Sesamin Powder

Brief Introduction

Guanjie Biotech has focused on Sesamin Powder research, production, and sale. We have been in this field for 20 years. Sesamin bulk powder is a white powder, soluble in methanol, ethanol, and other organic solvents, and widely used in pharmaceuticals. We guarantee the quality is in conformity with the Certificate of Analysis provided by us, if not, we accept 100% exchange, return and refund. Our company has an independent research and development center. We can provide you with high-quality products at the best price, as a professional natural ferulic acid supplier. Sesamin bulk Powder also has antibacterial, antiviral, anti-inflammatory, and antioxidant properties, mainly used to regulate blood lipids and blood pressure and improve liver health. Sesame extract can increase the rate of oxidation of fatty acids in the granulosa and peroxisomes. so sesamin is arguably one of the most effective liver-protecting ingredients in health food.

 

 

 

COA

Item	Specification	Result	Method
Basic Product Information
Genus and Species	Sesamum indicum L.	Conform	/
Part of the Plant	Seeds	Conform	/
Country of Origin	China	Conform	/
Marker Compounds
Sesamin	≥ 98.0%	98.19%	HPLC
Organoleptic Data
Appearance	Powder	Conform	Visual
Color	White crystalline powder	Conform	Visual
Odor	Characteristic	Conform	Organoleptic
Identification	Positive	Conform	TLC
Process Data
Method of Processing	Extraction	Conform	/
Solvent(s) Used	Ethanol & Water	Conform	/
Drying Method	Vacuum drying	Conform	/
Excipient	None	Conform	/
Physical Characteristics
Particle Size	>95.0% pass 30mesh	Conform	USP #30 Sieve
Loss on Drying	≤ 0.5%	0.38%	USP39-NF34<731>
Residue on Ignition	≤ 0.5%	0.05%	USP39-NF34<281>
Residual Ethanol	≤ 5,000 μg/g	6.1x102 μg/g	USP39-NF34<467>
Pesticide Residues	USP<561>	Conform	USP39-NF34<561>
Heavy Metals
Total Heavy Metals	≤ 10 μg/g	Conform	USP39-NF34<231>
Arsenic (As)	≤ 1.0 μg/g	ND (< 0.1 μg/g)	ICP-MS
Cadmium (Cd)	≤ 0.5 μg/g	ND (< 0.01 μg/g)	ICP-MS
Lead (Pb)	≤ 1.0 μg/g	ND (< 0.1 μg/g)	ICP-MS
Mercury (Hg)	≤ 0.5 μg/g	ND (< 0.01 μg/g)	ICP-MS
Microbiology
Total Plate Count	≤ 1,000 cfu/g	<10 cfu/g	USP39-NF34<2021>
Molds and Yeasts	≤ 100 cfu/g	<10 cfu/g	USP39-NF34<2021>
Salmonella	Absence	Conform	USP39-NF34<2022>
E. Coli	Absence	Conform	USP39-NF34<2022>
Staphylococcus aureus	Absence	Conform	USP39-NF34<2022>
Aflatoxins	≤ 20 ppb	ND	USP39-NF34<561>

 

Process:

 

 

Production Process：

Sesamin is a natural plant compound that is mainly derived from sesame seeds. Guanjie Biotech uses two extraction methods: water extraction and ethanol extraction. These methods are used to extract sesamin powder from sesame seeds, and after proper processing, a high-purity sesamin bulk powder is obtained. The following is a detailed production process of these two extraction methods.

 

1. Water extraction

Water extraction is a traditional method of extracting sesamin from sesame seeds using water as a solvent. We use the solubility of water and the solubility of sesamin in water to extract sesamin from sesame seeds. Water extraction is relatively simple and easy to operate. This does not require the use of toxic solvents.

 

•Raw material preparation

First, select high-quality sesame seeds. Sesame seeds should be free of mold, pollution, and impurities to ensure their quality. Sesame seeds need to be cleaned before extraction to remove external impurities such as dust and weeds.

 

•Pretreatment of sesame seeds

Sesame seeds usually need to be pretreated before water extraction. The sesame seeds are crushed by mechanical equipment to increase the surface area of ​​the sesame seeds, which is conducive to subsequent extraction. Removing the outer shell of sesame can improve the extraction efficiency and the concentration of sesamin.

 

•Water extraction

Put the treated sesame seeds in a suitable container and add an appropriate amount of water. The amount of water is adjusted according to the amount of sesame seeds and the extraction effect. Hot water extraction is usually used to promote the dissolution of sesamin by heating water. At this time, the temperature is generally controlled between 80-90℃ and the time is controlled between 30 minutes and 1 hour.

During the heating process, sesamin in sesame seeds is released into water through the dissolution of water. At this time, continuous stirring is required to improve the dissolution efficiency and uniformity.

 

•Solid-liquid separation

After the extraction is completed, the obtained liquid contains sesamin components. At this time, solid-liquid separation is required to remove the residual solid impurities.

