Bulk Egg Yolk Lecithin

Egg Yolk Lecithin Supplier:

Guanjie Biotech's bulk egg yolk lecithin is a milky white or light yellow powder or wax-like agglomerate, with a slight, special smell and creamy touch. We have 30% egg yolk lecithin powder and 80%-98% egg yolk lecithin wax with high quality and competitive price. Welcome to enquiry: info@gybiotech.com.

COA:

Testing Item	Standards	Inspecting Result
【Description】
Appearance	Milky white or light yellow wax-like agglomerate, with a slight special smell and creamy touch	Light yellow wax-like agglomerate
Character	Soluble in Ethanol, Ether, and, Chloroform and petroleum ether(boiling range of 40~60oC), almost insoluble in acetone and water.	Conform
【Identification】	complies	complies
【Check】
Acid Value	n.m.t.20.0	14.3
Saponification Value	195-212	198
Iodine Value	60-73	69
Peroxide Value	n.m.t.3.0	1.4
Free Fatty Acid	n.m.t.1%	Conform
Triglyceride	n.m.t.3%	Conform
Cholesterol	n.m.t.2%	Conform
Palmitic Acid	n.m.t.0.2%	Conform
【Related Substance】
Phosphatidylinositol	n.m.t.5.0%	0.35%
Lysophosphatidyl Ethanolamine	n.m.t.1%	0.8%
Sphingomyelin	n.m.t.3.0%	1.6%
Lysophosphatidylcholine	n.m.t.3.5%	2.0%
Lysophosphatidy Ethanolamine	n.m.t.4.0%	2.8%
Total Amount of Related Substances	n.m.t.8.0%	4.8%
【Residual Solvents】
Ethanol	n.m.t.0.2%	0.007%
Acetone	n.m.t.0.2%	NOT DETECTED
Ether	n.m.t.0.2%	NOT DETECTED
Petroleum Ether	n.m.t.0.05%	0.0005%
Hexane	n.m.t.0.02%	NOT DETECTED
Total Residual Solvent	n.m.t.0.5%	0.007%
Water	n.m.t.3%	1.2%
Protein	Not detected	NOT DETECTED
Heavy Metals	n.m.t.5ppm	Conform
Arsenic	n.m.t.0.0002%	Conform
Endotoxins	n.m.t.2.0EU	Conform
Bacteriological account
Aerobes	n.m.t.100cfu/g	<10CFU/G
Molds and Yeasts	n.m.t.100cfu/g	<10CFU/G
E.Coli	Negative/g	NOT DETECTED
Salmonellae	Negative/g	NOT DETECTED
Assay
Nitrogen(N)	1.75~1.95%	1.8%
Phosphorus(P)	3.5%~4.1%	3.6%
Phosphatidylcholine	n.l.t.68%	80.5%
Phosphatidylethanolamine	n.m.t.20%	10.3%
Phosphatidylcholine and Phosphatidylethanolamine	n.l.t.80%	90.8%
Conclusion： Complies with China Pharmacopoeia 2015 requirement for Injection

What Is Egg Yolk Lecithin?

Bulk Egg Yolk lecithin is a natural mixture of phospholipids obtained by extracting and refining egg yolks. It is an amphiphilic molecule. One end is a hydrophilic nitrogen- or phosphorus-containing head, and the other end is a hydrophobic lipophilic) long hydrocarbon-based chain. Depending on the type of backbone alcohol, egg yolk lecithin is divided into two main groups. One group has glycerol as its backbone and is called glycerophospholipids, while the other group has sphingomyelin as its backbone and is called sphingolipids.

 

What Does Egg Yolk Lecithin Do?

Pure egg yolk lecithin has many essential physiological functions, such as antioxidant activity, antimicrobial activity, anti-inflammatory activity, improvement of fat metabolism, retinal protection, improvement of cardiovascular management, and brain health. The following briefly introduces the functional activities of egg yolk lecithin supplement, such as antioxidant, antibacterial, anti-inflammatory, neuroprotection and cardiovascular protection.

