Pterostilbene Supplier

Pterostilbene Powder Supplier:

Guanjie Biotech is a pterostilbene supplier that offers high-quality pterostilbene powder. It is white powder. The purity of our pterostilbene bulk powder is rigorously tested using high-performance liquid chromatography (HPLC). We have two manufacturing facilities equipped with three separate production lines, allowing scalable and reliable production to meet diverse client needs. Our strict quality control and advanced manufacturing capabilities make our pterostilbene powder suitable for research, dietary supplements, and functional formulations. For more information or to request a Pterostilbene Powder sample, please contact us directly.

 

COA

Item	Specification	Result	Method
Basic Product Information
Country of Origin	China	Conform	/
Marker Compounds
Trans-Pterostilbene	>99.0%	99.66%	HPLC
Organoleptic Data
Appearance	Off-white fine powder	Conform
Taste	Characteristic	Conform
Physical Characteristics
Identification	Positive	Comform	IR, NMR
Particle Size (80 mesh)	NLT98% through 80Mesh	Conform	80Mesh Screen
Melting point	89.0℃-92.0℃	90.2℃	GB21781-2008T
Loss on Drying	<1.0%	0.65%	GB/T 14769-1993
Ash Content	<0.5%	0.22%	AOAC 942.05, 18th
Solubility	Soluble in ethanol, acetone, ether, etc.; insoluble in water.	Conform	Visual
Solvent Residue	Eur.Pharm.	Conform	GJ-QCS-1007
Heavy Metals
Total Heavy Metals	<10 ppm	Conform	USP <231>, method II
Arsenic(As)	<2.0 ppm	Conform	AOAC 986.15, 18th
Lead(Pb)	<2.0 ppm	Conform	AOAC 986.15, 18th
Cadmium(Cd)	<0.5 ppm	Conform	AOAC 986.15, 18th
Mercury(Hg)	<0.5 ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	<1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

 

Flow Chart:

See the Above PDF Files

 

Process Parameters And Procedures

1. First, before the feed preparation

● The column packing:

15kg of pure silica gel with petroleum ether mixed to a paste, paved cotton cheek plate to prevent leakage of silicone, then marinated in a silica gel column to enter, bottles, and topped with a layer of cheek plates with pure oil ethers red pillars three hours, until no bubbles until the liquid stream.

● Spices:

30kg Pterostilbene Powder, 2 times the amount of raw material dissolved in acetone. And then added with stirring silica 60kg, marinated raw spread in a stainless steel pan. Put into to ventilated place, stirring constantly to shake off the acetone. Dried and crushed through a 40 mesh screen to prepare the feed.

 

2. Second, the feeding:

Remove the upper cheek plate, and marinate raw materials slowly in the column. The edge went to the petroleum ether, stirring constantly, adding after the above, plus a layer of cheek plates with pure petroleum ether, punching pillars three hours until no bubbles until the flow of liquid, with a good solvent, ready for elution.

 

3. Third, the elution

● Pre-wash Miscellaneous:

Accurate with a good chloroform:

Acetone 7: 1 eluent to elute the beginning and start tracking TLC, pterostilbene supplier - our researchers collected separately, each stream into 5L, a flow rate of 30L / hr, parts of the collection flow color change light is also under no product instead chloroform: acetone 7: 1 elution have to track down a thin layer of the product, separate collection, transferred to the next step elution, the former cross-wash, pre-1-92 fractions extremely miscellaneous products.

● Cross before washing:

Continue with chloroform:

Acetone 7: 1 elution time tracking thin stream to 103 parts by former miscellaneous almost disappeared, collected separately, into the next step elution, that washes the middle fraction that is 93-103 a front cross pterostilbene.

● Wash the middle:

Continue with chloroform: acetone 7: 1 elution, TLC tracking appears to have 172 stream after miscellaneous parts, the separate collection, transferred to the next step elution, which cross-washed, 104-172 fractions i.e. for the middle of pterostilbene.

● Washed cross:

To chloroform: acetone 4:1 as eluent to track when a thin layer of the product fractions 181 spots almost disappeared, is collected separately from the cross, and is 173-181 fractions after cross pterostilbene.

 

4. Fourth, concentrate:

●Preparation

Check whether the device is normal.

Check the amount of eluent.

● Practice

Separated and concentrated using a rotary evaporator, the liquid level can not be above the surface of the water bath when the segments into the liquid, began to concentrate.

Open the cooling water system, a rotary evaporator to pass into the condensate into the night to close the vacuum valve, the material is slowly heated in a vacuum, and carefully observe the materials state.

Was heated under vacuum conditions, at any time in the eluate was evaporated solvent vapor generated is recovered after cooling.

The process temperature control below 55 ℃, the temperature too at the end, the evaporation rate is too slow, the end of the recovery vehicle.

Paragraphs concentrated to a small volume, which crystallized on standing, were collected each segment, before heteroaryl, anterior cruciate, and posterior cruciate dried sample test package. Middle recrystallization.

 

5. Five, recrystallization, decolorization

● Alcohol-water crystallization:

The middle of the collected and concentrated to dryness, weighed, 10 times the amount of pure ethanol is heated so that the entire dissolved, the Pterostilbene Powder product of 10% by weight of activated carbon, heated to reflux for 1 hour, and hot smoke into account, can not be removed thereof, the alcohol solution was allowed to cool, water was added dropwise, and stirring constantly so that a large number of crystallization, stop adding water into the refrigerator for 24 hours and filtered to give the product (content of more than 90%) drying into the next step.

● Bleaching:

Previous drying of the crystalline product, 10 times the amount of pure ethanol is heated so that the entire dissolved, the product of 10% by weight of activated carbon, heated to reflux for 1 hour and hot suction filtration, activated carbon, and insoluble matter was removed, the alcohol liquid cool, chloroform was added dropwise, stirring constantly, to make a large number of crystallization, stop adding water into the refrigerator for 24 hours and filtered to give the product (more than 98% content) drying packaging sample test.

 

The main equipment list

We are the pterostilbene supplier, this is the main equipment list.

name	Type no.	Quantity/Taiwan	For note
Stainless steel column chromatography	Ф30×180cm	6
Rotary evaporation instrument	20L	1	With water bath pot
Three by ultraviolet instrument		1
Plastic jugs	10L	20

 

Factory&Team：

 

Certification

 

Package & Shipment

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