3 3 Diindolylmethane Powder

3 3 Diindolylmethane Powder supplier

Guanjie Biotech has focused on 3 3 Diindolylmethane Powder for many years. We are a bulk 3 3 Diindolylmethane supplier. With a sound enterprise quality assurance system, Guanjie Biotech implements the strict quality control standards. We are a professional team to produce, research and sell on (DIM) DIM. We can provide you with high-quality 3 3 Diindolylmethane Powder products at the best price. As a professional pure DIM powder supplier, Guanjie Biotech is your best choice. Our clients are from all over the world, and we get high praise from them.

What Are the 3 3 Diindolylmethane Powder Advantages?

The 3 3 diindolylmethane bulk powder developed by our company has the following advantages:

● Ash content<0.5%, Specification requirement 1%

● Content: 99%

● Appearance: Pure white. White to pink for other families on the market.

● Moisture: 0.5%.  

● Drying temperature: 55-60 ℃

● Storage: Store in a cool & dry place, Keep away from strong light and heat under 8°C.

 

 

Why Choose Guanjie Biotech?

Guanjie Biotech is a bulk 3 3 Diindolylmethane powder manufacturer. It is a pure white colour: lowest solvent residue, highest purity. There are professional researchers from the Northwestern University laboratory and the Chinese Academy of Sciences laboratory. They have engaged in Chemical manufacturing for many years to promise our quality. And if you need 3 3 Diindolylmethane Powder third-party testing, please submit your requirement in the form below. Our products have received a lot of praise from the USA, Canada, England and other countries.

 

COA

Items	Specifications	Result	Test Method
Appearance	Off-white to white crystalline powder	Conform	Visual
Odor, Taste	Characteristic	Conform	Sensory
Particle Size	98% pass 80mesh	Conform	GB/T 5507-2008
Content	≥99.0%	99.26%	HPLC
Residue on ignition	≤1.0%	0.22%	GB/T 9741-2008
Loss on drying	≤1.0%	0.51%	GB 5009.3-2016
Melting Point	165.0℃~169℃	167℃	GB/T 21781-2008
Heavy Metals	≤10 ppm	Conform	GB 5009.74-2014
Pb	≤2 ppm	Conform	GB 5009.12-2017
As	≤2 ppm	Conform	GB/T 5009.11-2014
Solvent Residue	Methanol≤3000ppm	Conform	GB 5009.262-2016
Total Plate Count	≤1000cfu/g	Conform	GB 4789.2－2016
Total Yeast & Mold	≤100 cfu/g	Conform	GB 4789.15－2016
E. Coli	Negative	Negative	GB 4789.38-2012
Salmonella	Negative	Negative	GB 4789.31-2016
Staphylococcus aureus	Negative	Negative	GB 4789.10-2016

 

Stability Studies

Sample:	3,3'-Methylenebisindole	Batch	20181125
Tempera:	5℃±2℃	Humidity	60%±5%
Item	Standard	0 Month	3 Month	6 Month	9 Month	12 Month
Appearance	off-white light yellow powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder
Assay	3,3'Methylenebisindole≥99%	99.45%	99.45%	99.45%	99.43%	99.40%
Loss on Drying	≤1.0%	0.45	0.47	0.47	0.51	0.55

 

Item	Standard	15 Month	18 Month	21 Month	24 Month	27 Month
Appearance	off-white light yellow powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder	Off-white to light yellow Powder
Assay	3,3'Methylenebisindole≥99%	99.40%	99.35%	99.20%	99.13%	98.89%
Loss on Drying	≤1.0%	0.58	0.68	0.68	0.69	0.75

 

Conclusion:

The test starts from Nov. 25, 2018, to. Nov. 24, 2020. After 3 months, 6months, 9months, 12months,15months, 18months, 21months, 24months,27months, compared with the result and found that the product is stable. It was confirmed that the expiry time is 2 years.

 

HPLC Test for Diindolylmethane

 

How is 3,3-dindolylmethane powder produced? 

