Sulforaphane Powder

Sulforaphane Powder Manufacturer in China - Wholesale Sulforaphane Powder

Guanjie Biotech is a premier China-based wholesale sulforaphane powder manufacturer delivering high-purity broccoli sprout extract for global health and supplement brands. Utilizing advanced green water and ethanol extraction, we source sulforaphane precursor-rich brassica vegetables, like cauliflower and broccoli, to maximize enzymatic conversion rates.

Through precise glucoraphanin hydrolysis, our state-of-the-art facility produces international-grade natural sulforaphane extract with exceptional potency and stability. We supply bulk sulforaphane powder in diverse customizable specifications (0.5%, 1%, 10%, 50%, 90%, and 98% purity) to meet strict international OEM formulation standards. Contact Guanjie Biotech for bulk pricing and reliable factory-direct sourcing. If you are interested in our products, please contact us:info@gybiotech.com

Why choose Guanjie Biotech?

1. Free Sulforaphane sample.

2. Sulforaphane powder Factory direct supply, OEM, R&D service is acceptable.

3. Quality certificated: ISO/HACCP/KOSHER/HALAL Certificates.

4. Quality Guarantee: 1 year quality guarantee and resend new one or refund if any quality problems.

5. Fast shipping: Samples delivered by Express and commercial quantity delivered by air or by sea.

 

Certificate of Analysis

Item	Specification	Results
L-Sulforaphane%	0.98%~1.03%	1.01%
Appearance & Color	Yellow Powder	Conform
Loss on drying	≤5%	1.45%
Odor & Taste	Characteristic	Conform
Solvent Residue	Negative	Conform
Total Heavy Metals	≤20.00mg/kg	Conform
Arsenic (As)	≤0.2mg/Kg	Conform
Phosphate Organics	Negative	Conform
Organics Residues	Negative	Conform
DDT	≤0.1mg/Kg	Conform
BHC	≤0.1mg/Kg	Conform
Total Plate Count	≤1000cfu/g	Conform
Total Yeast & Mold	≤100cfu/g	Conform
E. Coli	Negative	Conform
Packing and Storage	Keep container tightly closed. Keep container in a cool, well-ventilated  area. Freeze.
Expiration Date	2 Years When Stored properly

 

Other specifications:

Product Name	Active Ingredients	Standardization
Broccoli Seeds Extract	Sulforaphane	Sulforaphane 1%-95%
		Micro-capsule powder Sulforaphane 1%
		Sulforaphane 1% powder
		Sulforaphane 10% powder
		Sulforaphane 10% oil liquid
	Glucoraphanin	Ratio 10:1, 20:1, 30:1 etc
		Glucoraphanin 13.5%+ Sulforaphane 1% powder
		Glucoraphanin 20% powder
		Glucoraphanin 1% powder
		Glucoraphanin 10% powder
		Glucoraphanin 13% powder

 

 

How Is High-Purity Sulforaphane Powder Produced?

Manufacturing premium sulforaphane powder requires advanced green extraction technology to preserve bioactivity, stabilize active compounds, and yield maximum potency from raw broccoli seed extract.

 

Raw Material Sourcing & Seed Selection

The production process begins at the agricultural source. Selecting elite raw materials-screening over 138 high-yielding broccoli seed (Brassica oleracea var. italica) varieties-ensures rich concentrations of glucoraphanin (the essential precursor to sulforaphane) before processing even starts.

• Supercritical CO2 Degreasing & Enzymatic Self-Transformation

Raw broccoli seeds contain heavy naturally occurring oils that act as a physical barrier, preventing the critical myrosinase enzyme from converting glucoraphanin into active sulforaphane.

• Traditional Method:

Uses harsh chemical solvents like petroleum ether or hexane, leaving behind residual contaminants and yielding cloudy extracts.

• Supercritical CO2 Extraction:

A clean, eco-friendly green technology that removes up to 94% of seed oils while preserving heat-sensitive plant compounds. Optimized parameters include a pressure of 30 MPa, extraction temperature of 40°C, CO2 flow rate of 7 BV/h, particle size of 40 mesh, and a 4-hour extraction duration.

 

Patented Biotransformation:

Once deglazed, a patented enzymatic self-transformation process triggers optimal hydrolysis. This natural enzyme interaction maximizes sulforaphane yield and boosts downstream glucosinolate purification efficiency without compromising Sulforaphane Powder safety.

