NAD Bulk Powder

Bulk NAD powder Supplier:

NAD bulk powder has attracted increasing attention for its potential benefits in anti-aging, energy metabolism, and health maintenance. Guanjie Biotech is a supplier of NAD powder. We provide NAD bulk powder with an assay >98%. It is a white powder. It is high quality and competitively price. Welcome to enquiry at info@gybiotech.com.

COA

Test Items	Specification	Result
Appearance	White to yellowish powder	Conform
Purity(HPLC)	≥98%	99.3%
Assay of β-NAD(enzym.) (calc. on dry basis)	≥97%	98.4%
Sodium Content(IC)	≤1%	0.082%
Water Content(KF)	≤5%	2.74%
pH Value in water(100mg/ml)	2.0-4.0	2.31
Methanol(By GC)	≤1%	0.015%
Ethanol(By GC)	≤2%	0.0054%
Heavy metal content(AAS)
Pb	≤0.5ppm	Conform
As	≤0.5ppm	Conform
Hg	≤0.5ppm	Conform
Cd	≤0.5ppm	Conform
Total microbial count(GB 4789.2)	≤750 CFU/g	10CFU/g
Coliform(GB 4789.3)	<3MPN/g	N.D
Conclusion: Conform to the standard
Storage conditions: Room temperature in a dry place, long-term storage at -25ºC to -15ºC

 

 

Test Report:

What is NAD?

Nicotinamide Adenine Dinucleotide is referred to as NAD. NAD is a coenzyme widely present in organisms and plays a key role in energy metabolism, cell repair, and aging regulation. Its content is closely related to cell health. With age, the level of NAD in the human body gradually decreases, thus affecting a variety of physiological functions.

 

Structure and classifications

NAD is a dinucleotide composed of nicotinamide, adenine, two ribose molecules (Ribose) and phosphate groups (Phosphate). NAD can be divided into the following two main forms in the body:

• Oxidized NAD

It mainly participates in the redox reaction in the metabolic process and is a key factor in cellular energy metabolism. As a coenzyme, NAD bulk powder interacts with dehydrogenases to help catalyze a variety of metabolic reactions in organisms. Such as glycolysis, tricarboxylic acid cycle and oxidative phosphorylation.

•Reduced NAD

It is converted by NAD+ after accepting electrons in biochemical reactions. Its main function is to act as an electron carrier to provide energy to the electron transport chain during cellular respiration. NADH releases energy during oxidation and promotes the synthesis of ATP. This can support cell function and life activities.

In addition, NAD can be further converted into NADP (nicotinamide adenine dinucleotide phosphate), which is mainly involved in biosynthesis, especially in the synthesis of fatty acids and nucleotides.

 

Biological effects

NAD has many important biological functions in the human body. It is not only the core component of cellular energy metabolism, but also involves many aspects such as cell repair, immune regulation and anti-aging.

•Participation in energy metabolism

NAD powder participates in important energy metabolism processes such as glycolysis, tricarboxylic acid cycle (TCA cycle) and oxidative phosphorylation in cells. Through these processes, nicotinamide adenine dinucleotide powder can help cells convert chemical energy in food into ATP. It can provide cells with various physiological activities.

•DNA repair and gene expression

NAD+ is a necessary condition for the activation of NAD-dependent deacetylases (Sirtuins). Sirtuins play an important role in DNA repair and gene expression regulation. The level of NAD+ directly affects the activity of Sirtuins. This affects the cell's repair ability, gene expression and aging process.

•Anti-aging effect

With age, the level of NAD bulk powder in the body gradually decreases. This is considered to be an important cause of aging and age-related diseases. The lack of NAD+ may lead to cell function decline, metabolic disorders and decreased immunity. By supplementing NAD+, it is expected to delay the aging process and improve various health problems related to aging.

•Immunomodulatory effect

NAD+ has an important influence on the regulation of the immune system. NAD+ can enhance the body's immune response and help fight infections and other diseases by regulating the function of immune cells.

 

Aging and metabolism of NAD+

•NAD+ and aging

With age, the level of NAD+ in the body decreases significantly. This is closely related to a variety of aging-related diseases (such as diabetes, cardiovascular disease, neurodegenerative diseases, etc.). The decline in NAD+ levels not only affects energy metabolism but also reduces the efficiency of DNA repair and accelerates the aging process. Studies have shown that supplementing NAD+ can delay the aging process and improve the metabolism and immune function of the elderly population.

•NAD+ and metabolic diseases

Low NAD+ levels are closely related to the occurrence of metabolic diseases. For example, diseases such as diabetes, obesity, and non-alcoholic fatty liver disease are all related to NAD+ deficiency. By supplementing NAD+ or activating the synthesis pathway of NAD+, the symptoms of these diseases can be improved, and it is even possible to cure or reverse some metabolic diseases.

 

Application in the field of anti-aging

NAD+ has become an important direction in current anti-aging research because of its potential impact on aging and aging-related diseases. By increasing the level of NAD+, not only can the aging process be improved, but also the occurrence of aging-related diseases can be effectively slowed down.

•Delaying aging

Pure nad+ powder helps repair damaged DNA and protect cells from oxidative damage by activating deacetylases such as Sirtuins. It can delay the aging process. In addition, NAD+ can also promote the health of mitochondria and enhance the energy production capacity of cells, further helping anti-aging.

•Improving cognitive function

The importance of NAD+ in the brain is gradually being discovered. Studies have shown that NAD+ deficiency may be associated with a decline in cognitive function, memory loss, and the occurrence of neurodegenerative diseases. By increasing NAD+ levels, it is expected to improve cognitive function and delay or prevent the occurrence of neurodegenerative diseases.

•Improving muscle health

NAD bulk powder is essential for the health of muscle cells. As we age, a decrease in NAD+ levels may lead to a loss of muscle mass and strength. By supplementing NAD+ precursors, muscle function can be improved and exercise endurance and recovery can be enhanced.

•Promoting cardiovascular health

NAD+ levels are closely related to cardiovascular health. Studies have shown that NAD+ deficiency is closely related to the occurrence of cardiovascular diseases such as hypertension, arteriosclerosis and heart disease. By supplementing NAD+, cardiovascular health can be improved and the risk of disease can be reduced.

 

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