L-ergothioneine powder and glutathione bulk powder are two important bioactive substances that have attracted much attention. Each plays a unique and critical role in the body. They are irreplaceable in maintaining normal cell function and coping with various internal and external pressures. Guanjie Biotech is a high-purity glutathione and ergothioneine supplier, provides high-quality products to the market.
Introduction
1. Ergothioneine
• Definition and Discovery:
Ergothioneine is a naturally occurring sulfur-containing amino acid first isolated from ergot in 1909. However, it is not widely synthesized in organisms; it can only be synthesized by itself in some specific microorganisms and a few plants.
• Structural Features:
Ergothioneine has many special chemical properties, including a certain acid-base buffering capacity. Its chemical structure contains an imidazole ring and a sulfur atom, which provides it with antioxidant active sites.
• Physiological Function:
Ergothioneine is a powerful intracellular antioxidant that can specifically protect cells from damage caused by oxidative stress. It can play an antioxidant role in many ways. For example, it can directly remove free radicals from cells and regulate the redox signaling pathways. In addition, ergothioneine is also involved in the detoxification process of cells, helping cells excrete harmful substances and maintain the stability of the intracellular environment.
• Distribution:
In the human body, L-ergothioneine powder is mainly enriched in some tissues and organs more sensitive to oxidative stress. Such as the liver, kidneys, heart, eyes, and brain. This shows that these tissues and organs have a high demand for ergothioneine's antioxidant and protective functions.
2. Glutathione
• Definition and discovery:
Glutathione (glutathione, GSH) is a tripeptide compound composed of glutamic acid, cysteine, and glycine. It was first discovered in 1888.
• Structural characteristics:
In glutathione's structure, the thiol group (-SH) on the cysteine residue is the key group for its biological function. This thiol group has a strong reducing property and can easily give out electrons, which makes it an antioxidant.
• Physiological function:
Glutathione bulk powder plays multiple roles in organisms. First, it is an important antioxidant that can remove various free radicals produced in cells. Such as superoxide anions, hydrogen peroxide, etc. Secondly, bulk supplements pure glutathione-reduced powder participate in cells' detoxification process. It can combine with some toxic substances. It can be converted into non-toxic or low-toxic substances and then excreted from the body. In addition, glutathione also plays an important role in maintaining redox balance in cells, regulating immune function, and participating in DNA synthesis and repair.
• Distribution:
Glutathione is widely distributed in various tissues and cells of the human body. Whether in metabolically active organs such as the liver and kidneys, or in tissues such as skin and muscles, glutathione can be detected. Its concentration in cells is relatively high, and it is one of the important substances for maintaining redox homeostasis in cells.
Differences in chemical properties
Glutathione and ergothioneine have different chemical properties.
1. Composition and structure
• Ergothioneine:
Ergothioneine is a sulfur-containing amino acid. Its structural core is an imidazole ring connected to a sulfur-containing side chain. This structure is relatively stable. Ergothioneine can undergo redox reactions under certain conditions. But its reactivity is lower than that of the sulfhydryl group in glutathione.
• Glutathione:
As a tripeptide compound, the uniqueness of glutathione lies in the free sulfhydryl group on the cysteine residue. This sulfhydryl group has strong nucleophilicity and reducibility. Glutathione bulk powder can quickly react with oxidants in aqueous solution, giving electrons and being oxidized to oxidized glutathione (GSSG). This structural feature determines the high efficiency and sensitivity of glutathione in redox reactions.
2. Solubility and stability
• Ergothioneine:
Ergothioneine has a certain solubility in water. But relatively speaking, its solubility is not as good as glutathione. This is because the hydrophobic imidazole ring part in its molecular structure affects its dispersibility in water. In terms of stability, bulk L-ergothioneine powder is relatively stable at room temperature and neutral pH. However, in high temperatures, strong acid or alkaline environments, its structure may change, resulting in reduced activity.
• Glutathione
Glutathione has good water solubility. The presence of multiple polar groups in its molecules. Such as carboxyl, amino, etc. However, due to the high reactivity of its thiol group, glutathione is easily oxidized in the air. The oxidation rate will be accelerated, especially in the presence of catalysts such as metal ions. Therefore, glutathione needs to be stored at low temperatures and sealed conditions to maintain its reduction activity.
Applications:
1. Health care products
• Ergothioneine:
In the healthcare products market, ergothioneine has attracted attention for its antioxidant and cell protection functions. It is often added to high-end antioxidant health care products, claiming to delay aging, improve the body's antioxidant capacity, protect important organs, etc. It is especially suitable for middle-aged and elderly people and people who have been in high-pressure and highly polluted environments for a long time.
• Glutathione:
Glutathione is one of the common ingredients in the healthcare products market. In addition to antioxidant and immune-enhancing products, glutathione is widely used in beauty and skincare products due to its whitening effect. Glutathione is added to many whitening oral liquids, capsules,and other products, claiming to inhibit melanin production and achieve the effect of whitening skin.
2. Cosmetics
• Ergothioneine:
Ergothioneine is mainly used as an antioxidant and skin protectant in cosmetics. It can protect skin cells from oxidative damage caused by ultraviolet rays, environmental pollution and other factors, reduce the formation of wrinkles, and delay skin aging. At the same time, L-ergothioneine powder is suitable for people of all skin types due to its mildness to the skin.
•Glutathione:
The application of glutathione bulk powder in cosmetics mainly focuses on whitening and anti-oxidation. It can achieve the effect of whitening by inhibiting the activity of tyrosinase and reducing the synthesis of melanin. In addition, the antioxidant effect of glutathione can help the skin resist the damage of free radicals and maintain its elasticity and luster.
Why Choose Guanjie Biotech's L-ergothioneine And Glutathione?
As a high-purity glutathione and ergothioneine supplier, Guanjie Biotech has significant advantages in product quality and characteristics.
•L-ergothioneine powder:
The purity of our company's L-ergothioneine bulk powder is ≥98%. The effectiveness and stability of our products when used in the fields of medicine, health care and cosmetics. It is in the form of white fine particles, which ensures that the product is easy to handle and formulate. Whether L-ergothioneine powder is in the preparation of pharmaceutical preparations, health care products or cosmetics formulations, it can be easily mixed with other ingredients. We strictly control every link from raw material selection to the production process to ensure the quality and consistency of the product.
•Glutathione powder:
Guanjie Biotech's glutathione bulk powder is a white crystal or crystalline powder with a purity of ≥99.0%. Our product is more effective in anti-oxidation and whitening. It is easily soluble in water and transparent. It can be quickly dissolved and evenly dispersed in the formulation of cosmetics and health products, improving the stability and use effect of the product.
We have independent laboratories and factories, and through a strict quality control system, we ensure that each batch of products meets high-quality standards. At the same time, we supply the market at a competitive price, providing customers with a very cost-effective choice. Customers from all walks of life are welcome to inquire and explore the application potential of ergothioneine and glutathione in different fields.
Although both glutathione and ergothioneine play an important role in anti-oxidation and cell protection. However, there are many differences in their chemical properties, biosynthesis and metabolism, physiological functions and application fields. The high-purity L-ergothioneine powder and glutathione bulk powder provided by Guanjie Biotech provide a high-quality raw material basis for in-depth research and application of these two substances in related fields. Welcome to enquiry us: info@gybiotech.com.