 

● Antioxidant activity

The antioxidant activity of bulk egg yolk lecithin was reported as early as 1992. It is particularly good in retarding the oxidative degradation of edible salmon oil. Studies have shown that the degree of unsaturation of fatty acids in egg yolk lecithin is positively correlated with its antioxidant capacity. This indicates that the more unsaturated fatty acid chains there are, the greater the antioxidant activity. In the molecular structure of egg yolk lecithin, hydroxylamine groups on the side chains of phosphatidylcholine and phosphatidylethanolamine have a significant ability to inhibit lipid peroxidation. The hydroxylamine groups prevent the oxidative chain reaction of lipids by trapping oxygen radicals, thus reducing the rate of lipid oxidation and prolonging the shelf life of food. It was also found that the addition of nitrogen to egg yolk lecithin granules further enhanced its antioxidant properties. This may be related to the ability of elemental nitrogen to trap free radicals.

In the food industry, the use of antioxidants is an important means of extending the shelf life of fats, oils and other lipid-rich foods. Compared to chemically synthesized antioxidants, bulk egg yolk lecithin is not only safer as a natural antioxidant but also provides nutritional support. Therefore, egg yolk lecithin has a wide range of applications in the processing and storage of fatty foods.

● Antimicrobial activity

The antimicrobial activity of pure egg yolk lecithin is mainly reflected in its ability to form nanoscale liposomes or micelles. It can encapsulate antimicrobial active substances and bind to microbial cells through liposomes. This releases the antimicrobial active substance and achieves the effect of inhibiting or killing the microorganism. This mechanism is similar to a targeted delivery system for drugs. It releases the active ingredient in a specific environment and enhances the antimicrobial effect.

This property of bulk egg yolk lecithin is of great importance in the field of food and medicine. Liposomes can form stable micellar structures in the aqueous phase, effectively encapsulating and protecting the antimicrobial substances from rapid decomposition in the ex vivo environment. In addition, due to the biocompatibility of egg-based lecithin, it has low irritation to human tissues and cells in antimicrobial applications. Antimicrobial liposomes made from egg yolk lecithin can be applied not only for food preservation and shelf-life extension, but also for antimicrobial coating of medical devices and delivery of therapeutic drugs.

 

● Anti-inflammatory activity

The anti-inflammatory activity of egg yolk lecithin is related to its role in regulating the inflammatory factors NF-κB and MAPK pathways during cellular metabolism. Studies have shown that lecithin can reduce the inflammatory response of the body by inhibiting the upregulation of these inflammatory factors. Inflammation is the body's defense mechanism to cope with injury and infection. However, excessive inflammatory responses can lead to tissue damage and disease. Therefore, proper regulation of the inflammatory response is important for maintaining good health.

The presence of unsaturated fatty acid chains in egg yolk lecithin is believed to be a key factor in its anti-inflammatory activity. Unsaturated fatty acids can bind to cell membranes. It stabilizes the cell membrane structure and reduces cell membrane lipid peroxidation, which in turn reduces the production of inflammatory factors. Especially in the management of chronic inflammatory diseases, egg yolk lecithin shows good potential. Not only can bulk egg yolk lecithin be used as a dietary supplement to modulate inflammatory responses in the body, but it can also be used as a carrier for anti-inflammatory ingredients in drug discovery and development to improve the bioavailability of drugs.

 

● Neuroprotective Functions

Neurodegenerative diseases can lead to memory loss and cognitive decline. Studies have found that intake of egg yolk lecithin significantly improves memory and cognitive function and slows the onset of neurodegenerative diseases. This effect is closely related to the unsaturated fatty acid chains in bulk egg yolk lecithin. Unsaturated fatty acids are important components of neuronal cell membranes. They enhance the fluidity and stability of the cell membrane. This helps maintain the normal function of nerve cells.

In addition, egg yolk lecithin can increase the level of acetylcholine in the brain by inhibiting the activity of acetylcholinesterase, thus improving the efficiency of neurotransmission. Acetylcholine is an important neurotransmitter in the brain and is involved in memory and learning processes. By regulating the metabolism of acetylcholine, egg yolk contains lecithin has a significant effect in slowing down cognitive decline and improving memory. At the same time, egg yolk lecithin can also reduce oxidative stress in the brain, reducing nerve cell damage and further exerting neuroprotective effects.