 

Low-Temperature Extraction & Purification

Because natural sulforaphane extract is sensitive to thermal degradation, a low-temperature extraction and membrane purification protocol is applied. Protecting the active molecule from excess heat yields a standardized, highly stable Sulforaphane Powder supplement ingredient with superior bioavailability and potent antioxidant properties.

 

Quality Control, Analytical Testing & Packaging

Every production batch undergoes rigorous third-party laboratory testing, utilizing HPLC analysis to verify active compound concentration, chemical purity, and heavy metal compliance.

Production Stage	Standard Method	Supercritical CO2 Method	Key Benefit
Defatting / Degreasing	Petroleum Ether / Hexane	Supercritical CO2 (30 MPa, 40°C)	Zero toxic solvent residue; 94% oil removal
Conversion	Chemical Additives	Biotransformation via Myrosinase	Higher yield of bioactive sulforaphane
Purification	High-Heat Evaporation	Low-Temperature Concentration	Maintains long-term bioactive potency

The final pure bulk sulforaphane powder is securely sealed in moisture-proof, light-shielded packaging tailored to meet customized OEM, wholesale, and nutraceutical formulation needs.

 

Why Choose Broccoli as a Source?

Broccoli has a high content of cellulose, so cellulase can be added to hydrolyze the cellulose in the plant cell wall. This enhances the release of radish sulfide as well as black mustard enzyme in the cytoplasm and promotes the sulforaphane Powder.

 

The sulforaphane purification process relies on advanced isolation techniques to yield high-purity sulforaphane powder for dietary supplements, nutraceuticals, and functional foods. Extracted primarily from cruciferous vegetables like broccoli seeds and sprouts, natural sulforaphane requires precise extraction and refinement to maximize its bioactivity and stability.

Leading manufacturers like Guanjie Biotech utilize advanced, scalable testing and purification methods to supply premium sulforaphane bulk powder and wholesale broccoli seed extract Sulforaphane Powder.

 

Key Methods in Sulforaphane Purification & Analysis

Macroporous Resin Adsorption

Macroporous adsorption resins are non-ionic polymer compounds engineered with porous structures and large specific surface areas. This method uses physical adsorption to selectively isolate organic compounds from raw solutions.

● Mechanism:

Target compounds (such as radish sulfide/sulforaphane) selectively bind to the resin bed, separating them from water-soluble impurities.

● Resin Performance:

When testing resins like HP20, SP207, SP850, and HP2MGL for sulforaphane isolation, SP850 resin exhibits superior adsorption and desorption efficiency.

● Yield & Purity:

Reaches Sulforaphane Powder purity up to 85.9%, making it an effective method for large-scale industrial extraction.

 

Silica & Gel Column Chromatography

Column chromatography separates components based on their distinct partition coefficients between a stationary phase and a mobile phase. As the sample passes through the column, repeated partitioning isolates individual bioactive molecules.

● Primary Media:

Silica gel column chromatography and gel column chromatography are standard for sulforaphane extract purification.

● Function:

Effectively removes pigments, lipids, and unwanted plant matter to produce a refined, high-grade sulforaphane concentrate.

 

Reversed-Phase High-Performance Preparative Liquid Chromatography (RP-HPLC):

Preparative RP-HPLC is an essential analytical and purification standard in modern phytochemistry.

● Phase Polarity: Unlike normal-phase liquid chromatography (where the stationary phase is more polar than the mobile phase), reversed-phase liquid chromatography uses a non-polar stationary phase paired with a polar mobile phase.

● Application: RP-HPLC provides exceptionally precise separation, making it indispensable for measuring sulforaphane concentration, validating batch quality, and producing high-purity sulforaphane powder.

 

High-Speed Countercurrent Chromatography (HSCCC):

HSCCC is a support-free, liquid-liquid partition chromatography technique that eliminates solid-matrix irreversible adsorption.

● Solvent System: A biphasic solvent system comprising hexane/ethyl acetate/methanol/water (1:5:1:5, v/v/v/v) is used to purify sulforaphane powder.

● Advantages: Maximizes raw material recovery, preserves sensitive bioactive compounds, and yields purified active sulforaphane without sample loss.

 

Semi-Preparative High-Performance Liquid Chromatography:

Semi-preparative HPLC bridges the gap between analytical testing and commercial production, differing primarily in column inner diameter and mobile phase flow rate.

