Micronized Resveratrol Powder

Micronized Resveratrol Powder Supplier

Guanjie Biotech is a micronized resveratrol powder supplier, which has developed an advanced micronization process for resveratrol, enabling particle sizes to reach D50 <3 µm. This is achieved using a high-frequency vibration milling system, originally applied in precision industries, which allows for efficient particle size reduction while maintaining material integrity. Most high-purity botanical actives can be micronized effectively; for example, resveratrol can typically reach D90 <5 µm. However, during particle size analysis, electrostatic interactions may cause fine particles to agglomerate, affecting measurement accuracy. To ensure reliable characterization, Guanjie Biotech complements standard particle size testing with electron microscopy, providing a more precise evaluation of particle distribution and confirming the effectiveness of the micronization process for high-performance applications in nutraceutical and pharmaceutical formulations.

Resveratrol powder is derived from the roots of Polygonum cuspidatum using specialized extraction and purification techniques to obtain a high-quality extract. Micronized resveratrol powder is a white to off-white fine powder with a characteristic taste and mild odor, and it is soluble in water and ethanol. For optimal stability, Polygonum Cuspidatum Extract resveratrol powder should be stored in a cool, dry, and dark environment in a tightly sealed container or drum. Multiple specifications are available, and customized formulations can be provided to meet specific application and quality requirements.

 

Particle size analysis is attached as follows:

 

Guanjie Biotech's Micronized Resveratrol Powder is a high-purity botanical active ingredient produced through advanced micronization technology, designed to improve dispersion, stability, and bioavailability in functional formulations.

● Ultra-fine particle size distribution:
The product demonstrates a tightly controlled micronized range with D10 = 1.134 μm, D50 = 2.124 μm, and D90 = 3.471 μm. The average particle characteristics (D(3,2) = 1.862 μm; D(4,3) = 2.235 μm) indicate uniform granularity and narrow distribution, ensuring consistent processing performance.

● Enhanced functional performance:
The reduced particle size significantly increases specific surface area (3.223 sq m/cc), improving dissolution rate and enhancing absorption efficiency in dietary supplements, beverages, and cosmetic formulations. This allows better bioavailability of resveratrol's antioxidant and anti-aging properties.

● Quality control & application versatility:
Strict production control ensures batch stability and reproducibility. The powder is suitable for capsules, tablets, solid drinks, and skincare products, offering stable performance across multiple industrial applications.

Particle size analysis shows a monomodal distribution with a controlled peak centered around 2–3 μm, confirming excellent milling uniformity and suitability for high-end formulations requiring consistent dispersion behavior. This makes it a reliable ingredient choice for nutraceutical, pharmaceutical, and cosmetic manufacturers seeking improved performance and formulation stability with scalable industrial production support and consistent quality assurance systems.

 

COA

Product Name: Resveratrol( Micronized)
Item	Specification	Result	Method
Basic Product Information
Genus and Species	Pohygonum cuspidatum Sieb et Zucc．	Conform	/
Part of the Plant	Root	Conform	/
Country of Origin	China	Conform	/
Marker Compounds
Assay(Trans-resveratrol)	>99.0%	99.76%	HPLC
Emodin	<0.07%	0.02%	HPLC
Organoleptic Data
Appearance	Fine Powder	Conform	/
Color	Off-white to light yellow	Conform	/
Odor	Characteristic	Conform	/
Taste	Characteristic	Conform	/
Process Data
Method of Processing	Extraction	Conform	/
Solvent(s) Used	Ethanol & Water	Conform	/
Drying Method	Vacuum drying	Conform	/
Excipient	None	Conform	/
Ratio of Extraction	100:1	Conform	/
Physical Characteristics
Solubility	Soluble in Alcohol	Conform	Visual
Particles size analysis	d(10%)	0.353μm	GB/T 5507-2008
d(50%)	1.392μm
d(90%)	2.951μm
Surface area mean diameter D【3,2】	2.423μm
Volume mean diameter D【4,3】	3.757μm
Size range	0.059-112.0 μm
Loss on drying	<1.0%	0.51%	GB/T 14769-1993
Ash Content	<1.0%	0.48%	AOAC 942.05, 18th
Solvent Residue	Eur Pharm (Alcohol)	298ppm	GJ-QCS-1007
Heavy Metals
Total Heavy Metals	<10 ppm	Conform	USP<231>, method II
As	<2.0 ppm	Conform	AOAC 986.15, 18th
Pb	<2.0 ppm	Conform	AOAC 986.15, 18th
Hg	<0.5 ppm	Conform	AOAC 971.21, 18th
Cd	<0.5 ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	<1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

 

What Is Micronized resveratrol powder Used For?

● Anti-aging Activity

Micronized resveratrol powder exhibits enhanced anti-aging potential by effectively mitigating oxidative stress through multiple redox-regulated molecular pathways. Research indicates that chromosomal integrity progressively declines with aging, contributing to cellular dysfunction. Resveratrol has been shown to activate sirtuin proteins, particularly SIRT1, which play a critical role in DNA repair and maintenance of genomic stability. By promoting chromosome protection and regulating cellular aging mechanisms, micronized resveratrol may help delay the onset of age-related deterioration and support overall cellular longevity. Its improved bioavailability further enhances its efficacy in anti-aging applications.

● Anti-inflammatory and Antibacterial Activity

This compound demonstrates significant anti-inflammatory potential by modulating the balance between pro-inflammatory mediators and anti-inflammatory cytokines, as well as regulating chemokine expression to attenuate excessive inflammatory responses. Through these mechanisms, it helps maintain immune homeostasis and prevent tissue damage associated with chronic or acute inflammation. In addition to its anti-inflammatory properties, it exhibits broad-spectrum antimicrobial activity. It has been shown to inhibit the growth of several pathogenic microorganisms, including Staphylococcus aureus, Moraxella catarrhalis, Escherichia coli, and Pseudomonas aeruginosa. Furthermore, it displays notable antiviral activity, particularly against certain enveloped and non-enveloped viruses, such as herpes simplex virus, enteroviruses, and Coxsackie A and B viruses, suggesting potential applications in infection control and supportive therapy.

 

● Immunomodulatory Effects

This ingredient exerts comprehensive immunomodulatory effects by influencing both cellular and humoral immune responses. It can enhance the host's defense mechanisms by reducing pathogen replication and viability while simultaneously regulating immune signaling pathways. Notably, it exhibits a bidirectional regulatory effect on cytokine and chemokine production, helping to balance immune activation and suppression. This dual-action mechanism supports immune system stability and improves the body's ability to respond effectively to external pathogens.

 

 

Product Qualification

Micronized Resveratrol Powder is manufactured in a controlled, clean production environment, with each stage handled by trained and qualified personnel. The entire manufacturing process, as well as the final product specifications, complies with relevant international quality and safety standards. Strict quality control measures are implemented to ensure consistency, purity, and performance. Comprehensive testing is conducted using validated analytical methods. Upon request, we can provide detailed certificates of analysis and supporting test reports to verify product quality and compliance with customer and regulatory requirements.

 

Our factory:

There are two factories both in Baoji city and Shangluo City, Guanjie factories covers an area of 7000㎡, including GMP standard workshop of 2000㎡.

 

Certification:

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

 

Package&Warehouse:

 

Shipment:

DHL, FEDEX, Sea freight,Air freight you can choose.

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