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Bacopaside Powder

Bacopaside Powder

Product name: Bacopa Monnieri Extract
Purity: 20%~50%
Appearance: Yellow Brown powder
Mesh Size: 100% pass 80 mesh
Test Method: HPLC
Two Factories & Three production lines
Certifications: Halal,ISO9001,PAHS Free,NON-GMO,KOSHER,HACCP,SC
Delivery term: DHL, FEDEX, Air freight,Sea freight
Provide Free Sample
MOQ: 1KG
Not for Private Person Sale

Description

Bacopa Monnieri Extract Bacopaside powder Supplier:

Guanjie Biotech's Bacopaside powder is a yellow-brown powder with a 100% pass 80 mesh. And we have different specifications:20%-50%. Each batch of Bacopaside bulk Powder product can be tested by the HPLC method, which ensures purity. If you are interested in our product, welcome to enquire with us: info@gybiotech.com.

Bacopa Monnieri Extract Bacopaside Powder

COA:

Examination Items

Examination Standards

Result

Method

Botanical Name

Plant Part Used

Extraction Solvents

Appearance

Part extracted

Bacopa monnieri (L.) Wettst.

Whole herb

Ethanol & Water

Yellow brown powder

Entire herb

Complies

Complies

Complies

Complies

Complies

/

/

/

Visual

Particle size

Loss on drying

Ash

Heavy metals

As

Pb

Solvent residue

100% pass 80 mesh

5.0% max

8.0% max

20.0ppm max

2ppm max

2ppm max

USP standard

Complies

4.1%

3.2%

Complies

Complies

Complies

Complies

USP Particle Size

USP<731>

USP<561>

USP<231>method III

AAS

AAS

USP<467>

Phytochemical analysis

     

Bacopasides

20.0% min

22.7%

HPLC

Microbiological analysis

     

Total bacterial count

Molds& yeast count

Staphylococcus aureus

Salmonella

E. Coli

10000cfu/g max

1000cfu/g max

Negative

Negative

Negative

Complies

Complies

Not Detected

Not Detected

Not Detected

 

 

CP2010&USP

Packing: 25kg/drum.

Storage: Store in a well-closed container at room temperature, protect from light, moisture and pest infestation

Shelf life: 3 years. Non-GMO.

Testing result: It is tested according to the Enterprise Standard, and the result conforms to the Regulation.

 

What Is Bacopaside Powder?

Bacopa Monnieri is a medicinal plant. It is rich in nutrients. Its young stems, leaves and flowers are edible. It is a healthy vegetable and a good quality green medicinal fodder. Bacopaside powder is very important for the food industry and it has a wide range of pharmacological properties. These properties are related to the multiple chemical constituents of Amaranthus, including flavonoids, alkaloids, polysaccharides, fatty acids, terpenoids, sterols, proteins, vitamins and minerals. Polysaccharides are the main active constituents in Amaranthus, and Amaranthus polysaccharide is a biologically active herbal polysaccharide isolated from Amaranthus.

 

What Is The Use Of Bacopa Powder?
Immune Enhancement  Bacopaside powder

• Immune Enhancement

Bacopaside powder has immune-enhancing effects. It has been found that Bacopaside bulk powder can increase the phagocytosis of macrophages and release related immunity factors to enhance the immune activity of macrophages. Moreover, Bacopa Monnieri Extract effectively increased the level of humoral and cellular immunity in tumour-bearing mice, as well as the possible molecular mechanism of immune enhancement. And it is an effective adjuvant nutritional supplement for DC vaccines. Amaranthus polysaccharide-treated antigen had a promotive effect on the immune function of mice. Also, it can be used as a novel immune adjuvant in combination with a DC vaccine for breast cancer treatment. Pectin-like polysaccharides were extracted from amaranth and other herbs, respectively. It has been shown that this polysaccharide can increase the release of IL-6 through PP-mediated bone marrow cell proliferation. This could exert intestinal immunomodulatory activity. It is noteworthy that Bacopaside Powder is effective in activating normal immune cells.

