Spermidine Wheat Germ Extract

Guanjie Biotech is a spermidine wheat germ extract supplier. Wheat germ is the best source of spermidine. Our product is a white powder with a 1% assay. Spermidine is a naturally occurring polyamine found in living organisms. It is an organic compound with multiple amine groups. You can choose from different sizes. You are welcome to enquire with us at info@gybiotech.com.

 

Product	CAS No.	Grade	Packing specification
spermidine	124-20-9	Food Grade	1kg 25kg

 

Test Items	Specification	Result	MOA
Appearance	White to off-white powder	Off-White Powder	Visual
Purity	≥98%	99.0%	GC
Solubility	Soluble in water	Conform	CP2020
Loss on drying	≤1.0%	0.28%	CP2020
Residue on ignition	0.2%	0.02%	CP2020
Ethanol(GC)	5000ppm	600ppm	GC
Heavy Metal Content
Pb	≤0.1 ppm	Conform	GB5009
Hg	≤0.1ppm	Conform	GB5009
Cd	≤0.2 ppm	Conform	GB5009
As	≤0.1ppm	Conform	GB5009
Total microbial count	≤500CFU/g	<10	GB4789
Coliform	≤0.92MPN/g	Conform	GB4789
Mold and yeast	≤50CFU/g	Conform	GB4789
Staphylococcus aureus	0/25g	Conform	GB4789
Salmonella	0/25g	Conform	GB4789
Conclusion	All inspection items conform with the specifications.
Storage Condition	Sealed packaging, stored at cool, dry and away from light.

 

 

Spermidine Wheat Germ Extract is mainly from wheat germ. Spermidine is widely distributed in living organisms. This includes organisms such as bacteria, mammals, birds, insects, and plants. It is found in several organs. Such as, the human kidneys, liver, intestines, and stomach. Spermidine-rich foods mainly include broccoli, cauliflower, mushrooms, soya beans, green peppers, peas and hazelnuts.

 

Spermidine is a powerful natural polyamine renowned for its cellular renewal and anti-aging benefits. As consumer interest in longevity grows, incorporating high-quality spermidine powder into daily health routines has become a popular strategy for promoting autophagy and healthy aging.

Here is how key body processes and natural sources contribute to maintaining optimal levels:

Spermine/Spermidine Metabolism: In mammalian cells, spermine is produced from its precursor, putrescine, or through the oxidative degradation of spermine. Maintaining balanced metabolism is essential for cellular health.

Gut Microbiota: The gut microbiota is an important source of polyamine synthesis. In mice, the concentration of polyamines in the intestinal lumen depends directly on colonic microbiota. Oral administration of the polyamine-producing probiotic Bifidobacterium bifidum LKM512 upregulates blood levels of polyamines, suppressing inflammatory responses and prolonging lifespan in aged mice.

Supplements: Because spermidine wheat germ extract has anti-aging properties, many bulk spermidine powder and dietary supplements have appeared on the market. Wheat germ serves as the premier source for natural spermidine powder extraction. Guanjie Biotech is a leading spermidine-rich wheat germ extract producer and manufacturer. Welcome to consult us for wholesale opportunities; we hold comprehensive production and quality certificates.

Food Sources: Dietary spermidine ingested from food is rapidly absorbed in the intestines and distributed throughout the body. Consuming foods high in polyamines, or fortifying your diet with pure wheat germ spermidine powder, effectively increases overall polyamine concentrations in the body.

 

Spermidine plays a vital role in cellular health, longevity, and overall wellness. Incorporating high-purity spermidine powder into your daily routine offers several key health benefits:

● Slowing Down Aging:

Spermidine promotes autophagy-an essential internal cellular cleansing process that removes damaged organelles and misfolded proteins, directly slowing cellular aging.

● Antioxidant & Cardiovascular Protection:

With strong antioxidant activity, spermidine powder for autophagy neutralizes free radicals to minimize oxidative stress. In cardiovascular health, it reduces plaque accumulation, lowers cardiac hypertrophy, and improves blood pressure. Consuming a natural spermidine wheat germ extract supports long-term cardiac resilience and reduces mortality risks.

● Energy Metabolism & Neuroprotection:

Spermidine regulates energy production by improving glucose utilization and mitochondrial efficiency. Furthermore, it supports neuroglial cell regulation, synaptic transmission, and neuronal development to combat neuropathy.

● Growth, Immunity & Reproductive Health:

By stimulating growth hormone secretion, spermidine aids tissue development while bolstering immune defenses through white blood cell production. Additionally, because natural polyamine levels decline over time, sourcing the best spermidine supplements helps restore declining levels, improving ovarian function and extending female reproductive health.

Adding anti-aging spermidine powder to your health regimen provides systemic protection, optimizing cellular vitality from head to toe.