●Key Strengths:

Offers high sensitivity, superior resolution, and strong recovery rates for enriching sulforaphane compounds.

●Optimization:

While initial yields may vary slightly in purity, fine-tuning chromatographic conditions-such as mobile phase flow rates and precise fraction collection times-consistently improves both total purity and high-yield recovery.

 

What does sulforaphane powder do?

● Supports a Healthier Cardiovascular System

Research shows that people who eat more cruciferous vegetables are less likely to die from heart disease. Sulforaphane in particular has been shown to protect against cardiovascular disease.

 

● Protecting the Brain from Age-Related Diseases

Studies on mice have shown that sulforaphane can prevent dementia in mice with Alzheimer's disease.

 

● Reduces weight gain

Sulforaphane powder blocks fat formation and reduces weight gain. The sulforaphane precursor, sulforaphane, also reduces obesity-induced inflammation and oxidative stress.

 

● Helps improve blood sugar management

In human studies, people with diabetes produced less glucose in their livers when they took concentrated sulforaphane supplements.

 

● Protects and Supports Healthy Skin

Sulforaphane powder protects the skin from the harmful effects of UV radiation. Clinical trials are currently underway to determine whether topical sulforaphane can also reduce skin aging.

 

● Improve brain function

It may help heal traumatic brain injury. Sulforaphane bulk Powder helps increase blood flow to the brain and reduce swelling, and activates the Nrf2 pathway that reduces oxidative stress.

 

● Reduce stomach infections

Sulforaphane reduces H. pylori infection in the stomach of mice, which can lead to stomach infection. Due to its Nrf2-activating properties, broccoli sprouts are also being studied in clinical trials as a drug against H. pylori.

 

● Improve autism

Human clinical trials have shown that sulforaphane powder can significantly improve social interactions, reduce abnormal behavior and improve communication. Some of the families in these studies continued taking the sulforaphane dose even after the trial ended and reported improvement over a longer period of time.

 

● Reduce muscular dystrophy

In a study in mice with muscular dystrophy, sulforaphane powder activated the Nrf2 pathway, which reduced muscle inflammation. In another mouse study, sulforaphane improved muscle function and reduced oxidative stress in already affected muscles.

 

FAQs:

Q1: What is the difference between sulforaphane and glucoraphanin?

Glucoraphanin is an inactive precursor found in cruciferous vegetables, while pure bulk sulforaphane is the bioactive, antioxidant-rich compound produced when myrosinase converts glucoraphanin. Natural sulforaphane powder benefits cellular health, making sulforaphane supplements and broccoli sprout sulforaphane essential for maximum bioactivity.

Q2: Is broccoli sprout extract the same as sulforaphane?

No, broccoli sprout extract is a plant material containing glucoraphanin and myrosinase. Organic sulforaphane is the potent phytonutrient formed after enzymatic conversion. High-quality broccoli extract sulforaphane products deliver this active glucoraphanin-sulforaphane compound directly for targeted health benefits.

Q3: How to Choose: Sulforaphane powder or Sulforaphane capsules?

Choose bulk sulforaphane powder for flexible dosing, custom formulation, and functional beverages. Choose stabilized sulforaphane capsules for portable daily intake and taste protection. Guanjie Biotech offers OEM and ODM solutions for high-quality sulforaphane bulk supply and finished supplements.

Q4: What is the purity of bulk sulforaphane powder?

Bulk sulforaphane powder purities range from standard 0.5% or 1% yields to concentrated 10%, 50%, or 98% standardized extracts. Sourcing pure sulforaphane extract ensures high potency for dietary supplements, health products, and custom commercial sulforaphane manufacturing applications.

Q5: What is the shelf life of sulforaphane extract?

Standard sulforaphane bulk extract maintains a 24-month shelf life when stored in sealed, light-resistant containers away from heat and humidity. Proper storage preserves stable sulforaphane potency, protecting active broccoli sprout extract sulforaphane from degradation over time.

Q6: What is the difference between Natural sulforaphane and synthetic sulforaphane?

Natural sulforaphane powder from broccoli sprouts contains plant co-factors that support optimal sulforaphane bioavailability and absorption. Synthetic sulforaphane is lab-created for high purity without agricultural reliance. Both options serve distinct market needs in the growing global sulforaphane market.

 

Factory&Team：

 

Certification

 

Package & Shipment

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