Hesperidin Powder

Hesperidin Powder Supplier：

Guanjie Biotech is a reliable Hesperidin Powder supplier, providing high-quality citrus flavonoid ingredients for the nutraceutical, food, and pharmaceutical industries. Hesperidin is a naturally occurring compound extracted from citrus peels and is widely used for its antioxidant and vascular health support properties. Guanjie Biotech offers Hesperidin Powder with CAS No. 520-26-3, available in specifications of 90%, 92%, 95%, and 98% purity to meet various formulation needs. Product quality is strictly controlled and verified by HPLC testing, ensuring accuracy, purity, and batch consistency. The product appears as a light-yellow fine powder, making it easy to handle and suitable for capsules, tablets, functional foods, and beverage applications. Please feel free to contact us at info@gybiotech.com.

 

What Is Hesperidin Source?

Hesperidin is synthesized from hesperidin and rutose by removing a molecule of water through complex biological reactions

C16H14O6+C12H22O10→C28H34O15+H2O

 

COA

Item	Specification	Result	Method
Basic Product Information
Genus and Species	Citrus aurantium L.	Conform	/
Part of the Plant	Fruit	Conform	/
Country of Origin	China	Conform	/
Marker Compounds
Hesperidine	>90.0%	90.26%	HPLC
Organoleptic Data
Appearance	Powder	Conform	GJ-QCS-1008
Color	Light-Yellow fine powder	Conform	GB/T 5492-2008
Odor	Characteristic	Conform	GB/T 5492-2008
Taste	Characteristic	Conform	GB/T 5492-2008
Process Data
Method of Processing	Extraction	Conform	/
Solvent(s) Used	Ethanol & Water	Conform	/
Drying Method	Vacuum drying	Conform	/
Excipient	None	Conform	/
Physical Characteristics
Melting point	258-262 ℃	259.5-260℃	GB21781-2008T
Particles size analysis	d(10%)	0.454μm
d(50%)	3.021μm
d(90%)	4.985μm	GB/T 5507-2008
( Micronized)	Surface area mean diameter D【3,2】	3.116μm
	Volume mean diameter D【4,3】	4.801μm
	Size range	0.0251-195.0 μm
Moisture	<5.0%	1.8%	GB/T 14769-1993
Ash Content	<1.0%	0.3%	AOAC 942.05, 18th
Solvent Residue	None	Conform	GJ-QCS-1007
Heavy Metals
Total Heavy Metals	<10 ppm	Conform	USP<231>, method II
Arsenic	<2.0 ppm	Conform	AOAC 986.15, 18th
Lead	<2.0 ppm	Conform	AOAC 986.15, 18th
Mercury	<0.5 ppm	Conform	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	<1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	<100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

How is Hesperidin Produced?

Most of hesperidin is found in the waste of citrus processing. If the peel and fruit capsule, the content of hesperidin in the ripe peel and tissue is the highest (30%-50% in the endocarp, tangerine, pit, and pulp). 30%-50% in the middle, 10%-20% in the exocarp), and a lower content of 1%-5% in the juice and orange sac. 

 

The extraction methods of hesperidin include solvent extraction method, alkali extraction and acid precipitation method, carbon powder adsorption method and ion exchange method, among which the alkali extraction and acid precipitation method is simple in operation, low in cost and high in extraction rate. Hesperidin is soluble in dilute alkali and pyridine and hot water above 70℃, slightly soluble in methanol, almost insoluble in acetone, benzene and chloroform.

 

The extraction of hesperidin mainly utilizes the two phenolic hydroxyl groups contained in it to react with sodium ions in the solution under alkaline conditions to form sodium salt and dissolve out, and then acidify and cool to make it precipitate out of the solution. The extraction of hesperidin from citrus peel generally adopts thermal extraction method and soaking extraction method, and the yield is not ideal.

 

In recent years, ultrasonic extraction of active ingredients from natural Chemicalbook plants (especially Chinese herbal medicines) has been widely carried out, and certain progress has been made. Use hesperidin to open-loop dissolution under alkaline conditions for extraction and closed-loop precipitation for separation under acidic conditions. Increasing the amount of alkali during extraction can reduce the amount of ethanol, but the alkalinity should not be too large, otherwise, hesperidin will be easily oxidized destroy.

What Is Hesperidin Used For?

1. Hesperidin has the functions of maintaining osmotic pressure, enhancing capillary toughness, shortening bleeding time, and lowering cholesterol. It is one of the main raw materials of the patent medicine "Maitong".

1.  

2. It can be used as a natural antioxidant and chemical agent in the food industry.

 

3. Can also be used in the cosmetic industry. Relevant studies have shown that hesperidin has a broad-spectrum antibacterial effect on common food contaminating bacteria, and has a significant inhibitory effect on Bacillus subtilis, Salmonella typhimurium, Shigella flexneri, Streptococcus hemolyticus and Vibrio cholerae. , So it is widely used in food additives and food processing.

 

What Does Hesperidin Do?

1. Hesperidin powder can reduce inflammation;

It can improve the blood cell aggregation and capillary resistance in the conjunctiva of the eye caused by lack of vitamin C in guinea pigs (enhancing the effect of vitamin C); but it has also been reported that it can reduce blood cell aggregation in horses. It can prolong the survival time of rats by co-feeding it with Thrombogenic diet or with atherogenic diet. Stimulates the growth rate of vitamin C-deficient guinea pigs. Can enhance the content of ascorbic acid (vitamin C) in guinea pig adrenal gland, spleen and white blood cells.

2.It can reduce Oxidative Damagel;

3.Hesperidin powder can lower Blood Pressurel;

4.This product can be Anti-Diabetesl;

5.It can help to control weight.

6.Antiviral

Before adding vesicular stomatitis virus, the mouse fibroblasts were pre-incubated in 200μg/ml of this product. After such treatment, the cells can be protected from the virus for about 24 hours. Pre-treatment of HeLa cells with this product can prevent influenza virus infection. The antiviral activity of this product can be eliminated by hyaluronidase.

7.Other

It has the effect of preventing frostbite and inhibiting the aldehyde reductase of rat eye lens.

 

Why Choose Us?

We are one of the leading plant extract suppliers integrating R&D, production and sales.

We always adheres to the Enterprise faith of "quality first, customer first", and sincerely cooperate with you.

Our factory can stock the main products all the year round to prevent any delay.

Professional shipping agents ensure that the goods can be exported safely and quickly.

 

Our factory:

There are two factories both in Baoji city and Shangluo City, Guanjie factories covers an area of 7000㎡, including GMP standard workshop of 2000㎡. Pure NMN Powder is produced in a clean working environment and every step of the process is conducted by highly qualified professionals. Both processes of manufacture and the product itself meet all international standards. 

 

Product Qualification

Hesperidin Bulk Powder is produced in a clean working environment and every step of the process is conducted by highly qualified professionals. 

 

Testing Center: 

Both the production processes of manufacture and the product itself meet all international standards. And if you need our testing report, we can provide you.

 

Certification

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

 

Package&Storage 

(1)Package:

● 5-10Kg/bag: If you need 5-10kg,we put it in carton. 

● 1Kg/Bag:If you need 25kg or more,we put aluminum foil bag in our drum. 

(2)Storage:

Kept away from strong light and heat.

 

 

Shipment

Door to door service easy to pick up the goods and by sea,air.

 

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