Microcrystalline Cellulose Powder

Introduction

Microcrystalline Cellulose Powder (MCC, Microcrystalline cellulose), the main component is a linear polysaccharide bound by β-1,4-glucosidic bonds, is a natural cellulose hydrolyzed to the limit degree of polymerization (LODP) by dilute acid. Free-flowing, extremely fine short rod-like or powder-like porous particles, composed of white, odorless, tasteless crystalline powder.The source of microcrystalline cellulose is made from plant cellulose by hydrolysis and post-processing . It is roughly a process: dilute inorganic acid solution hydrolysis of α-cellulose, where α-cellulose can be made from the fiber pulp of cellulose-containing plants. The hydrolyzed cellulose is filtered, purified and spray dried to form porous particles with wide particle size distribution.

Guanjie is a good quality microcrystalline powder bulk supplement. And we have professional researching, producing,testing and sale team. The quality of our products can be promised. It is widely used in pharmaceuticals, cosmetics, food and other industries. Different particle sizes and water content have different characteristics and application ranges.

Specification:

Application

● Pharmaceutical industry

It is commonly used as adsorbent, suspending agent, diluent, disintegrant. It is widely used in pharmaceutical preparations, mainly used as diluent and binder in oral tablets and capsules, not only for wet granulation but also for dry direct compression.

It can also be used as a sustained release agent for pharmaceuticals. The sustained release process is the entry of the active substance into the porous structure of the carrier. The active material is contained by intermolecular hydrogen bonds, and the active material is fixed after drying.

It can form a stable dispersion system in water, and it can be mixed with medicine to make creamy or suspended medicine liquid, and can also be used as capsule.

● Food industry

In the food industry, Microcrystalline Cellulose, as an edible fiber and an ideal health food additive, can maintain the stability of emulsification and foam, maintain the stability of high temperature, and improve the stability of liquid. It has been approved by the United Nations Food and Agriculture Organization and the World Health Organization With the certification and approval of the Joint Appraisal Committee of Food Additives to which the organization belongs, corresponding fiber commodities also appear and are widely used in dairy products, frozen foods, meat products, etc.

● Cosmetics

It can be used as an ingredient in the manufacture of a variety of cosmetics, skin treatment and care products, and cleaning detergents.

Compound applications：

● Lactose and microcrystalline cellulose complexes (9:1, 3:1) are designed for fast disintegration of hard tablets obtained by direct compression.

The advantages are: reduction of mixing process, reduction of dust generation, avoidance of waste in wet granulation, improvement of material flow and content uniformity during tablet pressing.

● MCC and glycerol monostearate compound is a direct-pressing excipient designed for high-speed tablet pressing, which can effectively ensure the uniformity of tablets.

● Microcrystalline cellulose complexed with sodium carboxymethyl cellulose can be used as suspension stabilizer in suspension and dry suspension formulations.

Precautions

Other studies have found that how long magnesium stearate dissolves has no effect on the effectiveness of the drug. It also does not change the dissolution of the tablet or the potency of the supplement or drug. There is also concern that magnesium stearate can lead to the formation of harmful biofilms in the digestive system. Biofilms occur when bacterial groups form a protective barrier.

These claims come from the fact that soap contains magnesium stearate and forms a scum film. But your gut wall is different from your bathroom wall or door and won't have the same scum membrane.

allergen. Allergic reactions to magnesium stearate are rare, but if it affects you, you should avoid it and consult your doctor.

Safety

Microcrystalline Cellulose Powder is widely used in oral pharmaceutical preparations and food, and is relatively non-toxic and non-irritating. It is not absorbed after oral administration, has almost no potential toxicity, may cause mild diarrhea when used in large quantities, and has no difficulty as a pharmaceutical excipient. Abuse of certain preparations containing fibrin, such as inhalation or injectable administration, can lead to fibrin granuloma.

MCC has been listed in GRAS (generally recognized as safe: generally recognized as safe (US FDA term)). It is approved as a food additive in Europe. Included in FDA's Inactive Component Guidance (for inhalation; oral capsules; granules; suspensions; syrups; tablets; topical and vaginal administration). It is approved for use in non-injectable formulations in the UK. Canada includes it in the list of acceptable non-pharmaceutical ingredients.

Compatibility.

It has contraindications for compatibility with strong oxidizing agents.

Pharmacopeial standards and their inclusion, or relevant official standards：

● Chinese Pharmacopoeia 2015, Part IV P601-P605

● USP, EP, IP, JP, BP are included

● Pharmaceutical Excipients Handbook, 4th and 6th editions

Why choose us?

● Our products are certified with ISO 9001-22000, SC, KOSHER, HALAL,

● Strict quality control and the best after-sales service

● There are professional salesman and provide you satisfying service.

If you want our bulk Microcrystalline Cellulose,please feel free to send email at nancy@gybiotech.com or call us at +862988253271

Our factory:

There are two factories both in Baoji city and Shangluo City, Guanjie factories covers an area of 7000㎡, including GMP standard workshop of 2000㎡.

Product Qualification

Microcrystalline Cellulose Powder is produced in a clean working environment and every step of the process is conducted by highly qualified professionals.

Testing Center:

Both the production processes of manufacture and the product itself meet all international standards. And if you need our testing report, we can provide you.

Certification

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

Package&Warehouse:

Payment term

We accept L/C, D/A, D/P, T/T, Western Union, MoneyGram, Paypal.

Delivery term

● Dhl

● Fedex

● Sea freight

● Air transport

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