 

● Cardiovascular protective function

Cardiovascular disease is one of the leading causes of death worldwide. Hypertension is an important contributor to cardiovascular disease. Bulk egg yolk lecithin has been shown to help regulate blood pressure by inhibiting the activity of angiotensin-converting enzyme (ACE), thereby reducing the risk of hypertension. Angiotensin-converting enzyme is an important enzyme that regulates vasoconstriction.It raises blood pressure by producing angiotensin II. Egg yolk lecithin inhibits the activity of this enzyme. This reduces the production of angiotensin II, which leads to a lowering of blood pressure.

 

In addition, phosphatidylcholine in egg yolk lecithin can lower the level of low-density lipoprotein cholesterol (LDL-C) in the blood. This helps to improve the lipid profile. High levels of LDL-C are one of the main causes of atherosclerosis. It deposits on the walls of the arteries and forms plaques, leading to the narrowing and hardening of the blood vessels. By lowering LDL-C levels, egg yolk lecithin can reduce the risk of atherosclerosis and protect cardiovascular health.

 

In the prevention and management of cardiovascular disease, bulk egg yolk lecithin can be used not only as a dietary supplement alone but also in combination with other cardiovascular protective ingredients such as fish oil and coenzyme Q10. This will achieve a better synergistic effect.

 

What Is Egg Yolk Lecithin Used For?

In the 1960s, fatty milks were developed and marketed by Fresenius Kabi based on egg yolk lecithin. Since then, natural phospholipids have become essential excipients in the development of fatty emulsions. It is used in a large number of medicines, such as propofol emulsion injection, propofol medium/long-chain fat emulsion injection, flurbiprofen injection, prostaglandin injection, medium/long-chain fat emulsion injection, etc. It is also used in the production of fat emulsions.

In addition, bulk egg yolk lecithin can be used to make liposomes and also as an emulsifier in fat injection. It is also effective in the clinical prevention of cardiovascular and cerebrovascular diseases and the treatment of tumors. In the food industry, egg yolk lecithin has also been widely used in various kinds of health food and baby food. This is used to meet the body's demand for lecithin at different times.

 

● Propofol Emulsion Injection

Propofol, as a short-acting intravenous anesthetic, is one of the commonly used sedative drugs for the induction of anesthesia. Bulk egg yolk lecithin is an oil-in-water (O/W) emulsion with egg yolk lecithin as the emulsifier.

Other Ingredients: Soya bean oil (for injection), egg yolk lecithin, glycerol (for injection), disodium edetate, sodium hydroxide and water for injection.

 

● Alprostadil Injection

Prostadil is mainly used for myocardial infarction, thrombophlebitis, occlusive arteriosclerosis and other conditions.

Other ingredients: Soybean Oil, Egg Yolk Lecithin, Oleic Acid, Glycerol, Sodium Hydroxide

 

● Flurbiprofen Ester Injection

Flurbiprofen ester is used for analgesia after surgery and for various types of cancer. The advantage is that it has no central inhibitory effect. It does not affect the awakening of patients under anaesthesia and can be used immediately after surgery.

Other Ingredients: Soya bean oil, bulk egg yolk lecithin, concentrated glycerol, sodium hydrogen phosphate hydrate, pH regulator

 

● Medium/Long Chain Fatty Milk Injection (C6-24)

Medium/Long Chain Fatty Lactose Injection (C6~24) Liquid is used in patients who need to receive parenteral gastrointestinal nutrition and/or have essential fatty acid deficiency.

Other ingredients: refined egg yolk lecithin, glycerol and water for injection, an appropriate amount of sodium hydroxide

 

Company Advantages:

Guanjie Biotech's factory is fully qualified. We have many kinds of SC extract production licenses, carry out the record production of traditional Chinese medicine extracts, and are the record manufacturer of export food production. We have various quality, HALAL and KOSHER certificates. The facilities and equipment are standardized, and the production quality management system is complete.

We have a competent testing capacity complete, technology, production, and quality team. We can provide customized products with various active ingredients for customers' bulk egg yolk lecithin specific business and usage needs. At the same time, to meet the high-end customer factory inspection, extended audit, and filing needs.

 

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