Sulforaphane Powder

Sulforaphane Powder Supplier:

Guanjie Biotech is a bulk sulforaphane Powder supplier. We use the water/ethanol extract method. We make full use of brassica vegetables such as cauliflower, which is rich in sulforaphane precursors, to increase the conversion rate of sulforaphane. After hydrolysis and other key preparation processes, sulforaphane products with high content and high purity at the international level can be finally formed. We have different specification:0.5%, 1%, 10%, 50%, 90%, 98%, you can choose what you need. If you are interested in our products, please contact us:info@gybiotech.com

Why choose Guanjie Biotech?

1. Free sample for most items.

2. Sulforaphane powder Factory direct supply, OEM, R&D service is acceptable.

3. Quality certificated: ISO/HACCP/KOSHER/HALAL Certificates.

4. Quality Guarantee: 1 year quality guarantee and resend new one or refund if any quality problems.

5. Fast shipping: Samples delivered by Express and commerical quantity delivered by air or by sea.

 

Certificate of Analysis

Item	Specification	Results
L-Sulforaphane%	0.98%~1.03%	1.01%
Appearance & Color	Yellow Powder	Conform
Loss on drying	≤5%	1.45%
Odor & Taste	Characteristic	Conform
Solvent Residue	Negative	Conform
Total Heavy Metals	≤20.00mg/kg	Conform
Arsenic (As)	≤0.2mg/Kg	Conform
Phosphate Organics	Negative	Conform
Organics Residues	Negative	Conform
DDT	≤0.1mg/Kg	Conform
BHC	≤0.1mg/Kg	Conform
Total Plate Count	≤1000cfu/g	Conform
Total Yeast & Mold	≤100cfu/g	Conform
E. Coli	Negative	Conform
Packing and Storage	Keep container tightly closed. Keep container in a cool, well-ventilated  area. Freeze.
Expiration Date	2 Years When Stored properly

 

Other specifications:

Product Name	Active Ingredients	Standardization
Broccoli Seeds Extract	Sulforaphane	Sulforaphane 1%-95%
		Micro-capsule powder Sulforaphane 1%
		Sulforaphane 1% powder
		Sulforaphane 10% powder
		Sulforaphane 10% oil liquid
	Glucoraphanin	Ratio 10:1, 20:1, 30:1 etc
		Glucoraphanin 13.5%+ Sulforaphane 1% powder
		Glucoraphanin 20% powder
		Glucoraphanin 1% powder
		Glucoraphanin 10% powder
		Glucoraphanin 13% powder

 

 

How Is Sulforaphane Powder Produced?

1. Raw Material:

Processing 138 types of broccoli seed preferred, from the source, to ensure the quality of the sulforaphane powder product.

2. Degreasing. 

Patented technology of organism self-transformation ensures the safety and high yield of the sulforaphane powder product.

Broccoli seeds contain a large amount of oil that hinders the contact of the mustard enzyme with the thioglucoside. Therefore, the seeds are degreased before enzymatic digestion. Organic solvents such as hexane and petroleum ether are often used for degreasing.

Supercritical CO2 extraction was applied to the degreasing process of broccoli seeds and compared with the traditional degreasing with petroleum ether. It was found that the extract was more turbid when petroleum ether was used for degreasing, while the supercritical degreasing method yielded a higher oil yield. The rate of radish sulforaphane yield was also higher. The supercritical CO2 extraction process was optimized to remove 94% of the oil in broccoli seeds. The optimized results were as follows: extraction pressure 30 MPa, The optimized results were as follows: extraction pressure 30 MPa, CO2 flow rate 7 BV/h, pulverized particle size 40 mesh, and extraction time 4 h. The extraction temperature was 40 ℃. The optimized results were as follows: extraction pressure 30 MPa, CO2 flow rate 7 BV/h, pulverized particle size 40 mesh, extraction time 4 h, and extraction temperature 40 ℃, which was conducive to the purification of radish thiols in the later stage.

 

3. Extraction and purification:

The low-temperature extraction and purification process makes the sulforaphane powder product's efficacy ingredient content higher and more stable

4. Testing, packaging:

● The last gate is well taken and strict testing standards are followed.

● A variety of packaging specifications to meet all your needs

 

Why Choose Broccoli As Source?

Broccoli has a high content of cellulose, so cellulase can be added to hydrolyze the cellulose in the plant cell wall. This enhances the release of radish sulfide as well as black mustard enzyme in the cytoplasm and promotes the sulforaphane Powder.

 

Purification Process Of Sulforaphane:

A variety of methods have been developed, including large pore resin adsorption, column chromatography, reversed-phase high performance preparative liquid chromatography, high-speed countercurrent chromatography, semi-preparative high-performance liquid chromatography, and so on. Guanjie Biotech uses the following methods to test sulforaphane powder.