Diindolylmethane (DIM), particularly the 3,3'-isomer with CAS number 1968-05-4, is typically synthesised through acid-catalysed reactions. The core process involves the condensation of indole with carbonyl sources, most commonly formaldehyde or aldehydes, to create the methane bridge that links two indole rings

For a bulk 3 3 Diindolylmethane Powder supplier like Guanjie Biotech, the choice of 3 3 Diindolylmethane Powder synthesis method involves balancing several factors beyond just the reaction yield.

Process Efficiency:

For large-scale 3 3 Diindolylmethane Powder production, continuous flow processes represent a significant advancement over traditional batch methods. In a batch process, reactants are combined in a single vessel and processed through a sequence of steps. This is often slower and can lead to inconsistencies between one batch and the next.

In contrast, a continuous flow system, such as one utilising a fixed-bed reactor with a specialised catalyst like a modified Hβ zeolite, operates by steadily pumping reactants through a reaction zone. This method offers several distinct advantages for industrial production:

• Easier Reaction Control:

Parameters like temperature and pressure can be maintained at optimal levels with high precision throughout the operation, leading to more consistent and predictable outcomes.

• Higher Throughput:

Because the reaction is ongoing, these systems can produce a much larger volume of product over the same period compared to a batch reactor of a similar size. This directly translates to increased production capacity.

• Stable Product Quality:

The consistent reaction environment minimizes variations, ensuring that the 3 3 Diindolylmethane Powder product from the beginning, middle, and end of a production run is of uniform quality. This reliability is crucial for meeting stringent industrial specifications.

Environmental Impact and Cost-Effectiveness

The principles of green chemistry are now central to modern chemical development, driving innovations that reduce environmental footprint and lower operational costs. Two major areas of focus are solvent and catalyst selection.

Historically, many industrial processes 3 3 Diindolylmethane Powder relied on large quantities of organic solvents, which can be toxic, volatile, and difficult to dispose of safely. A major trend is to replace these with greener alternatives, with water being the ideal choice where possible. Using water as a solvent dramatically reduces pollution hazards, waste generation, and the cost associated with solvent purchase and recovery.

Similarly, the shift from traditional liquid acid catalysts, which are often corrosive, difficult to handle, and generate significant waste, to solid acid catalysts is a critical improvement. Catalysts like the modified Hβ zeolite are heterogeneous, meaning they are in a different physical state (solid) than the reactants (liquid or solution). This allows for easy separation of the catalyst from the product mixture through simple filtration. Furthermore, many solid catalysts can be regenerated and reused multiple times, which reduces both 3 3 Diindolylmethane Powder material costs and the environmental burden of waste disposal.

Ensuring Final Product Purity

Regardless of how efficient or green a synthesis is, the final step is always purification to isolate the desired compound in a highly pure form. For 3 3 Diindolylmethane Powder, crystallisation is the most common and effective technique. This process involves dissolving the crude product in a warm solvent, such as toluene or a mixture of aqueous ethanol, and then carefully cooling the solution. As the solution cools, the solubility of the product decreases, causing it to slowly form pure, solid crystals. Impurities, which have different solubilities, remain dissolved in the liquid. The resulting crystals are then collected by filtration and dried, yielding the final high-purity 3 3 Diindolylmethane Powder product as a solid. This final purification is essential to ensure the product's efficacy, stability, and suitability for its intended application.

 

Our factory:

There are two factories both in Baoji city and Shangluo City. Guanjie Biotech factories covers an area of 7000㎡, including GMP standard workshop of 2000㎡.

 

Product Qualification

3 3 Diindolylmethane Powder is produced in a clean working environment and every step of the process is conducted by highly qualified professionals.

 

Testing Center:

Both the production processes of manufacture and the product itself meet all international standards. And if you need our testing report, we can provide you.

 

Certification

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

 

Package&Warehouse:

● Package: 1kg/Al.foil bag with transparent plastic bags inside

25kg/Paper drum with black plastic bag inside

 

Shipment:

DHL, Sea freight, FEDEX, you can choose.

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