•Anti-tumour

The good anticancer activity of Bacopaside Powder has attracted increasing attention from scholars. It is found that amaranth polysaccharide has good anti-tumour activity, can inhibit the growth of cervical cancer cells in vitro and in vivo. It also has a protective effect against tumour-induced apoptosis in intestinal DC by activating the TLR4-PI3K/AKT-NF-κB signalling pathway in a concentration- and time-dependent manner. Covalent selenation of selenated Amaranthus polysaccharide PPS was able to incorporate inorganic selenium into the final PPS product and change its monosaccharide composition. And it can have colon nutritional and anticancer effects. It was found that the amaranth polysaccharide can effectively inhibit cell malignant proliferation, so that the cells show obvious apoptosis and are dose-dependent. Bacopa Monnieri Extract was found that Amaranthus polysaccharide mainly induced G1 phase cycle block. It induced apoptosis. In addition, the study was conducted by determining the tumour size and body weight changes in U14 mice in vivo. The results showed that amaranth polysaccharides can effectively inhibit the growth of tumours in vivo. Some of the amaranth polysaccharide fractions significantly increased the body weight of the mice.

pure Bacopaside Powder
natural Bacopaside powder

•Hypoglycaemic

Amaranth polysaccharide has a hypoglycemic effect. It is the best food for diabetic patients. Role of voltage-gated sodium channels in Amaranthus polysaccharides and their mechanism related to insulin secretion. Bacopaside powder induced insulin secretion from insulin-secreting β-cell lineage cells (INS-1). Demonstrate the potential of Amaranthus polysaccharides as a therapeutic agent for diabetes mellitus and VGSC as a therapeutic target for diabetes mellitus. The study showed that Amaranthus polysaccharide has significant pharmacological effects on diabetic rats. It was able to reduce the fasting blood glucose level and increase the fasting serum insulin level and insulin sensitivity index value in rats. In addition, the polysaccharide was able to effectively reduce the levels of TNF-α and IL-6, as well as the activities of MDA and SOD in rats. This suggests that the antidiabetic effect of CPOP may be related to its antioxidant and anti-inflammatory effects.

•Anti-inflammatory

Diseases are often accompanied by inflammation. Numerous studies have demonstrated the anti-inflammatory activity of polysaccharides from Amaranthus communis, and the levels of COX-2 protein and STAT3 phosphorylation were elevated in colitis and decreased after treatment with Amaranthus communis. It was reduced after treatment with amaranth. This shows that these two proteins are closely related to the protective effect of Bacopaside powder. Amaranth has some anti-inflammatory effects. Bacopaside powder could alleviate DSS-induced intestinal inflammation by inhibiting the expression of TLR4 and its downstream key proteins MyD88 and NF-κB, inhibiting the maturation of intestinal DCs, balancing the T-lymphocyte subpopulations, and regulating the levels of inflammatory factors in the intestinal mucosa of UC mice. In addition, it can also improve DSS-induced intestinal dysbiosis.

Anti-Inflammatory

 

Regulation News

•China

In 2002, the Ministry of Health of China included Amaranth in the list of articles which are both food and drugs in the notice on further standardising the management of health food raw materials.

In 2022, Q/AFJX 0120 S-2022 made clear provisions on organoleptic requirements, physicochemical indexes, test methods and test rules when horsetail amaranth  Bacopaside Powder is used as a raw material for health food.

 

•European Union

In the European Union, the use of food additives and new food ingredients is strictly regulated by the Food Law of the European Parliament and of the Council (EC 178/2002). As a novel ingredient, the use of amaranth polysaccharides in the EU requires a risk assessment and approval by the European Food Safety Authority (EFSA). Currently, Bacopaside powder is not widely used in food or nutraceuticals in the EU. This may be because the approval process for its use as a novel food ingredient is still ongoing.

 

•United States

In the United States, the Food and Drug Administration (FDA) regulates food ingredients and dietary supplements very strictly. If amaranth polysaccharide is used as a dietary supplement ingredient, it must go through the FDA's 'GRAS' (Generally Recognised as Safe) approval process. In addition, if Bacopa Monnieri Bacopaside are incorporated into a drug, it is subject to a more stringent New Drug Application (NDA) process.

 

•Other regions

Amaranth has a long history of use as a traditional medicinal herb and food ingredient in Asian countries such as Japan and Korea. However, specific applications of Bacopaside powder are still subject to food and drug regulations in the respective countries. In addition, research on plant polysaccharides in these countries is relatively mature. In the future, restrictions on bacopaside may be gradually relaxed in terms of regulations.

 

Our factory:

factory

 

Certification

We have obtained the NON-GMO by Pony test international group. And we get the certifications about HALAAL,ISO 9001,ISO 22000,Kosher, PAHS,SC and so on.

cert.

 

Package&Warehouse:

packing &shipment

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