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Urolithin A 99%

Name: China Urolithin A 99% Manufacturers Suppliers Factory - Wholesale Urolithin A 99% for Sale - Guanjie Biotech
Brand: Guanjie Biotech
SKU: 241916391

Specification: 99%
Appearance:Off-white to yellow powder
CAS NO:1143-70-0
Test method: HPLC
Two Factories & Three production lines
GMP standard workshop & two independent laboratories
FDA Cert.
Certifications: Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,SC
Overseas warehouse(NJ,USA)
Provide Free Sample
MOQ: 1KG
Not for Private Person Sale

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Description

Urolithin A 99% Supplier | Natural Urolithin A Ingredient for Capsules and Tablets

Guanjie Biotech is a professional Urolithin A 99% Powder supplier specializing in high-purity bulk Urolithin A ingredients for dietary supplements and nutraceutical formulations. Our bulk Urolithin A powder features a 99% assay and is suitable for capsule, tablet, and functional nutrition applications. As an experienced Urolithin A manufacturer and supplier, we provide consistent quality, competitive pricing, and reliable supply. With strict quality control and professional service, Guanjie Biotech helps global customers obtain premium Urolithin A supplement raw materials for their products.

COA

Items	Specifications	Test Results	Method
Appearance	Off-white to yellow powder	Light yellow powder	Visual
Identification	The spectrum corresponds to the reference	Conforms	HNMR
Purity	NLT 98.0%	98.9%	HPLC
Water	NMT 1.0%	0.3%	USP<921>
Residue on ignition	NMT 1.0%	0.15%	USP<281>
Heavy Metals	NMT 20 ppm	Conform	USP<231>
Arsenic	NMT 2ppm	Conforms	ICP-MS
Lead	NMT 2ppm	Conforms	ICP-MS
Microbiological Tests
Total Plate Count	NMT 1000cfu/g	Conforms	USP<2021>
Yeast & Mold	NMT 100cfu/g	Conforms	USP<2021>
E. Coli.	Negative in 10g	Negative	USP<2022>
Salmonella	Negative in 10g	Negative	USP<2022>
Packing	Sealed export grade drum & double of sealed plastic bag.
Conclusion	Product Conforms to Specifications
Storage	Store in cool and dry place, keep away from strong light and heat.

How Is Urolithin A 99% produced?

Urolithin A 99 powder flow chart

what is Testing standards of Urolithin A?

Testing standards for Urolithin A 99% typically include purity testing, impurity analysis and content determination. These criteria ensure that the product meets the quality requirements.

1. Purity testing -High Performance Liquid Chromatography (HPLC):

HPLC is the main method to detect the purity of urolithin A. The standard requires the purity of urolithin A to be determined by HPLC. The standard requirement is that the purity of urolithin A should be more than 98%.

2. Impurity analysis:

- Gas chromatography-mass spectrometry (GC-MS):

For the detection and identification of volatile impurities and organic impurities in urolithin A.

- Liquid chromatography-mass spectrometry (LC-MS):

For the detection and identification of non-volatile impurities and complex organic impurities.

3. Content determination:

- Ultraviolet-visible spectrophotometry (UV-Vis):

Used for the preliminary determination of urolithin A. The concentration of urolithin A is estimated by measuring the absorbance of the sample.

- Nuclear Magnetic Resonance (NMR):

Accurate determination of Urolithin A 99 content by analysing its hydrogen or carbon spectrum.

How To Test Urolithin A?

At Guanjie Biotech, ensuring our Urolithin A is 99% pure and of the highest quality is our top priority. We use a team of advanced laboratory instruments, each with a special job, to confirm the identity, purity, and strength of every batch.

High Performance Liquid Chromatography (HPLC):
HPLC is our primary tool for measuring purity. We dissolve the Urolithin A sample and inject it into a machine that pushes it through a very fine tube (called a column) with a special packing. Different substances travel through this tube at different speeds.

How it works: We use a liquid mixture to carry the sample and shine an ultraviolet light at a specific wavelength (310 nm) to detect Urolithin A as it exits the tube.

