between Synthetic Spermidine 98% and Natural Wheat Germ Spermidine?
A: Spermidine Trihydrochloride 98% (CAS 334-50-9) is a highly purified synthetic salt ideal for high-potency, low-dosage capsule formulations where consistent purity and clinical dosage control are required. Natural Wheat Germ Extract Spermidine (0.5%–1.0%) is an all-natural plant extract preferred by clean-label brands seeking plant-derived, non-synthetic labeling.
Q6: What is the Minimum Order Quantity (MOQ) and packaging standard?
A: Our standard MOQ is 1 KG for sample testing and pilot production. Standard wholesale packaging includes 1 kg/aluminum foil bag, 5 kg/carton, and 25 kg/fiber drum with internal sealed PE liners.
Q7: Can you assist with OEM / Custom Formulation and Liposomal processing?
A: Yes, we offer OEM/ODM services, including liposomal powder processing, custom mesh sizing, premixes, and private label ingredient blending in our GMP-compliant processing lines.
What is spermidine used for?
Spermidine powder is a naturally occurring polyamine compound that has attracted increasing attention in the nutraceutical, cosmetic, and pharmaceutical industries. As a functional ingredient, high-purity spermidine powder is widely used in dietary supplements, anti-aging formulations, and research-based health products due to its potential role in cellular health and longevity-related applications.
Commercially available spermidine trihydrochloride powder, especially spermidine trihydrochloride 98%, is commonly used as a standardized raw material for supplement manufacturers. With growing consumer interest in healthy aging and preventive nutrition, bulk spermidine powder has become an important ingredient for global nutraceutical brands.
Spermidine Powder in Dietary Supplements
In the dietary supplement industry, spermidine powder is mainly used as a longevity and healthy aging ingredient. Spermidine is widely studied for its relationship with autophagy, a natural cellular process responsible for removing damaged or unnecessary cellular components and supporting cellular renewal.
Due to its potential connection with cellular maintenance, spermidine supplements are marketed for supporting healthy aging, cardiovascular health, cognitive function, and overall wellness. Supplement manufacturers often use spermidine trihydrochloride 98% powder as a stable and standardized ingredient for capsules, tablets, and functional nutrition products.
As demand increases for anti-aging supplement ingredients, spermidine has gained attention among companies developing premium nutraceutical formulations focused on longevity, cellular health, and preventive wellness.
Spermidine Powder in Cosmetics
Spermidine is also used as an innovative cosmetic ingredient in skincare formulations targeting skin aging and renewal. Cosmetic manufacturers incorporate spermidine into anti-aging products due to its potential role in supporting cellular activity and maintaining skin health.
In skincare applications, spermidine cosmetic ingredients are developed for products such as facial serums, creams, and specialized anti-aging formulations. It is commonly positioned as a functional ingredient that may support skin renewal, improve skin appearance, and complement other active compounds used in advanced skincare products.
With the growing market demand for science-based beauty products, spermidine is becoming a valuable ingredient for brands developing premium anti-aging skincare solutions.
Spermidine Powder in Pharmaceutical Research
In pharmaceutical and biotechnology research, spermidine has been investigated for its potential biological activities, including antioxidant and anti-inflammatory properties. Studies have explored its relationship with cellular protection mechanisms, oxidative stress regulation, and age-related health conditions.
Although further clinical research is required to confirm specific therapeutic applications, spermidine remains an important research compound in areas related to neurodegenerative disorders, metabolic health, and aging biology.
Pharmaceutical companies and research institutions may use high-purity spermidine powder as a specialized raw material for experimental studies and product development.
Choosing a Reliable Spermidine Powder Supplier
For companies sourcing bulk spermidine powder, selecting a professional spermidine powder manufacturer is essential to ensure product quality, purity, and supply consistency. A reliable supplier should provide standardized specifications, strict quality control, and suitable documentation for international markets.
High-quality spermidine trihydrochloride powder should meet requirements for purity, stability, and application compatibility. As demand continues to grow for longevity supplement ingredients and cellular health products, spermidine powder is expected to remain an important functional ingredient in the global nutraceutical market.
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Certification

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