Liposomal Coenzyme Q10 CoQ10

Liposomal CoQ10 Supplier

Guanjie Biotech is a professional Liposomal Coenzyme Q10 CoQ10 supplier in the global nutraceutical and functional food industries. We provide high-quality Liposomal Coenzyme Q10 CoQ10 powder manufactured with advanced liposome encapsulation technology. It is yellow powder with excellent dispersibility and stability. Its particle size specification is 80 mesh, with ≥90% passing rate, ensuring uniform texture and easy formulation processing. One of the major advantages of this Liposomal CoQ10 powder is its excellent water solubility, which allows convenient application in solid beverages, capsules, tablets, sachets, and other functional products. Through phospholipid encapsulation technology, the product offers improved bioavailability, enhanced absorption efficiency, and better protection of the active ingredient during storage and application. High-quality Liposomal Coenzyme Q10 CoQ10 and a competitive price. Welcome to enquire with us at info@gybiotech.com.

COA:

TEST ITEM		SPECIFICATION		RESULT
Description		Yellow powder		Conform
Particle size (80 mesh)		≥90%		Conform
Loss on drying		≤5.0%		2.2%
Bulk Density		Measured value		320g/L
Tapped Density		Measured value		510g/L
Heavy Metals	Arsenic (As) Lead (Pb) Mercury (Hg) Cadmium (Cd)		<2.0ppm <3.0ppm <0.3ppm <0.3ppm	Conform
				Conform
				Conform
				Conform
	Total plate count	≤1000cfu/g		70cfu/g
Microbiological	Total molds and yeasts	≤100cfu/g		15cfu/g
	Coliforms	≤10MPN/g		Conform
	E.Coli	Negative/25g		Negative
	Salmonella	Negative/25g		Negative
	Staphylococcvs	Negative/25g		Negative
Assay	Q10 Coenzyme Q10	70.0%±5%		70.5%
Conclusion		Meet the in-house standard

 

How is Liposomal Coenzyme Q10 Produced?

The production flow of fat-soluble Liposomal Coenzyme Q10 CoQ10 is a highly controlled process designed to improve the stability, dispersibility, and bioavailability of active compounds. Liposomal technology encapsulates fat-soluble nutrients within phospholipid bilayers, helping protect sensitive ingredients from oxidation and improving their absorption in functional foods, dietary supplements, beverages, and pharmaceutical formulations. As a professional Liposomal Coenzyme Q10 manufacturer and supplier, Guanjie Biotech provides a wide range of liposomal and phospholipid-based ingredients for global customers. We use the spray-dried and freeze-dried method to produce Liposomal Coenzyme Q10 CoQ10.

Spray-dried Method

Raw Materials (Sampling, Testing, Release)

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Film Forming (Phospholipids and Active Ingredients dissolved in Ethanol, concentrated into Films)

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Hydration in Purified Water

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Shearing at High Speed (Shearing the liposome solution to ≦500nm)

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1)High Pressure Homogenization    2)Ultrasonic Homogenization

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Bactericidal via Filtration (Sterilization by filtering through 0.22μm membrane)

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Spray Drying

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Sampling and Testing

↓

Packing and Storage

Freeze -dried Method

Lecithin, Gum Arabic, Ethanol, Purified water

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Homogeneous emulsion

↓

High-pressure homogenization

↓ →Coenzyme Q10

Encapsulated drug loading

↓

Freeze-Drying

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Grinding, Sieving, and mixing

↓

Liposomal Coenzyme Q10

↓

QA/QC

↓

Approve release

 

What Is The Water Solubility Of Liposomal Coenzyme Q10?

The water solubility characteristics of Liposomal Coenzyme Q10 CoQ10 can be detailed from the perspective of its unique formulation process. When 1 gram of the liposomal coenzyme Q10 sample is added to 100 ml of water, the formulation achieves complete and stable dispersion. Unlike conventional coenzyme Q10 (ordinary CoQ10 is almost insoluble in water due to its high lipophilicity), liposome encapsulation technology encapsulates coenzyme Q10 molecules within tiny vesicles composed of a phospholipid bilayer. This significantly improves its performance in an aqueous environment.

After mixing at the stated 1:100 (g:mL) ratio, liposomal coenzyme Q10 does not exhibit precipitation, aggregation, or floating oil films-no "impurities." Instead, the system spontaneously forms a clear, transparent liquid with a characteristic bright yellow color. This bright yellow color originates directly from the natural pigment properties of coenzyme Q10 itself, while the uniform dispersion is attributed to the colloidal stabilizing effect brought about by the nanoscale particle size of liposomes (typically less than 200 nm). Because light can pass through these tiny vesicles without significant scattering, the liquid appears clear and transparent. This characteristic not only directly demonstrates the success of liposome encapsulation and its effective improvement in the apparent water solubility of Liposomal Coenzyme Q10 CoQ10, but also signifies that the formulation possesses good physical stability. This facilitates the development of dosage forms such as oral liquids or functional beverages, thereby enhancing the absorption and utilization rate of the active ingredient in the body.