The Result: By measuring how long it takes for the Urolithin A to appear (its retention time) and the size of the peak it creates, we can precisely calculate its purity percentage, ensuring it meets the 99% standard.

Liquid Chromatography-Mass Spectrometry (LC-MS):
LC-MS is a powerful combination that builds on HPLC. First, it separates the sample, and then it tells us the exact weight (mass) of each molecule coming out.

How it works: After separation, the Urolithin A is directed into a mass spectrometer, which acts like a molecular scale. It measures the mass-to-charge ratio, creating a unique fingerprint for the Urolithin A molecule.

The Result: This confirms that the molecule we are measuring is definitely Urolithin A and not something else. It also helps us identify any tiny impurities present, guaranteeing the product's identity and quality.

Gas Chromatography-Mass Spectrometry (GC-MS):
GC-MS is another technique used to find and identify very small, volatile impurities. Since Urolithin A isn't naturally suited for this method, we first prepare it through a process called derivatization.

How it works: The prepared sample is vaporized and carried by helium gas through a column. The separated components then enter a mass spectrometer for identification.

The Result: By comparing the results to a massive library of known compounds, we can pinpoint exactly what any minor impurities are, ensuring they are within safe and acceptable limits.

Ultraviolet-Visible Spectrophotometry (UV-Vis):
UV-Vis is a straightforward and reliable method for determining concentration. It works on the principle that Urolithin A absorbs light at a specific wavelength (310 nm).

How it works: We prepare solutions of known concentrations and measure how much light they absorb to create a standard curve. We then test our sample and compare its absorbance to this curve.

The Result: This gives us a quick and accurate measurement of how much Urolithin A is present in a given sample, confirming its potency.

Market Potential of Urolithin A

1. Powerful functions

- Significant anti-aging effects:

Uricetin A powder has been proven in studies to have a variety of health benefits such as slowing down aging and enhancing mitochondrial function. These functions make it unique among anti-aging products.

- Multi-field application:

In addition to anti-aging, Urolithin A 99% has anti-inflammatory and anti-cancer properties. This increases the market demand.

2. Market demand continues to grow

- Health and wellness trend:

As people's health awareness increases, the market demand for anti-aging products continues to grow. As a powerful natural anti-aging ingredient, urolithin A has a broad market prospect.

- High-end market demand:

High-purity and high-efficiency urolithin A powder products have great potential in the high-end health care and beauty care markets.

3. Scientific and Clinical Support

- Clinical Research:

The efficacy of urolithin A 99% powder has been verified in a number of clinical studies. This provides strong support for its marketing.

- Scientific Collaboration:

Collaboration with research institutes and universities can further promote the research and application of urolithin A and enhance market confidence.

Is Urolithin A Safe?

The safety of Urolithin A 99 has been verified through several scientific studies and clinical trials.

1. Animal studies:

- Toxicity studies:

Several animal studies have shown that urolithin A does not exhibit significant toxicity at high doses and long-term use. Mice and rats ingested high doses of urolithin A in experiments and did not show significant toxic reactions or organ damage.

- Dose Dependence:

The physiological effects of Urolithin A 99% were found to be relatively mild in animals at different doses. They did not exhibit acute toxicity or chronic toxicity.

2. Human clinical trials:

- Short-term studies:

In short-term clinical trials, no serious adverse effects were reported in healthy volunteers after ingestion of urolithin A. Study participants were in good health with stable physiological parameters during the observation period.

- Long-term studies:

Although there are relatively few long-term clinical trials, the available long-term studies also did not find significant negative effects of urolithin A on human health.

3. Metabolic studies:

- Metabolic pathway:

Urolithin A is mainly produced by intestinal bacteria through the metabolism of the precursor substance ellagic acid. Its metabolic pathway is relatively clear in the human body, and no toxicity of metabolites has been found.

- Excretion pathway:

Urolithin A 99% and its metabolites are mainly excreted through urine. The metabolic pathway is normal, and there is no cumulative toxicity.

