Bulk ergothioneine powder has gone from a supporting role to becoming a popular product sought after by various brands. As a 'new generation of immortality drug' of ergothioneine, it ultimately has superiority and charm. The next step is to reveal them all.
Ergothioneine is an important element of health and vitality
In 1909, Charles Tanret was researching the ergot fungus that destroys rye grain. He isolated a unique crystalline sulfur compound. This water-soluble thiol was named ergothioneine after the ergot fungus.
In subsequent studies, ergothioneine was found to be a rare natural amino acid homologous to the human body. It accumulates in high concentrations in a variety of cells and tissues. It is most abundant in red blood cells, bone marrow, liver, kidneys, and the lens and cornea of the eye.
Studies have shown that people who take ergothioneine are less likely to get sick and age relatively slowly. And it can alter the lifespan of the body's senescent cells, extending overall life expectancy by one-third.

Bruce Ames, a member of the American Academy of Sciences, an expert on cancer and anti-aging, and a professor in the Department of Biochemistry and Molecular Biology at the University of California, calls ergothioneine the 'longevity vitamin.'
Dr B.D. Paul of the Hopkins University School of Medicine found that ergothioneine is the only long-lasting natural antioxidant that enters the mitochondria and nucleus of cells. It is transported to the mitochondria, the main 'foci' of free radical production in the cell, by the 'OCTN-1 transporter protein'. It protects the mitochondria from oxidative damage while directly scavenging reactive oxygen radicals. It removes aging factors from the root of the problem. Therefore, ergothioneine is more easily absorbed by the body and its antioxidant effect is longer lasting.
Taking bulk ergothioneine powder can age slower and more vigourously than a naturally grown living body of the same age. The conclusion that living organisms can grow back was accepted by the biological community and shocked the world.
However, due to the ergothioneine human body can not be synthesised, and the cost of extraction is very expensive. Once as high as 1 million U.S. dollars / kg, the high price makes many people are screeching.
So for a long time, people could only get ergothioneine from matsutake mushrooms, ganoderma lucidum, porcini mushrooms, monkey head mushrooms, and meats such as beef, pork, lamb and chicken. But even the best ergothioneine food sources are matsutake mushrooms and reishi mushrooms. But even the best food sources, such as matsutake mushrooms and reishi mushrooms, are unable to provide the body with enough nutrients through dietary supplements, and the body is unable to absorb ergothioneine from food fully.
Guanjie Biotech specialises in bio-enzymatic fermentation technology in 2022. We have extracted bulk ergothioneine powder with a purity of 99.9% and scientifically formulated it with high-end natural ingredients. We can produce high-purity Ergothioneine powder.
• Advantages of Ergothioneine
In addition to the above-mentioned effects of ergothioneine that can enter cells to scavenge free radicals, slow down cellular aging and prolong life span. It has excellent performance in many other aspects.
• Slowing down the ageing process
Ergothioneine can enter the mitochondria, the energy factories of cells. It fights free radicals, reduces telomere shortening, protects DNA from oxidative stress damage and maintains the health of cells, tissues and organs. The world's leading medical literature database, PubMed Journal certified views ergothioneine as an anti-aging Top-grade ingredient.
• Antioxidant Power
Ergothioneine is the fifth generation of antioxidants on the market. It is the only antioxidant that can enter the mitochondria of cells. It is the only antioxidant that can enter the mitochondria of cells and scavenge free radicals without disturbing the balance of the original antioxidant defence system.
It has 6,000 times the antioxidant power of vitamin E, 30 times the antioxidant power of coenzyme Q10, 14 times the antioxidant power of glutathione and 6 times the antioxidant power of astaxanthin.
• Protects cardiovascular health
Professor Einar Smith of Lund University in Sweden followed up with 20 years. He measured the plasma metabolism of 3,236 participants without cardiovascular disease and diabetes. The study found ergothioneine in 112 different tested markers. It was the best marker for lower rates of CVD and S death. Ergothioneine (EGT) protects endothelial cells from oxidative and inflammatory damage and forms a vascular barrier.
• Enhancement of body immunity
Bulk ergothioneine powder enhances T-cell activity and promotes the production and release of cytokines. Meanwhile, it can also regulate the proliferation of B cells and the production of antibodies, enhancing the body's immune response.
• Inhibit the production of inflammatory factors
Ergothioneine can inhibit inflammatory factors. Such as the production of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), etc. It reduces the role of inflammatory mediators in the inflammatory process, thus reducing excessive inflammatory response.
• Improvement of sleep quality
Professor Takahiro Ishimoto of the School of Pharmacy at Kanazawa University in Japan conducted a study. He experimented on 92 volunteers with high anxiety and sleep problems. The volunteers took 20mg of ergothioneine or a placebo capsule daily for 4 weeks. He found that ingesting ergothioneine can penetrate the blood-brain barrier and regulate the nerve center through a variety of biological mechanisms, soothing stress, and tightness and improving sleep quality.
• Nervous system protection
By removing oxidative stress damage, ergothioneine protects nerve cells from damage and maintains normal nerve function, helping to prevent and treat Parkinson's disease, Alzheimer's disease, and other neurodegenerative diseases.
• Resisting depression
Ergothioneine may exert its antidepressant effects in the body by promoting neuronal differentiation.
• Skin Anti-Aging
Ergothioneine is also known for its anti-aging effects on the skin, and is used as an ingredient in many major skincare products.
• Anti-wrinkle
Ergothioneine's highly effective anti-oxidant action not only slows down skin aging, but also blocks free radical damage to collagen. It prevents collagen fibres and elastin fibres from further ageing and breaking down. It also promotes collagen synthesis and repairs damaged collagen, making the skin firm and supple.
• Darkening and whitening
Bulk ergothioneine powder blocks the production of melanin and increases the amount of glutathione in the body. The synergistic effect of the two inhibits tyrosinase activity and reduces melanin production and deposition, removing darkness and yellowing from the inside out, resulting in a translucent, glowing and moisturized skin.
Is ergothioneine safe?
In July 2017, EU EU approved L-ergothioneine as a new food ingredient. It can be applied in dietary supplements.In 2018, the EU expanded the use of bulk ergothioneine powder beyond dietary supplements. It can also be applied in common food products such as beverages and cereal bars.

In August 2019, lysergic acid thionine passed GRAS certification by the US Food and Drug Administration FDA. It can be applied in general food, cosmetics, and healthcare products.
In 2020, the Japanese market began to introduce functional indicated foods containing ergothioneine, focusing on improving memory function in the elderly.
In 2022, Health Canada approved ergothioneine as a medicinal/non-medicinal natural health product. In non-medicinal cases, it can be used as an antioxidant, skin conditioner.
On 17 May this year, the National Health Commission released a new food ingredient acceptance announcement, including ergothioneine, the 'longevity vitamin'. As a cosmetic food ingredient, This announcement signals that ergothioneine may usher in a new development in the field of oral anti-aging.
Guanjie Biotech's bulk ergothioneine powder is of high quality and purity. If you are interested in our products, please contact us at info@gybiotech.com.






