Products

Mulberry Leaf Extract Powder

Name: China Mulberry Leaf Extract Powder Manufacturers Suppliers Factory - Wholesale Service - Guanjie Biotech
Brand: Guanjie Biotech
SKU: 286408697

Active Ingredient:1-Deoxynojirimycin≥5.0%
Color Deep Brown Fine Powder
Particle Size:100% Pass 80 mesh
Two Factories & Three production lines
GMP standard workshop & two independent laboratories
Certifications: HACCP,Halal,ISO9001,PAHS Free, NON-GMO,KOSHER,SC
Delivery term: DHL, FEDEX, Air freight, Sea freight
Provide Free Sample
MOQ:1KG
Not for Private Person Sale

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Description

Mulberry Leaf Extract Powder Supplier:

Guanjie Biotech is a mulberry leaf extract powder supplier. The key active component in this extract is Deoxynojirimycin (DNJ). Using High-Performance Liquid Chromatography (HPLC) for precise measurement, the product is guaranteed to contain a DNJ assay of 5.0% or higher. It is 100% passes through an 80-mesh screen. This specification confirms its quality as a professionally standardized ingredient suitable for various nutraceutical and wellness applications. High-quality and competitive price. Welcome to enquire with us at info@gybiotech.com.

COA

Item	Specification	Result	Method
Basic Product Information
Genus and Species	Morus alba L.	Conform	/
Part of the Plant	Leaf	Conform	/
Country of Origin	China	Conform	/
Marker Compounds
1-Deoxynojirimycin	≥5.0%	5.21%	HPLC
Organoleptic Data
Appearance	Powder	Conform	GJ-QCS-1008
Color	Deep Brown Fine Powder	Conform	GB/T 5492-2008
Odor	Characteristic	Conform	GB/T 5492-2008
Taste	Characteristic	Conform	GB/T 5492-2008
Physical Characteristics
Particle Size (80 mesh)	100% Pass 80 mesh	Conform	GB/T 5507-2008
Moisture	≤5.0%	2.08%	GB/T 14769-1993
Ash Content	≤5.0%	2.55%	AOAC 942.05, 18th
Density	0.3~0.5g/ml	Conform	ChP2020
Solvent Residue	Eur.Pharm	Conform	GJ-QCS-1007
Heavy Metals
Total Heavy Metals	<10ppm	Conform	USP <231>, method II
As	<2.0ppm	Conform	AOAC 986.15, 18th
Pb	<2.0ppm	Conform	AOAC 986.15, 18th
Cd	<0.5ppm	Conform	AOAC 986.15, 18th
Hg	<0.5ppm	0.08ppm	AOAC 971.21, 18th
Pesticide Residue
666	<0.2ppm	Conform	GB/T5009.19-1996
DDT	<0.2ppm	Conform	GB/T5009.19-1996
Microbiology
Total Plate Count	≤1,000cfu/g	Conform	AOAC 990.12, 18th
Total Yeast & Mold	≤100cfu/g	Conform	FDA (BAM) Chapter 18, 8th Ed.
E. Coli	Negative	Negative	AOAC 997.11, 18th
Salmonella	Negative	Negative	FDA (BAM) Chapter 5, 8th Ed.

What Are the Mulberry Leaf Extract Deoxynojirimycin Chemical Properties?

Structural Identity and Mimicry

Deoxynojirimycin (DNJ) is an iminosugar, a class of compounds where the oxygen atom in the sugar ring is replaced by a nitrogen atom. Its molecular structure, specifically a polyhydroxylated piperidine ring, is a near-perfect three-dimensional mimic of the natural sugar, D-glucose. This structural similarity is the cornerstone of its biological activity. Because mulberry leaf extract powder Deoxynojirimycin "looks" like glucose to cellular enzymes, it can bind to their active sites but cannot be processed further, effectively blocking their function. This property classifies DNJ as a potent competitive inhibitor, primarily targeting carbohydrate-digesting enzymes like alpha-glucosidase in the human gut.

Polarity and Stability

DNJ is a highly polar, water-soluble molecule due to the presence of multiple hydroxyl (-OH) groups and its basic amine (-NH) group within the ring. This polarity makes it extractable into aqueous solutions and influences its pharmacokinetics, limiting its passive diffusion across cell membranes. Regarding stability, mulberry leaf extract powder Deoxynojirimycin is relatively stable under standard storage conditions and moderate temperatures. However, as an organic compound, it can be susceptible to degradation under extreme pH or prolonged high heat, which is a consideration during the extraction and formulation processes from mulberry to ensure consistent potency in mulberry leaf extract powder.

Inhibition Nature

The nitrogen in its ring gives mulberry leaf extract powder Deoxynojirimycin its weakly basic, alkaloidal character. This influences its extraction, as it can form salts with acids, and its interaction with biological targets. The key chemical property stemming from this structure is its potent and specific inhibition of alpha-glycosidase enzymes. Chemically, DNJ's nitrogen atom creates a positively charged transition state analog that binds with much greater affinity to the enzyme's active site than the natural substrate (sucrose or maltose). This inhibition is reversible and competitive, meaning it directly competes with dietary sugars for the enzyme, thereby slowing their breakdown and absorption.

What Is Mulberry Leaf Extract Used For?

