Bulk Vitamin K2

Bulk Vitamin K2 Supplier

Guanjie Biotech is a professional bulk Vitamin K2 supplier, providing high-quality Vitamin K2 MK-7 ingredients to global nutraceutical, food, and dietary supplement manufacturers. The CAS No. is 2124-57-4. We supply pure Vitamin K2 with content levels of 96%, 98%, and 99%, suitable for high-potency applications. In addition, several finished ingredient forms are offered, including powder (0.2%, 1%, 1.3%, 2%) with a light yellow to yellow appearance, oil solutions (0.2%, 1%, 1.3%, 2%) with light yellow to yellow oily liquids, and microencapsulated powder (0.2%, 1%, 1.3%, 2%) appearing white to pale yellow. Bulk vitamin K2 with stable quality, flexible specifications, and competitive pricing, Guanjie Biotech supports efficient product development and reliable supply for international markets. Welcome to enquire with us at info@gybiotech.com.

 

Why Choose Guanjie Biotech's Bulk Vitamin K2?

• Own Production Lines

Guanjie Biotech controls the entire manufacturing process with its dedicated production facilities, ensuring consistent quality and reliable supply.

• Certified Quality

Our Bulk Vitamin K2 Products are backed by internationally recognized certifications, including HALAL, HACCP, and KOSHER, providing assurance for global market compliance.

• High Purity & MK-7 Content

The Vitamin K2 offered features high purity with concentrated MK-7, delivering maximum efficacy in dietary supplements and fortified products.

• Green Fermentation Process

Produced through environmentally friendly fermentation without toxic or harmful solvents, ensuring a clean, safe, and sustainable ingredient.

• 100% All-Trans Form

Guanjie Biotech's Vitamin K2 is in the biologically active all-trans form, offering more stable properties and prolonged activity for superior functional benefits.

• Multiple Dosage Forms & Customization

Bulk Vitamin K2 is available in powder, oil, and microcapsule powders, with customizable options to meet diverse product formulation requirements and application needs.

 

COA:

Test Items		Specification	Result
Appearance		Light yellow oily	Conforms
Identification(HPLC)		The retention time of the major peak of the Sample solution corresponds to that of the Standard solution	Conforms
Composition	(Menaquinone-7)	≥2000 ppm	2324 ppm
Isomeric Purity	(cis-Menaquinone-7)	≤2%	Not Detected
Impurity	(Menaquinone-6)	≤200 ppm	41 ppm
Heavy Metals	Arsenic	≤2.0 μg/g	Conforms
	Lead	≤3.0 μg/g	Conforms
	Mercury	≤0.1 μg/g	Conforms
	Cadmium	≤1.0 μg/g	Conforms
Microbiological Limits	Total Aerobic microbial count	≤1000 CFU/g	Conforms
	Molds and Yeasts count	≤100 CFU/g	Conforms
	E. Coli	Absent	Not Detected
	Salmonella sp.	Absent	Not Detected
	Staphylococcus aureus	Absent	Not Detected

 

What Is Vitamin K2?

Vitamin K2, also known as menaquinone, is a fat-soluble vitamin essential for bone and cardiovascular health. It plays a crucial role in activating proteins that regulate calcium metabolism, helping direct calcium to bones and teeth while preventing its accumulation in arteries and soft tissues. Vitamin K2 exists in several forms, primarily MK-4 and MK-7, each with unique absorption and biological activity. Unlike Vitamin K1, which is abundant in leafy greens, Bulk Vitamin K2 is found in fermented foods, animal products, and supplements. Its growing recognition in nutraceuticals and functional foods makes it a key ingredient for health-focused product development.

 

What Is the Appearance of Bulk Vitamin K2?