 

Accelerated Stability Study Data

Product Name: Liposomal Coenzyme Q10 Conditions: 25°C ± 2°C RH: 65% ± 5% Batch No.: GJ17-240101

Item	Specification	0	1	2	3	6
Appearance	Yellow Powder	Conforms	Conforms	Conforms	Conforms	Conforms
Loss on Drying	≤10.0%	4.51%	4.66%	4.68%	4.75%	5.42%
Assay (HPLC)	10-20%	15.74%	15.26%	15.19%	15.08%	14.96%
Conclusion	--	--	Conforms	Conforms	Conforms	Conforms
Test Date	--	2024.01.05	2024.02.05	2024.03.05	2024.04.05	2024.07.05

 

Batch No.: GJ17-240102

Item	Specification	0	1	2	3	6
Appearance	Yellow Powder	Conforms	Conforms	Conforms	Conforms	Conforms
Loss on Drying	≤10.0%	4.24%	4.56%	4.67%	5.12%	5.94%
Assay (HPLC)	10-20%	16.08%	16.10%	15.83%	15.59%	15.22%
Conclusion	--	--	Conforms	Conforms	Conforms	Conforms
Test Date	--	2024.01.06	2024.02.06	2024.03.06	2024.04.06	2024.07.06

Batch No.: GJ17-240103

Item	Specification	0	1	2	3	6
Appearance	Yellow Powder	Conforms	Conforms	Conforms	Conforms	Conforms
Loss on Drying	≤10.0%	4.08%	4.33%	4.95%	5.05%	6.03%
Assay (HPLC)	10-20%	17.11%	16.46%	16.88%	16.01%	16.12%
Conclusion	--	--	Conforms	Conforms	Conforms	Conforms
Test Date	--	2024.01.07	2024.02.07	2024.03.07	2024.04.07	2024.07.07

What are the advantages of Liposomal Coenzyme Q10?

Liposomal Coenzyme Q10 combines advanced liposome encapsulation technology with the biological benefits of Coenzyme Q10, helping improve ingredient stability, absorption efficiency, and formulation compatibility. Compared with conventional CoQ10 powder, Liposomal Coenzyme Q10 CoQ10 offers significant technical advantages in delivery performance and application flexibility. As the demand for high-bioavailability nutraceutical ingredients continues to grow, liposomal CoQ10 has become increasingly popular in dietary supplements, functional beverages, soft gels, and anti-aging formulations.

Enhanced Bioavailability

One of the most important advantages of Liposomal Coenzyme Q10 CoQ10 is its improved bioavailability. Traditional CoQ10 is fat-soluble and has relatively poor water dispersibility, which may limit absorption in the human body. Liposomal technology encapsulates CoQ10 within phospholipid bilayers, helping transport the active ingredient more efficiently through the digestive system. Laboratory validation studies have shown that liposomal encapsulation can significantly increase the absorption rate of CoQ10. This allows the body to utilize the active ingredient more effectively while reducing ingredient waste.

High Encapsulation Efficiency

Liposomal CoQ10 features high encapsulation efficiency, which helps maximize active ingredient delivery. Through optimized phospholipid formulation and advanced processing technology, a larger proportion of CoQ10 can be successfully enclosed within the liposome structure. This protective system helps shield the active ingredient from oxidation, environmental stress, and degradation during storage and digestion. High encapsulation efficiency also contributes to better product consistency and more reliable performance in finished formulations.

TEM Electron Microscopy Verification

The authenticity and structural integrity of Liposomal Coenzyme Q10 CoQ10 can be directly verified through Transmission Electron Microscopy (TEM) imaging. TEM analysis provides clear visualization of the spherical liposomal ubiquinol CoQ10 vesicles and confirms the successful formation of the encapsulation system. This analytical verification demonstrates that the product contains true liposome structures rather than simple emulsions or physical mixtures. TEM imaging also supports quality control and helps manufacturers maintain stable production standards.

Nanoscale Particle Size Below 100nm

Another major technical advantage of Liposomal Coenzyme Q10 CoQ10 is the extremely small particle size of the liposomes. Advanced homogenization technologies, including high-pressure homogenization and ultrasonic treatment, help control particle sizes below 100 nanometers. Nanoscale particles provide a larger surface area and better dispersion characteristics, which may improve ingredient absorption and formulation stability. Smaller particle size also contributes to a smoother appearance and improved compatibility in liquid applications such as beverages and oral solutions.

Versatile Applications and Excellent Stability

Liposomal Coenzyme Q10 CoQ10 offers excellent stability and dispersibility, making it suitable for a wide range of applications. The phospholipid encapsulation system helps improve resistance to oxidation and environmental degradation. At the same time, the enhanced dispersibility allows easier incorporation into Liposomal Coenzyme Q10 powders, Liposomal Coenzyme Q10 capsules, tablets, functional drinks, and nutritional formulations. Good stability during processing and storage helps maintain product quality and extends shelf life. These characteristics make liposomal CoQ10 ubiquinol an attractive ingredient for modern health product development. As a Liposomal Coenzyme Q10 supplier, we provide high-quality Liposomal Coenzyme Q10 powder at a competitive price.

 

Company Advantages:

 

Certification

 

Package & Shipment

 

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