Cas 81 25 4

Cholic acid powder CAS 81 25 4 is a crystalline substance that belongs to the class of bile acids. It is a steroidal compound derived from cholesterol metabolism in the liver. Chemically, it is known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid. It plays a crucial role in the digestion and absorption of dietary fats and fat-soluble vitamins. Additionally, cholic acid contributes to the regulation of lipid metabolism and cholesterol homeostasis in the body. Guanjie Biotech is a Cholic Acid supplier, which has focused on CAS 81 25 4 for more than 10 years. Own R&D center and factories, with high quality. If interested, please send an email to enquiry at info@gybiotech.com.

 

● High-Quality Product:

Our Cholic Acid Powder CAS 81 25 4 is sourced from FDA-certified factories. We prioritize strict quality control measures throughout the manufacturing process to ensure the highest standards of purity and potency.

● Customized Products: We offer support for customized Cholic Acid tailored to meet your unique needs. Our team can work with you to develop the desired product specifications.

● High Quality Control:

Quality is our top priority. We implement comprehensive quality control protocols to ensure consistent and reliable product performance. Our Cholic Acid Powder undergoes rigorous testing to comply with industry standards and regulations.

●Proven Transportation Channels:

We have established reliable transportation channels to ensure the timely delivery of your orders. Our logistics partners are experienced in handling sensitive products, ensuring safe and efficient delivery to your desired location.

● Excellent Customer Service:

Our dedicated customer service team is committed to providing exceptional support. We are available to address any inquiries, discuss customization options, and assist you throughout the ordering process. Your satisfaction is our ultimate goal.

 

Items	Specification	Result
Appearance	A white powder	White powder
Identification (by HPLC)	The retention time of the principal peak in the test solution HPLC chromatogram obtained under the conditions described in the section 'Related substances to the retention time of the principal peak in the standard solution.	Pass
Melting point	197℃-202℃	197.7℃-198.8℃
Loss on drying	≤1.0%	0.35%
Sulphated ash	≤0.20%	0.03%
Related substance(HPLC)	≥95%(Purity)	97.41%
	≤2.0%(Single highestimpurity)	0.98%
	≤5.0%(Totalimpurities)	2.59%
Assay (by titration)	98.0%~101.0%	98.7%
Conclusion	Confirm

 

The molecular formula of cholic acid powder is C24H40O5, and it has a molecular weight of approximately 408.57 g/mol. And the CAS NO. IS CAS 81 25 4. Structurally, it consists of a four-ring steroid backbone with hydroxyl groups at positions 3, 7, and 12, along with a carboxylic acid group at position 24.

 

● Chemical Synthesis:

Cholic acid cas 81 25 4 can be synthesized in laboratories using chemical reactions. This method involves starting materials such as cholesterol and various chemical reagents that undergo several steps, including oxidation, reduction, and hydrolysis, to obtain cholic acid.

● Microbial Fermentation:

In some cases, microbial fermentation processes may also be employed to produce cholic acid. This approach utilizes genetically modified microorganisms capable of biosynthesizing cholic acid.

 

1.Standard

NLT 99%-101% percent
2. Experimental method
● Sample preparation: Weigh the sample 0.350g (g; g) (moisture content %), dissolve with 50ml ethanol, add 0.2ml phenolphthalein indicator solution, add 50ml water. Titrate with mol/L sodium hydroxide titrant until pink. Consume sodium hydroxide titrant ml; ml.
● Titration blank without specimen under the same conditions Consumption of sodium hydroxide titrant ml.

● Experimental conditions
① titration solution: 0.1 mol / L sodium hydroxide titration solution
② Relative amount: 0.1mol / L sodium hydroxide titration solution 1ml = 39.258mgC24H40O4

Calculation formula

w: content of sample CAS 81 25 4 CDCA, %;
c: concentration of sodium hydroxide titration solution, mol/L;
v1: volume of sodium hydroxide titrant consumed for titrating the specimen, ml;
v0: volume of sodium hydroxide titrant consumed for titration of blank, ml;
m: mass of weighed specimen, g;
w0: moisture content of the sample

 

● Bovine (Cattle) Gallbladder: Bile is collected from the gallbladders of slaughtered cattle. The bile undergoes a series of processes like extraction, purification, and crystallization to isolate cholic acid.

● Porcine (Pigs) Gallbladder: Similar to bovine gallbladder extraction, porcine gallbladders are utilized to extract cholic acid.

 

1. Food Industry:

● Regulation and Safety:

It is subject to regulatory guidelines as a food additive. Its safety and permissible use are strictly regulated to ensure consumer protection.

● Flavor Enhancer:

CAS 81 25 4 can act as a flavor enhancer in certain food products. It interacts with taste receptors and enhances the perception of specific flavors.

● Emulsifier and Stabilizer:

It helps create stable emulsions in various food products. It improves the texture and stability of emulsions, such as dressings, sauces, and creamy desserts.

 

2. Biochemical Research:

Cholic acid powder cas 81 25 4 is widely used in biochemical research. Its functions include:

● Lipid Metabolism:

Cholic acid is involved in the regulation of lipid metabolism and cholesterol homeostasis. Research focuses on understanding its role in lipid absorption, transportation, and synthesis.

● Bile Acid Biology:

It contributes to the study of bile acid composition, synthesis, and enterohepatic circulation. This research helps unravel the mechanisms underlying bile acid-mediated physiological processes.

● Signaling Pathways:

Cholic acid is explored for its effects on cellular signaling pathways, including nuclear receptors such as farnesoid X receptor (FXR) and other signaling molecules involved in metabolic regulation.

 

3. Cell Culture Applications:

It finds application in cell culture research and techniques. Its functions include:

● Cell Culture Media:

CAS 81 25 4 is used as a supplement in cell culture media, particularly in studies involving hepatocytes. It provides essential components required for the growth and function of liver cells.

● Hepatocyte Support:

Cholic acid supports the growth, maintenance, and functionality of hepatocytes in vitro. It ensures accurate representation of liver cell behavior and facilitates drug metabolism and toxicity studies.

 

4. Cosmetic Industry:

Some key functions include:

● Emulsifying Properties:

It acts as an emulsifier, enabling the mixing of oil and water-based ingredients in cosmetic products. This property allows for stable and uniform formulations.

● Moisturization:

It contributes to hydration and moisturization of the skin and hair. It helps retain moisture and prevents dryness, making it beneficial in skincare and hair care products.

● Anti-Aging Potential:

CAS 81 25 4 is explored for its potential role in anti-aging formulations. It promotes collagen synthesis and improves skin elasticity, contributing to reducing the appearance of wrinkles and fine lines.

With these properties, cholic acid powder finds applications in various cosmetic products, including creams, lotions, shampoos, and anti-aging formulations.

 

When using cholic acid powder CAS 81 25 4, it is essential to follow proper usage guidelines and adhere to regulations specific to each application area. Consulting with healthcare professionals, regulatory authorities, or experts in the field is advisable to ensure safe and effective use.

 

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