 

● Macroporous resin adsorption method 

Macroporous adsorption resin is a new type of non-ionic polymer compound with a porous nature and large specific surface area. Through physical adsorption, organic substances are selectively adsorbed from the solution to achieve the purpose of separation and purification. The researchers used the adsorption method of macroporous resins to realize the separation and purification of radish sulfide, and compared the adsorption and desorption performance of radish sulfide on several kinds of macroporous resins, including HP20, SP207, SP850 and HP2MGL. The results showed that the SP850 resin was the best for the separation of radish sulfide, and the purity of radish sulfide was 85.9%.

 

● Column chromatography 

Column chromatography, also known as column chromatography, is mainly based on the different partition coefficients of the components in the sample mixture between the stationary phase and mobile phase, and the sulforaphane powder components are separated by repeated partitioning. In the sulforaphane powder purification of radish sulfide, silica gel column chromatography and gel column chromatography are mainly used.

 

● Reversed-phase high performance preparative liquid chromatography (RP-HPLC) 

High-performance liquid chromatography (HPLC) is a new separation and analytical technique developed on the basis of classical liquid chromatography and gas chromatography. 

HPLC is a new separation and analytical technique based on classical liquid chromatography and gas chromatography. Depending on the polarity of the stationary phase and mobile phase, it can be divided into normal-phase HPLC and reversed-phase HPLC. In normal-phase HPLC, the polarity of the stationary phase is greater than that of the mobile phase. In reversed-phase liquid chromatography, the sulforaphane powder polarity of the stationary phase is smaller than that of the mobile phase, while in reversed-phase liquid chromatography, the polarity of the stationary phase is smaller than that of the mobile phase. The application of reversed-phase HPLC is becoming more and more widespread, and it occupies an important position in HPLC.

 

● High Speed Countercurrent Chromatography (HSCCC) 

High-speed countercurrent chromatography (HSCCC) is a new type of continuous high-efficiency liquid-liquid chromatography developed based on countercurrent chromatography (CCC).

It is widely used for the separation and purification of various natural products and synthetic products. The purification of sulforaphane powder was carried out by hexane/ethyl acetate/methanol/water (1:5:1:5, v/v/v/v) system in high-speed countercurrent chromatography (HSCCC).

 

● Semi-preparative high performance liquid chromatography 

Semi-preparative high performance liquid chromatography (HPLC) is a type of preparative liquid chromatography, the main difference is the flow rate and the inner diameter of the column. The semi-preparative HPLC method has the advantages of high sensitivity, good separation and high recovery for the purification and enrichment of radish sulfide. Although the purity of the obtained sulforaphane powder was slightly lower, it could be improved by optimizing the chromatographic conditions and precise collection time of radish sulfide, which was easier to improve than the low recovery.

 

What does sulforaphane powder Do?

● Supports a Healthier Cardiovascular System

Research shows that people who eat more cruciferous vegetables are less likely to die from heart disease. Sulforaphane in particular has been shown to protect against cardiovascular disease.

 

● Protecting the Brain from Age-Related Diseases

Studies on mice have shown that sulforaphane can prevent dementia in mice with Alzheimer's disease.

 

● Reduce weight gain

Sulforaphane powder blocks fat formation and reduces weight gain. The sulforaphane precursor, sulforaphane, also reduces obesity-induced inflammation and oxidative stress.

 

● Help improve blood sugar management

In human studies, people with diabetes produced less glucose in their livers when they took concentrated sulforaphane supplements.

 

● Protect and Supports Healthy Skin

Sulforaphane powder protects the skin from the harmful effects of UV radiation. Clinical trials are currently underway to determine whether topical sulforaphane can also reduce skin aging.

 

● Improve brain function

It may help heal traumatic brain injury. Sulforaphane bulk Powder helps increase blood flow to the brain and reduce swelling, and activates the Nrf2 pathway that reduces oxidative stress.

 

● Reduce stomach infections

Sulforaphane reduces H. pylori infection in the stomach of mice, which can lead to stomach infection. Due to its Nrf2-activating properties, broccoli sprouts are also being studied in clinical trials as a drug against H. pylori.

 

● Improve autism

Human clinical trials have shown that sulforaphane powder can significantly improve social interactions, reduce abnormal behavior and improve communication. Some of the families in these studies continued taking the sulforaphane dose even after the trial ended and reported improvement over a longer period of time.

 

● Reduce muscular dystrophy

In a study in mice with muscular dystrophy, sulforaphane powder activated the Nrf2 pathway, which reduced muscle inflammation. In another mouse study, sulforaphane improved muscle function and reduced oxidative stress in already affected muscles.

 

Factory&Team：

 

Certification

 

Package & Shipment

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