Bulk Rutin

Bulk Rutin Supplier:

Guanjie Biotech is a bulk rutin powder supplier. It is a yellow or greenish-yellow, crystalline powder with an assay of 95%. It is practically insoluble in chloroform and ether. And it dissolves in a solution of alkali hydroxides. We have independent labs and factories. Our product is high quality and low price. If you are interested in our product, please inquiry us: info@gybiotech.com.

 

Why Choose Guanjie Biotech?

Guanjie Biotech is your trusted partner for high-quality Sophora Japonica Extract. We focus on quality, certification, and innovation to give you the best.

● Quality You Can Trust
Every Bulk Rutin order comes with a guarantee-it will always match its Certificate of Analysis (CoA). If not, we promise a 100% exchange, return, or refund with no questions asked. You'll always get the pure and consistent product you expect.

● Certified for Global Standards
Our products and facilities are certified with ISO 9001, HACCP, SC, KOSHER, and HALAL. This means our extracts meet strict international standards for quality, safety, and suitability across different markets.

● Innovation from Experts
We have our own R&D center with a team of 10 professional scientists. They focus on improving bulk rutin extraction methods, maintaining strict quality control, and solving customized solutions to support your product needs. Choose Guanjie Biotech for reliable products.

 

 

COA

Analysis	Specification	Results
Assay (anhydrous substance) by UV	> 95%	95.5%
Physical & Chemical Control
Identification	Positive	Complies
Appearance	Yellow or greenish-yellow, crystalline powder	Complies
Odor	Characteristic	Complies
Taste	Characteristic	Complies
Particle size	100% pass 80 mesh	Complies
Impurity( Quercetin)	<4.0%	1.13%
Red pigments	<0.004%	Complies
Loss on drying	5.5-9.0%	8.02%
Solubility	Practically insoluble in chloroform and ether; Infinitesimally soluble in cool water; Sparingly soluble in boiling ethanol and boiling water; Dissolves in solution of alkali hydroxides	Complies
Residual Solvents	Eur.Pharm.	Complies
Sulfated Ash	<1%	0.11%
Heavy Metals	<10PPM	0.40PPM
Pb	<2.0ppm	Complies
As	<2.0ppm	Complies
Hg	<0.2ppm	Complies
Cd	<0.2ppm	Complies
Pesticides	Negative	Negative
Microbiological
Total Plate Count	<1000CFU/gm	Complies
Yeast&Mold	<100CFU/gm	Complies
Salmonella	Negative	Negative
E.Coli.	Negative	Negative
Conclusion	The test results conform to NF11

 

​Brief Introduction

Bulk Rutin Powder is a kind of plant pigment, which is found in some fruits and vegetables. This product can increase the thickness of blood vessels to prevent varicose veins, internal bleeding, hemorrhoids, and stroke caused by vein or artery rupture. The powder is also used to prevent side effects from cancer treatment. The powder also has a certain effect on the treatment of osteoarthritis. In addition, the product is also a good antioxidant, widely used in cosmetics. Rutin bulk powder is also used in the field of medicine, usually made into tablets, capsules, and granules to enhance human immunity.

 

Function:

● Cardiovascular health:
Rutin bulk powder may help reduce inflammation and protect against oxidative stress, both of which are factors that can contribute to cardiovascular disease.

● Anti-inflammatory effects:
Bulk Rutin powder has been shown to have anti-inflammatory properties, which may make it useful for conditions such as arthritis, allergies, and asthma.

● Antioxidant benefits:
Rutin has strong antioxidant properties, which may help protect against damage caused by free radicals.

● Skin health:
Bulk Rutin may help improve the appearance of skin by protecting against damage from UV rays and supporting collagen production.

 

Mechanism Of Action

● Rutin has good antioxidant capacity and intervenes in cellular and intracellular oxidative damage.
Rutin can protect tert-butyl hydroperoxide-induced oxidative damage in hepatocytes by regulating phosphatidylinositol kinase/protein kinase B and nuclear factor-κB signaling pathways. Bulk Rutin also attenuates mitochondrial dysfunction caused by increased levels of reactive oxygen species (ROS) by reducing total cellular reactive oxygen species levels, eliminating hydroxyl radicals, and scavenging superoxide anion. It can be used in the treatment of degenerative diseases associated with aging.

 

● Rutin has cardioprotective effects
It can improve the myocardial injury induced by antitumor drugs such as cisplatin, lipopolysaccharide, piroxicam, carfilzomib and so on. At the same time, Rutin Bulk also has an inhibitory effect on apoptosis induced by ischemia/reperfusion injury, and the mechanism of its cardioprotective effect includes regulating the levels of cytokines and oxidative kinases, and regulating the signaling pathway to regulate the expression of related genes.

 

● Bulk rutin can reduce the level of inflammatory factors by decreasing the level of inflammatory factors.
Studies have confirmed that rutin can inhibit the aggregation of neutrophils in yeast polysaccharide-induced arthritis mice and inhibit the synthesis of tumor necrosis factor-α (TNF-α) in joints to reduce joint inflammation.

 

● Apoptosis is a type of programmed cell death.
Rutin inhibits vancomycin-induced apoptosis by modulating oxidative kinase activity and ROS content to reduce nephrotoxicity. It also protects neurons by attenuating sodium nitroprusside-induced PC12 neuronal cell injury through the activation of extracellular regulatory protein kinase and reducing apoptosis triggered by NO production by nitric oxide synthase. In addition, rutin reduced intracellular NO and O2- levels and Bax/Bcl-2 ratio and increased phosphorylated Akt/Akt ratio. This restores superoxide dismutase activity and inhibits Aeromonas hydrophila-induced apoptosis to reduce muscle inflammation.

 

● The antiviral activity of rutin is usually exerted after cells are infected with the virus, acting at the level of replication or later in the life cycle.
Bulk Rutin significantly inhibited the enzymatic activity of recombinant 3C protease protein and viral 3C protease in enterovirus A71 (enterovirus-A71, EV-A71) infected cells. This inhibited the replication of enterovirus A71 to reduce the incidence of encephalitis and pulmonary edema. In addition, rutin inhibits influenza virus neuraminidase activity, and shows excellent in vitro inhibitory effects against influenza virus strains A/PuertoRico/8/1934 (H1N1), A/FM1/1/47 (H1N1), A/Beijing/32/92 (H3N2), and A/Human/Hubei/3/2005 (H3N2). (H3N2), A/Human/Hubei/3/2005 (H3N2) strains showed excellent in vitro inhibition.

 

● Rutin was proven to have antibacterial activity.
However, its direct antibacterial effect is weaker than that of antibacterial drugs. If the two together can play a synergistic effect, rutin powder and amphotericin B, mulberry pigment, etc. The antibacterial effect is additive and can reduce bacterial resistance. Therefore, the development of Sophora Japonica Extract and antibiotics can be combined with antibacterial drugs to achieve efficiency and reduce toxicity.

 

● Rutin has a regulatory effect on glucose and lipid metabolism.
Bulk Rutin has a therapeutic effect on diabetic complications. Rutin reduces serum cardiac myosin content in mice with diabetic cardiomyopathy and reduces fibrosis to mitigate myocardial injury. In addition, rutin can improve renal function and inhibit renal tissue lesions in diabetic rats through antioxidant and free radical scavenging effects.

 

Factory&Team：

 

Certification

 

Package & Shipment

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