Bulk Spermidine Powder

Bulk Spermidine Powder Supplier:

Guanjie Biotech specializes in bulk spermidine powder research, production, testing, and trading. Our spermidine bulk powder uses plant extraction and bio-fermentation. It is a white powder with an assay of 1% and 98%. Spermidine contains an ideal dose of special wheat germ flour. Spermidine is ultra-pure and 100% plant-based. At Guanjie Biotech, the quality of our Bulk Spermidine Powder products is very important to us. All of our products are manufactured in carefully and rigorously tested facilities and meet the highest quality standards. When developing our products, we pay special attention to their compatibility and bioavailability. High quality and competitive price. Welcome to inquiry: info@gybiotech.com.

 

COA:

Test Items	Specification	Result	MOA
Appearance	White to off-white powder	Off-White Powder	Visual
Purity	≥98%	99.0%	GC
Solubility	Soluble in water	Conform	CP2020
Loss on drying	≤1.0%	0.28%	CP2020
Residue on ignition	0.2%	0.02%	CP2020
Ethanol(GC)	5000ppm	600ppm	GC
Heavy Metal Content
Pb	≤0.1 ppm	Conform	GB5009
Hg	≤0.1ppm	Conform	GB5009
Cd	≤0.2 ppm	Conform	GB5009
As	≤0.1ppm	Conform	GB5009
Total microbial count	≤500CFU/g	<10	GB4789
Coliform	≤0.92MPN/g	Conform	GB4789
Mold and yeast	≤50CFU/g	Conform	GB4789
Staphylococcus aureus	0/25g	Conform	GB4789
Salmonella	0/25g	Conform	GB4789
Conclusion	All inspection items are in conformity with the specifications.
Storage Condition	Sealed packaging, stored at cool, dry, and away from light.

 

What Is Spermidine?

Spermidine has the chemical structure formula C7H19N3. It comprises one amine group (NH) and two amino groups (NH2). Its molecular formula is shown below. It belongs to a colorless transparent crystal. Spermidine contains three nitrogen atoms in its chemical structure. Bulk spermidine powder has certain chemical and biological activities.

 

Where Can You Found Spermidine?

Bulk spermidine powder is found in many foods. It is especially high in legumes, whole grains, fermented foods, mushrooms, and some fruits. The body can synthesize spermidine itself. This takes place mainly in the liver, kidneys, and small intestine. However, the amount of spermidine produced by the body itself is affected by age, diet, gut microbiota genetic factors, etc. The amount of spermidine synthesized by the body itself begins to decline after the age of 30, and the decline becomes more pronounced after the age of 40.

 

Extraction Methods:

Guanjie Biotech uses two methods to extract bulk spermidine powder has two processes: plant extraction and bio-fermentation. Nowadays, the spermidine products on the market are mainly extracted from rice or wheat germ as raw material.

1. Plant-extracted spermidine

Plant-derived spermidine (Spermidine) production method is a method of extracting spermidine by physical and chemical means using natural plants as raw materials.

 

(1)Process:

•Raw material selection and pretreatment:

The first step of plant-derived spermidine is to select the appropriate plant raw material. We use wheat germ, which is rich in spermidine. The quality of the raw material directly affects the purity and yield of the final extract, so it needs to be strictly screened and tested. After selecting the raw material, it must be pre-treated by washing, drying, and crushing.

 

•Solvent extraction:

The pre-treated plant powder needs to be extracted using a suitable solvent. The purpose of this step is to dissolve bulk spermidine powder from the plant matrix. During the extraction process, temperature, pH, and time need to be controlled.

 

•Purification and concentration:

The extracted solution contains a variety of plant compounds. This requires a multi-step purification process to isolate and concentrate spermidine. Commonly used purification methods include membrane filtration, ion exchange chromatography, and liquid-liquid extraction. These methods can effectively remove impurities and improve the purity of bulk spermidine powder. Subsequently, the extract must be concentrated by evaporation, lyophilization, etc.

 

•Detection and quality control:

The extracted and purified bulk spermidine powder needs to undergo rigorous quality testing. Commonly used detection methods include high-performance liquid chromatography (HPLC) and mass spectrometry. These detection techniques can accurately determine the content of spermidine and detect the level of impurities in it.

 

•Packaging:

The packaging process requires strict control of environmental conditions to prevent degradation and contamination of spermidine. After packaging, the product undergoes a final quality inspection.

 

(2)Advantages of spermidine plant extract

•naturalness:

Plant-extracted spermidine is derived from natural plants and has high safety and biocompatibility. Compared with chemically synthesized spermidine, plant-extracted products are more in line with modern consumers' pursuit of natural and healthy products.

 

•Diversity:

Plants are rich in a variety of beneficial bioactive substances. In addition to bulk spermidine powder, it may also contain other ingredients that are beneficial to health. Such as antioxidants, vitamins, etc. Therefore, plant-derived spermidine products may have a wider range of health effects.

 

•Environmental friendliness:

The plant extraction process usually uses milder solvents and techniques. This reduces environmental pollution. The plant extraction process is more environmentally friendly than the chemical synthesis method.

 

2. Biological Fermentation of Spermidine

Biofermented bulk spermidine powder involves the cultivation of microorganisms, fermentation, and extraction.

(1)Production Process

•Strain Selection:

The production of fermented spermidine first requires the selection of a suitable microbial strain. Microorganisms that are capable of synthesizing spermidine in large quantities are usually selected. These strains are genetically modified or naturally selected to produce spermidine efficiently.

 

•Fermentation culture:

After selecting a suitable strain, it is placed in a fermenter for cultivation. During fermentation, the microorganisms convert nutrients in the medium into spermidine by metabolic action. Fermentation conditions such as temperature, pH, oxygen supply, and medium composition have a direct effect on the yield of spermidine, so precise control is required.

 

•Extraction and purification:

After fermentation is completed, bulk spermidine powder needs to be extracted from the fermentation broth. We usually use centrifugation to remove the bacteria and impurities. Then, further purification through liquid chromatography and other techniques, and finally high purity spermidine.

 

•Concentration and drying:

The purified spermidine solution usually needs to be concentrated and then converted into a powdered product by techniques such as spray drying or freeze drying, so that it can be easily preserved and transported.

 

 

(2)Advantages

•Natural source:

Biofermented spermidine is produced through the natural metabolism of microorganisms. It is closer to a natural source than chemically synthesized methods, reducing the risk of chemical contamination and residues.

 

•Efficient Production:

Advances in modern biotechnology allow the fermentation process to produce high concentrations of bulk spermidine powder in a relatively short period. By optimizing the strain and fermentation conditions, the production efficiency is greatly improved.

 

•High purity:

Through a rigorous purification process, the purity of bio-fermented spermidine is usually high. This can meet the requirements of food supplements and pharmaceutical applications.

 

•Environmentally friendly:

The fermentation process generally does not require the use of harmful chemicals. The production process produces less waste and it has less impact on the environment.

 

•High safety:

Due to the strict control of the bulk spermidine powder production process, bio-fermented spermidine is usually highly safe and suitable for long-term consumption.

 

Factory&Team：

 

Certification

 

Package & Shipment

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