 

Medicine Field

● Cardiovascular & Metabolic Health:

Preclinical studies demonstrate that spermidine significantly enhances the angiogenic capacity of senescent endothelial cells, promoting neovascularization in senescent mice under ischemic conditions. This demonstrates clear therapeutic value for ischemic cardiovascular disease. Additionally, high-grade spermidine powder improves cardiac function and reduces myocardial damage in diabetic models by decreasing reactive oxygen species (ROS), endoplasmic reticulum stress (ERS), and Pannexin-1-mediated iron deposition-effectively alleviating diabetic cardiomyopathy. For metabolic health, spermidine effectively alleviates obesity and metabolic disorders by activating brown fat and skeletal muscle, improving insulin resistance, and reducing hepatic steatosis.

● Cellular Longevity & Anti-Aging Mechanisms:

As a natural polyamine, an anti-aging spermidine supplement possesses protective properties that extend biological lifespan while exhibiting potential anti-tumor effects by enhancing mitochondrial function and promoting autophagy. Utilizing natural spermidine wheat germ extract helps maintain telomere length, slow cellular aging, and reduce age-related diseases across various model systems.

● Neuroprotection & Immune Response:

In neurological health, pure spermidine bulk powder exhibits the potential to dissolve beta-amyloid plaques-a major biomarker strongly correlated with age-related memory decline and neurocognitive changes like dementia. Furthermore, spermidine promotes hepatitis B virus clearance by increasing IL-21 and IFN-gamma expression. In LPS-stimulated BV2 microglia, it demonstrates potent anti-inflammatory effects by inhibiting NO, PGE2, IL-6, and TNF-α via NF-κB, PI3K/Akt, and MAPK signaling pathways.

● Organ Protection & Antioxidant Capacity:

Spermidine works by inhibiting DNA nitration and PARP1 activation; wheat germ oil spermidine effectively protects kidneys from ischemia-reperfusion injury, offering a strategy for acute kidney injury. Spermidine powder also significantly reduces lung inflammation, neutrophil counts, collagen accumulation, and lung tissue damage to prevent acute lung injury and pulmonary fibrosis. Finally, its powerful antioxidant activity scavenges DPPH and hydroxyl radicals, preventing DNA oxidation and elevating protective antioxidant enzymes.

 

Food Field

Spermidine powder is rapidly becoming a high-demand ingredient in functional foods and anti-aging cell nutrition. Rich in natural polyamines, spermidine wheat germ extract works at the cellular level by inducing autophagy, making it a cornerstone for metabolic health, longevity formulations, and immune system support.

● Metabolic & Liver Support:

Spermidine powder shows exceptional potential for preventing non-alcoholic fatty liver disease, managing obesity, and alleviating type II diabetes symptoms, offering significant benefits for functional food formulations.

● Gut Health Enhancement:

Incorporating natural spermidine extract into foods boosts Lachnospiraceae bacterial abundance and strengthens intestinal barrier function, improving overall gut microbiome health.

● Thermogenesis & Weight Management:

Standardized spermidine wheat germ extract activates brown adipose tissue and skeletal muscle, aiding in weight management and metabolic disorder prevention.

● Longevity & Telomere Protection:

Dietary supplementation with spermidine-rich foods helps preserve telomere length and trigger cellular autophagy, driving innovation in anti-aging life-extension products.

● Immune System Boosting:

By enhancing Nb CAR-T cytotoxicity, proliferation, and cellular memory in lymphoma models, spermidine supplement benefits extend to advanced immune-supportive food applications.

● Cognitive & Brain Function:

Long-term clinical administration of wheat germ extract powder demonstrates positive effects on memory performance in Alzheimer's patients, highlighting its vast value for neuroprotective functional nutrition.

 

Agriculture Field

Spermidine powder is a powerful polyamine compound gaining traction in modern farming. Key Spermidine powder keywords like plant growth regulator, biostimulant, wheat germ extract Spermidine, and crop protection naturally integrate into agricultural applications.

In the agriculture field, Spermidine powder functions as a high-performance biostimulant. Research shows Spermidine is used to preserve citrus, where it significantly reduces fruit drop while maintaining fruit quality and flavor. Applying Spermidine powder at a concentration as low as 1 mmol/L effectively enhances plant immunity and environmental stress tolerance.

Furthermore, Spermidine powder wheat germ extract demonstrated the potential to reduce oxidative stress in the silk glands of domestic silkworms. This provides a beneficial antioxidant crop protection solution for sericulture farmers, making it an invaluable natural addition to silkworm rearing and sustainable yield management.

 

Our factory:

There are two factories, both in Baoji City and Shangluo City. Guanjie factories cover an area of 7000㎡, including the GMP standard workshop of 2000㎡.

 

Product Qualification

Spermidine wheat germ extract is produced in a clean working environment and every step is conducted by highly qualified professionals. Both the production processes of manufacture and the resveratrol 98 powder itself meet all international standards. And if you need our testing report, we can provide you.

 

Testing Center:

Both the production processes of manufacture and the Spermidine Wheat Germ Extract itself meet all international standards. And if you need our testing report, we can provide it.

 

Certification

We have obtained the NON-GMO certification from Pony Test International Group. We have obtained certifications in HALAL, ISO 9001, ISO 22000, Kosher, PAHS, SC, and so on.

 

 

Package&Warehouse:

 

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