Urolithin A Formulation Guide for Capsules, Tablets, and Nutraceutical Products

Urolithin A is an emerging nutraceutical ingredient widely used in dietary supplements, functional nutrition products, and health formulations. For manufacturers developing Urolithin A capsules, tablets, and powder blends, proper formulation design is essential to ensure ingredient stability, dosage accuracy, product quality, and consumer acceptance.

● Selecting High-Purity Urolithin A Raw Material

The quality of the raw material directly affects the performance of the final supplement. Manufacturers should choose Urolithin A powder with high purity, consistent assay results, and complete quality documentation, including COA, MSDS, and specification sheets.

For premium supplement formulations, Urolithin A 99 powder is commonly selected because its high assay provides better control over dosage accuracy and formulation consistency. A reliable bulk Urolithin A supplier should provide stable supply, strict quality testing, and batch-to-batch consistency.

● Urolithin A Capsule Formulation Considerations

Capsules are one of the most common delivery formats for Urolithin A supplements. During capsule development, formulators need to consider ingredient compatibility, flowability, dosage size, and excipient selection.

Urolithin A powder can be combined with suitable excipients such as microcrystalline cellulose, starch, or other approved fillers to improve powder flow and capsule filling efficiency. Particle size optimization is also important to ensure uniform distribution and accurate dosing.

For clean-label supplement products, manufacturers may choose natural excipients and minimize unnecessary additives to meet consumer demand for transparent ingredient lists.

● Urolithin A Tablet Formulation Guide

Tablet production requires careful consideration of compression properties and stability. During the tableting process, formulators should evaluate powder density, moisture content, binding agents, and disintegration characteristics.

A well-designed Urolithin A tablet formulation should maintain ingredient uniformity while ensuring appropriate hardness and dissolution performance. Proper manufacturing parameters help prevent issues such as tablet cracking, poor compression, or inconsistent active ingredient distribution.

FAQs:

Q1: What is the difference between Urolithin A and pomegranate extract?

Pomegranate extract contains ellagitannins and other polyphenols, while Urolithin A is a specific metabolite generated from ellagitannin compounds. Urolithin A powder provides a standardized active ingredient with defined purity, making it easier for supplement manufacturers to control formulation dosage.

Q2: How should Urolithin A powder be stored?

Urolithin A powder should be stored in a cool, dry place away from direct sunlight, moisture, and excessive heat. For industrial applications, bulk Urolithin A ingredients should be sealed in suitable packaging to maintain stability during transportation and storage.

Q3: Can Urolithin A powder be used for OEM and ODM supplement production?

Yes. Urolithin A 99% powder can be used for OEM and ODM supplement manufacturing, including capsules, tablets, powder blends, gummies, and functional nutrition products. Ingredient suppliers can provide customized specifications, packaging options, and technical documentation according to customer requirements.

Q4: Why is your Urolithin A 99% Powder a better choice for supplement manufacturers?

Our Urolithin A 99% Powder is produced with strict quality control to ensure high purity, consistency, and batch-to-batch stability. It is suitable for capsules, tablets, gummies, and functional nutrition formulations. Each batch is tested with professional analytical methods to verify purity and quality.

Q5: What makes your Urolithin A ingredient different from other suppliers?

Our Urolithin A ingredient focuses on high purity, reliable sourcing, and standardized production. The Urolithin A 99% Powder provides a consistent active compound level, helping supplement brands develop stable formulations with accurate dosage control and reliable product performance.

Q6: How do you ensure the quality and purity of Urolithin A Powder?

We use strict quality management procedures from raw material evaluation to finished product testing. Advanced analytical methods are applied to confirm Urolithin A 99% purity, appearance, and other quality parameters before shipment.

Company Advantages:

Guanjie Biotech's factory is fully qualified. We have many kinds of SC extract production licenses, carry out the record production of traditional Chinese medicine extracts, and are the record manufacturer of export food production. We have various quality, HALAL and KOSHER certificates. The facilities and equipment are standardized, and the production quality management system is complete.

We have a complete testing capacity, technology, production, and quality team. We can provide customized products with various active ingredients for customers' Urolithin A 99% powder-specific business and usage needs. At the same time to meet the high-end customer factory inspection, extended audit, and filing needs.

Factory&Team