Salvia Miltiorrhiza Extract Powder

Salvia Miltiorrhiza Extract Supplier:

Guanjie Biotech has focused on bulk Salvia Miltiorrhiza Extract powder for more than 20 years. Our products pass HALAL, ISO9001, KOSHER, and HACCP. If you need the third-party testing, we can provide you. The specifications of our bulk Salvia Miltiorrhiza Extract include the Tanshinone II assay with concentrations of 4%, 5%, 10%, 40%, 50%, 90%, and 98%. If you need customized, welcome to inquire: info@gybiotech.com.

Why Choose Guanjie Biotech?

● We operate independent factories and labs.
● We provide third-party testing services.
● We have been in this field for 20 years.
● We have strong collaborators, including Northwestern University and the Chinese Academy of Sciences Research Center.

 

COA

Item	Specification	Result	Method
Basic Product Information
Genus and Species	Salvia miltiorrhiza Bge.aaa	Conform	/
Part of the Plant	Root	Conform	/
Country of origin	China	Conform	/
Marker Compounds
Tanshinone IIA	>4.0%	4.05%	HPLC
Organoleptic Data
Appearance	Powder	Conform	NLS-QCS- 1008
Color	Brown red	Conform	GJ/T 5492-2008
Odor	Characteristic	Conform	GJ/T 5492-2008
Taste	Characteristic	Conform	GJ/T 5492-2008
Process Data
Method of Processing	Extraction	Conform	/
Solvent(s) Used	Ethanol & Water	Conform	/
Physical Characteristics
Particle Size (80 mesh)	>95.0%	Conform	GJ/T 5507-2008
Moisture	<5.0%	2.2%	GJ/T 14769- 1993
Ash Content	<5.0%	3.0%	AOAC 942.05, 18th
Solvent Residue	Eur. pharm	Conform	NLS-QCS- 1007
Heavy Metals
Total Heavy Metals	<10 ppm	Conform	USP <231>, method II
As	<2.0 ppm	Conform	AOAC 986. 15, 18th
Pb	<2.0 ppm	Conform	AOAC 986. 15, 18th
Hg	<0.5 ppm	Conform	AOAC 986. 15, 18th
Cd	<0.5 ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GJ/T5009. 19- 1996
DDT	<0.2ppm	Conform	GJ/T5009. 19- 1996
Microbiology
Total Plate Count	<1,000cfu/g	65cfu/g	AOAC 990. 12, 18th
Total Yeast & Mold	<100cfu/g	12cfu/g	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997. 11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

 

What Is the Chemical Structure of Salvia Miltiorrhiza Extract Powder?

Bulk Salvia Miltiorrhiza Extract Powder is a mixture of many ingredients. There is no single molecular or structural formula. The main components include tanshinone and salicylic acid.

Tanshinone is a class of fat-soluble components. It has a variety of structural types. Such as tanshinone I, tanshinone IIA, etc.; Tanshenolic acid is a class of water-soluble components. This includes salicylic acid A, salicylic acid B and so on. The chemical structure of these components is more complex. It contains several ring structures and functional groups.

The chemical stability of Salvia Miltiorrhiza Extract Powder is affected by environmental factors. Especially light and temperature. Tanshinones may be degraded when exposed to strong light or high temperatures. Whereas tansylic acid analogues may undergo hydrolysis under extreme pH conditions. Therefore, care needs to be taken to avoid unfavorable environmental conditions when storing and using danshen extracts to maintain the stability of their chemical composition.

 

What Are the Functions of Salvia Miltiorrhiza Extract?

1. Antioxidant

Tanshinone is in the fat-soluble constituents of Salvia divinorum. The total phenolic acids in the water-soluble constituents have strong anti-lipid peroxidation and free radical scavenging effects. This is the main component of the antioxidant effect.

Li et al. showed that the antioxidant activities of the four main components of Salvia miltiorrhiza were in the following order: cryptotanshinone＞tanshinone IIA＞dihydratanshinoneⅠ＞tanshinone I.