Bulk Vitamin K2 can be provided in different formulations, each with distinctive visual and sensory characteristics. When a small sample is placed in a clean beaker or tray and observed under natural light, the vitamin K2 MK-7 bulk powder form appears as a pale yellow to white powder. The microencapsulated powder ranges from white to light yellow, reflecting its encapsulation process. The vitamin K2 MK-7 oil form is a clear liquid, varying from pale yellow to bright yellow. All Vitamin K2 preparations possess their characteristic odor, with no offsmells, ensuring product quality and consistency. The appearance of Bulk Vitamin K2 attributes are important indicator for purity, formulation type, and handling in both industrial and nutritional applications.

 

How is Vitamin K2 Produced?

Bulk Vitamin K2 is a fat-soluble vitamin widely recognized for its essential roles in bone and cardiovascular health. Producing high-quality Vitamin K2 for supplements or functional foods requires a precise, multi-step process to ensure purity, stability, and bioavailability. The production typically begins with microbial fermentation and progresses through extraction, filtration, concentration, and formulation, depending on the desired final product form, such as oil or powder.

Raw Materials Preparation

The production process of bulk vitamin K2 starts with selecting high-quality raw materials. Commonly used inputs include soybean powder, glucose, sugar, and pure water, which serve as nutrient sources and fermentation media. Soybeans provide essential proteins and lipids that support microbial growth, while glucose and sugar act as energy sources for the fermentation organisms. Ensuring the quality and consistency of these raw materials is critical, as impurities or variability can affect the fermentation efficiency and final Vitamin K2 yield.

Sterilization and Fermentation

Once prepared, the mixture undergoes sterilization to eliminate unwanted microorganisms and ensure a controlled environment for fermentation. Sterilization is typically achieved through heat treatment, which prevents contamination and promotes consistent microbial growth. After sterilization, the mixture is inoculated with Bacillus subtilis natto, a bacterial strain capable of producing Vitamin K2. Fermentation occurs under carefully controlled conditions of temperature, pH, and aeration to optimize Vitamin K2 synthesis. During this stage, the microorganisms metabolize the nutrients in the medium, producing Vitamin K2 as a secondary metabolite along with other microbial biomass.

Membrane Filtration and Concentration

Following fermentation, the mixture contains a combination of bacterial cells, fermentation broth, and bulk Vitamin K2. To isolate the vitamin, the solution undergoes membrane filtration, which separates microbial biomass and other particulates from the Vitamin K2-containing supernatant. The filtered solution is then concentrated using membrane concentration technology, which reduces the volume while preserving the bioactive compounds. This step ensures that the extract is rich in Vitamin K2 and minimizes losses during subsequent processing.

Extraction and Separation

The concentrated supernatant is subjected to extraction, where Vitamin K2 is separated from residual fermentation components. For formulations requiring oil, soybean oil can be added during extraction to improve solubility and stability. The extracted Vitamin K2, often referred to as the Vitamin K2 extract, is then purified further to remove impurities. This step is critical in achieving the high purity standards required for dietary supplements and nutraceutical applications.

Filtration, Drying, and Formulation

After extraction, the solution undergoes filtration and filling for oil-based products. For powder or microencapsulated formulations, the extract is combined with excipients, then subjected to drying processes to produce a stable Vitamin K2 bulk powder. Drying can involve techniques such as spray drying or freeze-drying, which help preserve the vitamin's activity while producing a free-flowing powder suitable for blending or encapsulation.

Packaging and Final Products

The final Vitamin K2 products can be categorized as oil or powder forms, depending on the formulation requirements. Oil-based Vitamin K2 is clear, ranging from pale yellow to bright yellow, and is commonly used in softgels or liquid supplements. Powdered forms, including microencapsulated powders, allow for more flexible applications in tablets, capsules, or functional foods. The final products are then subpackaged and labeled, ready for distribution.

 

By combining TLC for qualitative analysis and HPLC for quantitative validation, Guanjie Biotech ensures that every batch of Vitamin K2 meets high-quality standards. These methods not only confirm the identity and purity of the product but also guarantee consistency for industrial applications and dietary supplement formulations. Clients can trust that Guanjie Biotech's bulk bulk Vitamin K2 is thoroughly tested, compliant with international standards, and ready for safe and effective use in health-related products.

 

Company Advantages:

 

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