Mulberry leaf extract powder is from the leaves of the Morus alba tree, and is a concentrated form of the plant's bioactive compounds. Modern scientific research has now validated many of its traditional uses, identifying key components like 1-deoxynojirimycin (DNJ), flavonoids, and alkaloids as responsible for its effects.

1. Blood Sugar Management and Diabetes Support

This is the most well-researched and prominent use of mulberry leaf extract. It acts through several intelligent mechanisms to support healthy blood glucose levels. Firstly, it contains a compound called 1-deoxynojirimycin (DNJ), which acts as an alpha-glucosidase inhibitor. This means it slows down the breakdown of complex carbohydrates (like those in rice and bread) into simple sugars in the intestines. This slowing action prevents rapid spikes in blood sugar after a meal, creating a more gradual and manageable release of glucose into the bloodstream.

Secondly, research suggests that mulberry leaf extract powder Deoxynojirimycin may enhance the body's sensitivity to insulin, the hormone responsible for ushering glucose into cells for energy. Improved insulin sensitivity means the body can use its own insulin more effectively, helping to lower circulating blood sugar. For these reasons, it is widely used as a complementary dietary approach by individuals with type 2 diabetes or prediabetes, and by those seeking to maintain healthy metabolic function. It is crucial to note that it should not replace prescribed diabetes medication but may be used under medical supervision as part of a broader management plan.

2. Support for Healthy Cholesterol and Lipid Levels

Beyond blood sugar, mulberry leaf extract powder Deoxynojirimycin appears to have a favorable impact on lipid profiles, contributing to cardiovascular wellness. Studies indicate that it can help reduce levels of low-density lipoprotein (LDL), often called "bad" cholesterol, and triglycerides, which are fats circulating in the blood. Simultaneously, it may help support or increase levels of high-density lipoprotein (HDL), or "good" cholesterol.

The proposed mechanisms for this effect are multifaceted. The antioxidants in the extract may help prevent the oxidation of LDL cholesterol-a key step in the formation of arterial plaque. Furthermore, by improving overall metabolic efficiency and potentially reducing the liver's production of lipids, mulberry leaf extract powder helps create a healthier balance. This lipid-modulating effect, combined with its blood sugar benefits, makes it a holistic support for metabolic syndrome-a cluster of conditions that increase heart disease risk.

3. Antioxidant and Anti-Inflammatory Protection

Oxidative stress and chronic, low-grade inflammation are underlying factors in many modern chronic diseases and the aging process itself. Mulberry leaf extract is rich in potent antioxidant compounds like rutin, quercetin, and chlorogenic acid. These substances neutralize harmful free radicals-unstable molecules that can damage cells, proteins, and DNA.

By reducing oxidative stress, the extract also indirectly curtails inflammation. Several of its compounds have been shown to inhibit the production of pro-inflammatory signaling molecules in the body. This dual antioxidant and anti-inflammatory action provides systemic support, potentially protecting blood vessels, nerve cells, and other tissues from damage. It's a foundational benefit that supports all others, contributing to long-term cellular health.

4. Weight Management Aid

Mulberry leaf extract powder Deoxynojirimycin is frequently included in weight management formulations due to its synergistic effects on metabolism. Its role in carbohydrate metabolism is central here. Inhibiting the absorption of sugars from the diet may reduce the total caloric intake from carbohydrates. More importantly, it helps prevent the sharp insulin spikes that promote fat storage, particularly around the abdomen.

Some research also points to its potential to influence fat metabolism directly, encouraging the body to break down stored fat (a process called lipolysis) and inhibiting the formation of new fat cells. While mulberry leaf extract powder is not a magic weight-loss pill, when combined with a balanced diet and exercise, it can be a valuable tool by helping to regulate the appetite and metabolic drivers of weight gain, making it easier to adhere to a healthy lifestyle.

5. Promotion of Cardiovascular Health

Building on its blood sugar, cholesterol, and antioxidant benefits, mulberry leaf extract Deoxynojirimycin powder offers direct support for heart and blood vessel health. By contributing to healthier blood pressure levels (an effect noted in some animal and human studies), improving endothelial function (the health of the inner lining of blood vessels), and preventing plaque formation, it supports overall circulatory efficiency.

The combined effect of these actions is a reduced strain on the cardiovascular system. Healthy blood vessels are more flexible and better at regulating blood flow and pressure. This makes mulberry leaf extract a comprehensive botanical ally for long-term cardiovascular maintenance, focusing on the root causes of vascular dysfunction rather than a single symptom.

6. Liver Health Support

The liver is the body's primary metabolic and detoxification organ. Mulberry leaf extract powder Deoxynojirimycin demonstrates hepatoprotective (liver-protecting) properties in scientific models. The antioxidants in the extract help shield liver cells from damage caused by toxins, oxidative stress, and inflammation.

Furthermore, by improving lipid metabolism, it can help reduce the accumulation of fat in the liver-a condition known as non-alcoholic fatty liver disease (NAFLD), which is closely tied to insulin resistance and metabolic syndrome. By supporting the liver's metabolic functions and protecting its cells, mulberry leaf extract aids the body's natural detoxification processes and overall metabolic harmony.

Factory&Team：

Factory&Team