 

2. Anti-inflammatory

Bulk Salvia Miltiorrhiza Extract Powder can improve the tolerance threshold of sensitive skin and reduce skin discomfort such as redness and itching. It will improve skin comfort. The mechanism lies in the fact that both water-soluble and fat-soluble components of Salvia divinorum have certain antibacterial/anti-inflammatory activities.

The fat-soluble components of Salvia miltiorrhiza are mainly tanshinones. This has significant bacteriostatic effects on a wide range of bacteria including Staphylococcus, Bacillus, Escherichia coli, and Klebsiella pneumoniae.

 

Salvia Miltiorrhiza Extract Powder powder has anti-inflammatory and enhancement of body's immune regulation, in which tanshinone has an obvious anti-inflammatory effect. Tanshinone IIA is the main substance of tanshinone components, which exerts an anti-inflammatory effect by inhibiting the activation of the central pathway of the inflammatory response, NF-κB, and reducing the macrophage inflammatory mediator generation and release, inhibiting the release of various inflammatory factors.

Tanshinone can inhibit the growth of Propionibacterium acnes by lowering inflammatory factors such as IL-6, inhibiting the inflammatory response, and ultimately achieving the purpose of treating acne.

 

3. Whitening

A certain concentration of Salvia miltiorrhiza extract inhibits the proliferation of A375 cells (human malignant melanoma cells) and at the same time significantly inhibits intracellular tyrosinase activity. Salvia divinorum achieves its whitening effect by inhibiting the activity of tyrosinase. Tyrosinase is a key enzyme in the melanin synthesis process. Overactive tyrosinase can lead to pigmentation problems such as discoloration and dullness. Tanshinone in Salvia divinorum has a significant effect of inhibiting tyrosinase activity. This will reduce the production of melanin and achieve a whitening effect.

 

4. Improve microcirculation

Bulk Salvia Miltiorrhiza Extract Powder can improve microcirculation. Microcirculation refers to blood flow through tiny blood vessels, such as capillaries, tiny veins and tiny arteries, which play a vital role in maintaining the normal function of tissues and organs. When microcirculation is impeded, tissues are unable to receive sufficient oxygen and nutrients, which may lead to a range of health problems. Salvia promotes microcirculation through several mechanisms, positively impacting cardiovascular and systemic health.

 

• Improve microcirculation by dilating blood vessels.

The main active ingredients of Bulk Salvia Miltiorrhiza Extract Powder include tanshinone, salicylic acid, and other phenolic compounds. These components dilate blood vessels and increase their diameter. This decreases resistance to blood flow and promotes smoother blood flow through the tiny vessels. This vasodilatory effect helps to increase the blood supply to the tissues and enhances the delivery of oxygen and nutrients.

 

• Anticoagulant and antithrombotic properties.

Active ingredients inhibit platelet aggregation and prevent the formation of blood clots. Such as tanshinones. This is essential for improving microcirculation. This is because the formation of blood clots can block the microvessels, preventing blood from passing through smoothly. This can trigger tissue hypoxia and damage. By preventing the formation of blood clots, Salvia Miltiorrhiza Extract Powder ensures that the microvessels are clear and promotes the proper flow of blood through the microcirculation.

 

• Regulates blood lipid levels.

High blood lipids are one of the most important factors affecting microcirculation. Excessive blood lipids increase the viscosity of blood and slow down blood flow. Bulk Salvia Miltiorrhiza Extract Powder can regulate blood lipids. It lowers cholesterol and triglyceride levels, reduces the risk of atherosclerosis, and improves blood flow through the microvessels.

 

Is Salvia Miltiorrhiza Extract Suitable for Skin?

Suitable for most skin types. People with sensitive skin, acne, or eczema, and other skin problems. Similar ingredients to salvia extract include turmeric extract and ginkgo biloba extract. Turmeric extract also has antioxidant and anti-inflammatory properties. It may have some synergistic effects with salvia extract in skincare. Despite the multiple benefits of bulk Salvia Miltiorrhiza Extract Powder on the face, everyone's skin is characterized differently.

 

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