Genistein Powder

Genistein Powder Supplier:

Guanjie Biotech has been a bulk genistein powder supplier for 20 years. We focus on high-quality products and strict quality control. Test methods and factory reports are available. We support custom processing and sample customization. Genistein powder is a polyphenol compound that belongs to the isoflavone family. It is mainly found in legumes, especially in Sophora japonica. It is a light yellow crystalline powder. It is soluble in common organic solvents and dilute alkali solutions, where it is yellow. But genistein is almost insoluble in water. We mainly use alcohol extraction, purification, and crystallization processes during production. High-quality genistein powder with a competitive price. If you are interested, please contact us at info@gybiotech.com.

 

 

COA

Item	Specifications	Results
Appearance	Light yellow	Conforms
Content	>98.0%	98.3%
Melting point	297-299℃	298.8℃
Loss on drying(%)	≤1.0	0.18
Ash on Residual(%)	≤0.5	0.05
Heavy metals(ppm)	≤20	<20
Hg	≤0.1	Conforms
Pb	≤2.0	Conforms
As	≤1.0	Conforms
Cd	≤1.0	Conforms
Total Plate Count	≤1000cfu/g	Conforms
Yeast & Molds	≤100cfu/g	Conforms
E. Coli	Negative	Negative
Salmonella	Negative	Negative

 

What Does Genistein Powder Do?

● Anti-osteoporosis

Genistein powder is a kind of "phytoestrogen". It can promote osteoblast proliferation, differentiation and mineralized bone formation, and also inhibit the osteoclast bone resorption process, and there are various anti-osteoporosis molecular mechanisms.

Genistein, as a safe and effective "phytoestrogen", can selectively bind ER in vivo and play a role in preventing osteoporosis. In addition, genistein is abundant in its source, simple in the extraction process, conducive to industrial production, and less toxic side effects in long-term treatment, which has good prospects for clinical application.
 

Genistein's anti-osteoporosis effect involves promoting osteoblast proliferation, differentiation and bone formation, and inhibiting osteoclast proliferation, differentiation and bone resorption. In addition, Genistein Powder acts as a "phytoestrogen". It binds with estrogen receptors (es- trogen receptors, ER) in vivo to produce a regulatory effect. It is an ideal natural compound with selective estrogen receptor modulating activity.

 

Genistein powder can exert its inhibitory effect on osteoclast bone resorption through the NF-κB pathway. In addition, genistein mediates the intracellular calcium signaling pathway and inhibits protein kinase and tyrosine kinase. Thus, it induces osteoclast apoptosis, which in turn inhibits bone resorption. It also reduces osteoclast formation by inhibiting DNA topoisomerase II activity.

Osteoporosis is a disease with increasing morbidity and disability, so new anti-osteoporosis drugs have been a hot spot of research at home and abroad. Genistein is a safe and effective "phytoestrogen". It can selectively bind ER in the body and play a role in preventing osteoporosis. In addition, genistein is rich in sources, simple in extraction process, favorable for industrial production, and has less toxic side effects during long-term treatment, so it has a better prospect for clinical application.

 

● Estrogen-like effects of genistein

Genistein is structurally similar to endogenous estrogen, especially 17β-estradiol. Because of this similarity, genistein can show estrogen-like activity in the body.

Humans have two main types of estrogen receptors. These are estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). These receptors are found in many tissues. They are present not only in the reproductive system but also in bone-related cells.

Estrogen receptors exist in osteoblasts, osteoclasts, and bone marrow stromal cells. ERα is mainly expressed in osteoblasts. ERβ is found in osteoclasts and other bone tissues.

Research shows that genistein powder has a stronger affinity for ERβ than ERα. However, studies suggest that ERα may play a major role in the bone-protective effects of genistein.

Phytoestrogens also have bidirectional regulatory effects. Under different conditions, they may act like estrogen or show anti-estrogen activity. Lower concentrations may stimulate activity, while higher concentrations may inhibit activity. This regulatory effect makes genistein an interesting compound for further study.

 

● Bacterial inhibition

Genistein powder bulk also shows antibacterial activity. Its antibacterial effects may involve several mechanisms.

It may disrupt the integrity of bacterial cell walls and cell membranes. Damage to these structures can affect bacterial survival. Genistein may also interfere with the TCA cycle pathway and protein synthesis in bacteria.

Studies suggest that these actions contribute to bacterial inhibition. Research findings are consistent with previous studies on antibacterial mechanisms.

In addition to antibacterial effects, genistein also has antioxidant properties. Because of these combined functions, genistein powder may have potential applications in the food and nutrition industries.

From a nutritional perspective, genistein bulk powder may serve as a valuable food ingredient. Its dual antioxidant and antibacterial functions create promising opportunities for future use.

 

What Is Genistein Powder Used For?

Genistein powder is widely used in pharmaceuticals, health products, and cosmetic applications. It is also popular in many international markets, including Europe, the United States, India, and Asian countries.

● Golden Turn Stop Capsules

Golden Turn Stop Capsules are made using advanced production technology. Natural isoflavone extract is used as the main raw material. Genistein Powder is the key active ingredient in this product.

Studies and functional tests suggest that genistein powder may help support the inhibition of tumor growth and metastasis. It has gained attention because of its specific mechanism and plant-based source. Genistein is also valued for its low toxicity profile and natural properties.

Compared with some traditional chemical or herbal products, Genistein-based formulations have attracted interest in related research fields. These products have shown strong market potential. Since launch, they have sold well in China and gained attention from customers in Japan, the United States, Canada, Hong Kong, and Southeast Asia.

 

● I-cool Menopause Bone Health Chewable Tablets

The main ingredients in this product include Vitamin D, Calcium, and Genistein. These ingredients are used to support bone growth and development.

Genistein Powder is often added to bone health products for women, especially during menopause. It may help maintain bone strength and support overall bone health. Combined with calcium and Vitamin D, it can help reduce the risk of bone weakness and support healthy bones.

 

Our factory:

There are two factories both in Baoji city and Shangluo City, Guanjie factories covers an area of 7000㎡, including GMP standard workshop of 2000㎡.

 

Product Qualification

Genistein Bulk Powder is produced in a clean working environment and every step is conducted by highly qualified professionals. Both the production processes of manufacture and the product itself meet all international standards. And if you need our testing report, we can provide you.

 

Testing Center:

Both the production processes of manufacture and the product itself meet all international standards. And if you need our testing report, we can provide you.

 

Certification

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

 

 

Package&Warehouse:

Shipment:

DHL, FEDEX, Sea freight,Air freight you can choose.

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