Luteolin powder is a natural flavonoid whose structure is shown in Fig. 1. It is named after Reseda odorata Linn. which was originally isolated from the family Lignanaceae. From the structure, it is known that lignan is a polyphenolic hydroxyl compound with poor lipophilicity, high lattice energy due to intermolecular forces between hydroxyl groups, and its poor hydrophilicity. Its special structure leads to low solubility in a variety of solvents, which poses certain challenges for its preparation and application.
Structure Of Luteolin
Luteolin powder has rich pharmacological effects and strong medicinal value, and are of great significance to human health because of their precise efficacy against major diseases. Lignans are not only anti-inflammatory, anti-oxidant, reduce the damage caused by inflammatory factors and excessive reactive oxygen species, protect normal tissues and cells; protect the nervous system, reduce the occurrence of neuropathy, improve memory and cognitive function. It also can achieve anti-tumor effects by inhibiting tumor cell proliferation and promoting apoptosis. Lignans are widely available in a variety of plants, especially in fruits and vegetables.
The current semi-synthetic and full synthetic processes of lignans are complicated and costly; extraction from natural plants is the best way to obtain lignans. The research of innovative and effective extraction process has become the goal of many researchers. In recent years, domestic and foreign scholars have conducted a lot of research on the extraction and purification process of lignocaine.
The extraction process about Luteolin powder can be divided into 2 main categories, traditional extraction process and new extraction technology, among which the new process can be divided into direct extraction and extraction after raw material pretreatment, the former has ultrasonic assisted method, microwave assisted method, supercritical fluid extraction method, ionic liquid synergistic extraction method; the latter has enzyme assisted method and steam blast pretreatment method, in order to obtain high yield and stable quality of lignocerin.
Today we look at the solvent extraction method first. Solvent extraction method is a more traditional extraction method, divided into maceration method, percolation method, water decoction method, reflux extraction method and continuous extraction method, the principle is to select the solvent with high solubility of the active ingredients of the raw material for extraction. The current extraction method commonly applied to lignocaine is reflux extraction method, and the solvent is mostly 60%-80% methanol or ethanol. In the related reports about solvent extraction method, some scholars have used medicinal plants such as Huangzhu, Uvaceae, Du Hong Hua, Bai Mao Xia Gu Cao, and Dou Yi Wei to extract lignocaine, and the extraction rate was in the range of 1% to 3%. Yang Jian et al. selected peanut shells to investigate the best process of ethanol reflux leaching of lignocaine, and the application of the best extraction conditions resulted in a lignocaine content of 0.013 mg/g. Compared with the new process technology, the extraction by solvent method alone is not sufficient for the utilization of the herb and cannot achieve the best results yet.
Guan jie focuses on luteolin powder researching, producing and sale. Our source is main from bud and peanut shells. We have our own two factories. They cover an area of 7000㎡, including GMP standard workshop of 2000㎡. All of which are fully compliant with good manufacturing policies and follow the strictest quality controls. We can provide you with high quality products at the best price. If you interested in our products, please feel free to contact us:info@gybiotech.com