 

•Concentration

The separated liquid contains sesamin and other soluble components. In order to increase the concentration of sesamin, concentration is usually required. Concentration can be achieved by evaporating water. Common concentration methods include vacuum evaporation and normal pressure evaporation.

 

•Drying

After the water is removed, the concentrated liquid is still a water-containing slurry. To get sesamin powder, Guanjie Biotech uses vacuum drying to remove water. The vacuum drying method can remove moisture at a lower temperature and effectively protect the activity of sesamin. At the same time, it can reduce thermal degradation and improve the stability of the product.

 

•Finished product screening and packaging

Finally, the sesamin dried powder needs to be screened to remove impurities with larger particles and ensure that the particle size of the product is consistent. The screened sesamin wholesale powder is packaged in a sealed container to avoid the influence of moisture and light, thereby extending the shelf life.

 

2.Ethanol extraction method

Ethanol extraction method is an extraction method that uses ethanol as a solvent to dissolve sesamin in sesame seeds. Ethanol extraction method has the advantages of high extraction efficiency and short extraction time. Therefore, it is widely used in the production of some high-purity sesamin products.

•Raw material preparation

Like the water extraction method, high-quality sesame seeds need to be selected first. Sesame seeds should be cleaned to remove impurities and contaminants to ensure the purity of the extracted raw materials.

 

•Pretreatment of sesame seeds

Sesame seeds also need to be pretreated before ethanol extraction. Usually, crushing and shelling are used to increase the contact area of ​​sesame seeds to improve the extraction effect of ethanol.

 

•Solvent configuration

The key to the ethanol extraction method is to use ethanol as a solvent. The concentration of ethanol is usually between 60% and 80%. Higher concentrations of ethanol help to increase the solubility of sesamin. The configuration of the solvent needs to be determined according to the solubility characteristics of sesamin. Too low a concentration may result in incomplete extraction, and too high a concentration may result in the dissolution of other components.

 

•Extraction process

The treated sesame seeds are mixed with ethanol for extraction. The extraction process can be performed by soaking, reflux extraction, or ultrasonic-assisted extraction. The extraction time is generally 1-2 hours. The specific time needs to be adjusted according to the dissolution characteristics of sesamin.

 

•Solid-liquid separation

After the extraction is completed, the solid residue of the sesame seeds is removed by an appropriate solid-liquid separation method. The residue is usually separated by filtration or centrifugation to obtain an ethanol solution containing sesamin.

 

•Solvent evaporation

The ethanol solution still contains a large amount of ethanol, so solvent evaporation is required to remove the ethanol. Guanjie Biotech uses vacuum evaporation to remove the ethanol solvent under low temperature conditions to reduce the degradation of sesamin and improve the purity of the product.

 

•Drying and powder preparation

After the solvent evaporates, the sesamin concentrate needs to be further dried. Guanjie Biotech uses vacuum drying to dry the sesamin to maintain the stability and activity of sesamin.

 

•Finished product screening and packaging

Finally, the dried sesamin powder needs to be screened to ensure uniform particle size. The screened sesamin is packaged in sealed containers to avoid moisture and light.

 

The extraction methods of sesamin mainly include water extraction and ethanol extraction, each of which has its own advantages and disadvantages. In actual production, Guanjie Biotech uses vacuum drying and vacuum evaporation to improve the purity and stability of sesamin and ensure product quality. Regardless of which method is used, ensuring the quality of the raw materials and the standardization of the extraction process are the key to obtaining high-quality sesamin powder.

 

 

Function:

● Reduction of liver injury

It was found that feeding 100mg/kg/day of sesquiterpene improved the liver damage caused by CCl4.

 

● Reduction of alcoholic liver injury

It was found that the administration of 0.1% sesamin powder in the diet could improve the index of ALT and AST caused by alcohol and other abnormalities of fat metabolism caused by alcohol.

 

● Improvement of liver index and fatty liver

In a human experiment using a Taiwanese product containing a combination of sesamin, schisandra and VitE, it was found that daily consumption of sesamin 10-12mg/day, schisandra 0.24-0.5mg/day and Vit E 10mg for five months reduced the liver indices of ALT and AST, in addition to an increase in antioxidant-related indices and an improvement in fatty liver.

 

Ingredients

● Sesquiterpene 11.06mg+Pentosidine B 20mg

According to the results of animal tests, it helped to reduce the GOT and GPT values in serum against carbon tetrachloride-induced liver damage in rats .

 

● Sesquiterpene 8-12mg+Vitamin E 44-66mg

The results of animal tests showed that the ingestion of this product helps to delay the carbon tetrachloride-induced chemical liver injury. Sesamin(Sesamin):It can protect the liver, detoxify, anti-fatigue and help sleep.

 

● Sesamolin: 

Digested by the body into sesamin powder, can help purify the blood, tissue cell regeneration and repair, inhibit tumors, inhibit chronic diseases, and anti-aging.

 

Factory&Team：

 

Certification

 

Package & Shipment

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