Wheat Germ Extract Spermidine

Wheat Germ Extract Spermidine Supplier:

Guanjie Biotech is a professional wheat germ extract spermidine manufacturer and supplier. We provide spermidine in white powder, which has excellent water solubility. The purity standard of our products is high, which can reach a 98% purity level, and we also provide 1.0% specification. And we offer customized services. It includes different purity and packaging specifications and so on. In addition, we also offer the service of filling bulk spermidine powder into capsules. If you are interested in our products or have specific needs, please feel free to contact us: info@gybiotech.com.

 

COA:

Test Items	Specification	Result	MOA
Appearance	White to off-white power	Off-White Powder	Visual
Purity	≥98%	99.0%	GC
Solubility	Soluble in water	Conform	CP2020
Loss on drying	≤1.0%	0.28%	CP2020
Residue on ignition	0.2%	0.02%	CP2020
Ethanol(GC)	5000ppm	600ppm	GC
Heavy Metal Content
Pb	≤0.1 ppm	Conform	GB5009
Hg	≤0.1ppm	Conform	GB5009
Cd	≤0.2 ppm	Conform	GB5009
As	≤0.1ppm	Conform	GB5009
Total microbial count	≤500CFU/g	<10	GB4789
Coliform	≤0.92MPN/g	Conform	GB4789
Mold and yeast	≤50CFU/g	Conform	GB4789
Staphylococcus aureus	0/25g	Conform	GB4789
Salmonella	0/25g	Conform	GB4789
Conclusion	All inspection items conform with the specifications.
Storage Condition	Sealed packaging, stored at cool, dry and away from light.

 

What Are the Advantages of Wheat Germ Extract Spermidine?

Wheat germ extract spermidine powder is a type of anti-aging product. The benefits of anti-aging powders usually depend on their composition, bioavailability, safety, and effectiveness. The following are the possible benefits of wheat germ spermidine extract as compared to other anti-aging powders:

• High bioavailability

Wheat germ extract spermidine bulk powder undergoes special treatment. Such as microencapsulation or nanotechnology to improve its absorption in the body. This improves its anti-aging effect by delivering the active ingredients to the target cells more effectively than some traditional anti-aging powders.

 

• Unique active ingredients

Spermidine wheat germ powder contains one or more unique active ingredients. These ingredients are not commonly found in other anti-aging powders. These ingredients may have specific anti-aging mechanisms. For example, they promote collagen production, inhibit free radical production or activate cell regeneration.

 

• Scientifically Proven Results

Compared to other anti-aging powders, wheat germ extract spermidine powder may have more scientific studies supporting its anti-aging effects. These studies include clinical trials, in vitro experiments, and animal model studies that prove its safety and effectiveness.

 

• Comprehensive anti-aging effects

Spermidine powder may have a multifaceted anti-aging effect. This includes antioxidant, anti-inflammatory, promoting cell regeneration and protecting DNA from damage. This comprehensive mechanism of action could be more effective in combating multiple aspects of aging.

 

• Stability and safety

Spermidine bulk may have been manufactured using advanced technology to ensure the stability and safety of its ingredients. The powder also maintains its activity and effectiveness during storage and transportation.

 

• Easy to formulate and apply

Compared to other anti-aging powders, wheat germ bulk extract may be easier to mix with other ingredients. It is suitable for various product formulations such as creams, oral supplements or beverages.

 

7. User-friendly dosage form

Wheat germ extract spermidine powder is available in user-friendly dosage forms. Such as easily available spermidine bulk powder or capsule, it can be easily carried by consumers.

 

How safe is spermidine?

Safety trials of wheat germ extract spermidine powder have focused on its potential toxicity and effects as a dietary supplement. The following are some relevant safety trials and studies:

• In vitro genotoxicity assay:

In one study, in vitro genotoxicity testing was performed on spermidine-3HCl Powder, a highly purified form of spermidine trihydrochloride. This included a bacterial revertant mutation test and a mammalian micronucleus assay to assess potential genotoxicity.

 

• 90-day oral toxicity study:

Also in this study, a 90-day oral toxicity study was conducted. The researchers tested rats using spermidine-3HCl. It was found that up to the highest tested dose of 12,500 ppm, the subchronic unobserved adverse effect level (NOAEL) was 728 mg/kg bw/day.

 

• Human clinical trials:

Ongoing human clinical trials are evaluating the safety and efficacy of wheat germ extract spermidine powder in the treatment of hypertension, depression, aging of the immune system, and oral mucositis.

 

• Comprehensive reviews of safety and health effects:

A study synthesizes the latest findings on the safety, health effects, absorption and metabolism of spermidine. This describes the progress of raw material evaluation, physicochemical processing, biological processing and other food processing aspects of spermidine.

 

• Anti-aging properties of spermidine:

In another study, the multiple effects of spermidine on longevity and diseases of aging are examined, as well as its safety.

 

• Clinical trials on cardiovascular disease and quality of life:

Additional studies are evaluating the potential effects of spermidine wheat germ extract in myocardial infarction and cardiovascular disease, as well as quality of life.

 

Spermidine Trihydrochloride vS Spermidine

Spermidine trihydrochloride and spermidine are chemically the same substance. However, their forms and application scenarios may differ. Spermidine is a polyamine compound that occurs naturally in living organisms. It plays an important role in cell growth, division, proliferation, and differentiation. And spermidine trihydrochloride is the hydrochloride form of wheat germ extract spermidine powder. It is commonly used in laboratory research or as a form of dietary supplement.

 

• Chemical Structure and Properties

Spermidine has the chemical formula C7H19N3 and contains a long-chain carbon skeleton with several amino (NH2) groups attached. This structure gives spermidine its basic properties. This is because its amino groups can accept protons (H+) to form positively charged ions. Spermidine is usually found as a free base in living organisms. It can bind to DNA, affect gene expression, and participate in a variety of intracellular signaling processes.

Spermidine trihydrochloride, on the other hand, is a salt formed by the reaction of spermidine with hydrochloric acid. This form of spermidine contains three additional chloride ions (Cl-). This makes it more stable and soluble in aqueous solutions. Spermidine trihydrochloride is usually found in the form of white crystals. It can be used in the laboratory to prepare spermidine solutions or as an ingredient in dietary supplements.

 

• Biosynthesis and Metabolism

Spermidine is synthesized in living organisms from putrescine (putrescine) and adenosylmethionine (SAM, S-adenosylmethionine) through a series of enzymatic reactions. This process involves several key enzymes. These include spermidine synthase. It catalyzes the reaction between putrescine and SAM to form spermidine and S-adenosylhomocysteine (SAH).

 

• Applications

Spermidine has a wide range of applications in biomedical research. Due to its role in cellular autophagy, aging and a variety of diseases. Wheat germ extract spermidine powder is used as a tool to study cell biology and pathology. For example, spermidine induces cellular autophagy. This is an internal cellular clearance mechanism that helps cells remove damaged organelles and proteins and maintain cellular health.

Spermidine trihydrochloride is used as a stabilized form of spermidine. It is often used in laboratories to prepare standard solutions for precise measurements and experimental manipulations. In dietary supplements, spermidine in the form of spermidine trihydrochloride can be used to replenish spermidine levels in the body with a view to achieving effects such as anti-aging and improving cardiovascular health.

 

• Safety and Dosage

Some studies have shown that wheat germ extract spermidine powder supplementation has health benefits. However, dosage and individual differences need to be considered. Excessive amounts of spermidine may lead to cytotoxicity, as it can affect the pH balance and redox state within cells.

 

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