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Andrographis Paniculata Extract Powder
Appearance: Light brown to white powder
Part Used: the whole herb or Leaf
Secification:1%~98%
Active Ingedients: Andrographolide
Testing Method:HPLC
Identification:TLC
CAS No.:5508-58-7
Annual Supply Capacity:More than 50 Tons
Two Factories & Three production lines
GMP standard workshop & two independent laboratories
FDA Cert.
Certifications: Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,SC
Overseas warehouse(NJ,USA)
Delivery term: DHL, FEDEX, Air freight,Sea freight
Provide Free Sample
MOQ: 1KG
Not for Private Person Sale
Description
Andrographis Paniculata Extract Powder Supplier:
Guanjie Biotech specializes in Andrographis paniculata extract powder. Andrographis paniculata bulk extract powder is a light brown to white powder appearance and is made from the whole herb or leaf of Andrographis Paniculata. Our powder is available in 1%~98% specifications. And it contains Andrographolide, which is an active ingredient that has been widely studied for its potential health benefits. Our product is tested using HPLC to ensure consistency and quality. As an Andrographolide supplier, we have an annual supply capacity of more than 50 tons, and we are committed to providing our customers with high-quality Andrographis Paniculata Extract Powder at competitive prices.

COA:
|
ANALYSIS ITEM |
SPECIFICATION |
METHOD |
|
Assay: |
||
|
Andrographolide |
≥98.0% |
HPLC |
|
Appearance |
Fine Powder |
Organoleptic |
|
Color |
White |
Organoleptic |
|
Odor & taste |
Bitter |
Organoleptic |
|
Identification |
TLC |
TLC |
|
Loss on drying |
≤5.0% |
IR |
|
Residue on ignition |
≤5.0% |
2g/525℃ |
|
Sieve analysis |
100% through 80 mesh |
USP36<786> |
|
Heavy metals: |
||
|
Total Heavy Metals |
≤10 mg/kg |
AAS |
|
Lead(Pb) |
≤2.0 mg/kg |
AAS |
|
Arsenic(As) |
≤1.0 mg/kg |
AAS |
|
Cadmium(Cd) |
≤1.0 mg/kg |
AAS |
|
Mercury(Hg) |
≤0.1 mg/kg |
AAS |
|
Microbiology(Non irradiated) |
||
|
Total Plate Count |
≤10000cfu/g |
AOAC |
|
Yeast & Mold |
≤1000cfu/g |
AOAC |
|
E.Coli |
Negative |
AOAC |
|
Salmonella |
Negative |
AOAC |
Manufacturing Flow Chart

HPLC Testing Methods
● Sample preparation:
Accurately weigh a sufficient amount of Andrographis Paniculata Extract Powder according to the required analytical sensitivity and dilute it with the appropriate solvent.
● HPLC instrument setup:
Start by setting up an HPLC instrument with an appropriate column, mobile phase, detection wavelength, and flow rate. The most common column used to analyze Andrographis Paniculata Sample Extract Powder is a reverse-phase column with a C18 stationary phase.
● Calibration:
To ensure the accuracy and reliability of the HPLC method, calibrate the instrument using standard solutions of andrographolide. This step is essential to determine the retention time and peak area of andrographolide in the sample.
● Injection and analysis:
Inject the prepared Andrographis Paniculata Extract Powder sample into the HPLC instrument and start the analysis. Observe the chromatogram of the sample. Look for andrographolide peak and quantify it using the calibration curve obtained earlier.
● Data analysis and interpretation:
Calculate the amount of andrographolide in the sample based on the peak area and the calibration curve. Report the results in the required units.
● Quality control:
Validate the method to ensure its suitability for analyzing Andrographis Paniculata Extract Powder. Perform system suitability tests to confirm the instrument's performance before sample analysis. The method should provide precise, accurate, and repeatable results.
TLC Identification

How to test Andrographis paniculata extract powder?
Detection of Andrographis paniculata extract powder can be done in many ways.Guanjie Biotech mainly includes appearance identification, chemical identification, content determination and bioactivity assay. The following are some of the commonly used methods:
1. Appearance
- Colour, odour and form:
Andrographis Paniculata Extract Powder is usually brownish-yellow or brown powder with special bitter taste and odour.
2. Determination of content
As mentioned earlier, HPLC can be used to accurately determine the content of Andrographolide. The specific steps are as follows:
● Sample preparation:
Our testing center takes an appropriate amount of Andrographis Paniculata Extract Powder and dissolves and filter with suitable solvent. Finally the sample solution was obtained.
●Chromatographic conditions:
We choose C18 chromatographic column. The mobile phase can be acetonitrile-water (containing 0.1% phosphoric acid) system, detection wavelength 220 nm.
● Sample Determination:
The Andrographis Paniculata Extract Powder sample was injected and the chromatogram was recorded. Calculate the content of Andrographolide.
3. Bioactivity assay
- In vitro bacterial inhibition assay:
The antibacterial activity of Andrographis paniculata leaf extract can be tested by agar diffusion method or microdilution method.
- Anti-inflammatory assay:
The inhibitory effect of the extract on inflammatory factors can be detected through cellular experiments or animal models.
4. Physical and chemical indexes
- Moisture determination:
Determine the water content in the extract by the dry weight loss method.
- Ash determination:
Burn a certain amount of Andrographis Paniculata Extract Powder to constant weight, and determine its ash content.
5. Microbiological limit checks
- Total Bacteria, Moulds and Yeasts:
Determine the microbial content of the Andrographis Paniculata Extract Powder sample by plate counting method or membrane filtration method.
Customer's Evaluation

Hive
Dietary Supplement Formulator

Kerry
Distributor

Herry
Functional Foods
Why Choose Guanjie Biotech?
Guanjie Biotech's operational policy for its Andrographis Paniculata Extract Powder is built on an integrated framework of Quality Assurance, Supply Chain Integrity, and Customer Partnership. This policy ensures that every batch of our extract, standardized to key bioactive compounds like Andrographolides, meets the highest standards of safety, efficacy, and regulatory compliance.

Quality and Purity Assurance:
Our foundational policy is a commitment to verifiable quality. This is executed through a stringent Standard Operating Procedure (SOP) that governs every stage, from the selection of raw Andrographis paniculata herb from qualified agricultural partners to the final packaging. We enforce a comprehensive specification sheet that includes potency (e.g., 10%, 20%, or 50% Andrographolides), heavy metals limits, pesticide residues, and microbiological purity. Every batch is validated by an independent, detailed Certificate of Analysis (CoA).

Sustainable & Traceable Sourcing:
We maintain a robust Raw Material Sourcing Policy. This mandates not only the botanical identity and geo-origin of the herb but also its sustainable cultivation. We prioritize partnerships with farms that adhere to Good Agricultural and Collection Practices (GACP). Our vertically integrated supply chain allows for full traceability from field to finished Andrographis Paniculata Extract Powder, mitigating risks of adulteration and ensuring a consistent, reliable supply for our business partners, even in times of market volatility.

Regulatory & Customer-Centric Compliance:
Recognizing the global nature of the supplement industry, our policy is designed to meet a wide array of international regulatory standards. Our manufacturing facility conforms to GMP (Good Manufacturing Practice) for dietary ingredients. The Andrographis Paniculata Extract Powder is produced to be compliant with frameworks. FDA's Dietary Supplement Health and Education Act (DSHEA) and relevant European Union regulations.
Factory&Team:

Certification

Package & Shipment

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